It is estimated that almost 1,500,000\npeople may suffer from\nthe immune system disorder known as lupus. When afflicted with this\ndisorder, the immune system becomes over-active and begins to attack\ntissue throughout the body, confusing it with bacteria and other foreign\ninvaders. The result is inflammation, pain, and damage to otherwise\nhealthy organs and tissue. As more and more cases surface, finding safe\nand effective ways to treat this chronic illness is a top priority. One\npromising tool may be medical marijuana.
\nThe most common type of lupus is SLE, or systemic lupus erythematosus. A\n2005 study conducted by the Centers for Disease Control and Prevention\nfound a prevalence of 161,000 individuals with diagnosable SLE and\nanother 322,000 with probable SLE. Cutaneous lupus is another common\nform of this illness. Its symptoms include swollen glands and a scaly\nred rash on the cheeks and bridge of the nose.
\nIt is unclear why some people develop this condition, but there appears\nto be both a genetic and environmental component. Lupus tends to run in\nfamilies but is triggered by something in the environment, such as:
\nIt is more common in young women between the ages of 15 and\n40.\nPeople with lupus suffer flare ups of the disease throughout their life\nand can go into remission for long periods.
\nThe symptoms of lupus include:
\nThe treatment plan for lupus may include medical grade cannabis along\nwith nonsteroidal anti-inflammatory drugs and corticosteroids. A 2014\nstudy published in the Journal of Biological\nChemistry\nfound that medical marijuana has an immuno-modulatory effect. In other\nwords, it can help manage the inappropriate immune system responses seen\nin lupus and other immune system disorders.
\nThe study looked at the effect of THC, a component in cannabis, on\nregulating immune system responses. The immune system has a localized\ncannabinoid receptor type 2, or CBD2, that endocannabinoids in medical\nmarijuana influence. They increase the level of the anti-inflammatory\nprotein interleukin-10 while decreasing a protein responsible for\ninflammation called interleukin-2. The combination of these two\nresponses to cannabis may help ease the pain lupus suffers know all too\nwell.
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