{"componentChunkName":"component---common-build-question-tags-template-js","path":"/question-tag/acid-reflux/","result":{"data":{"allQuestion":{"edges":[{"node":{"id":"Question_12316-markdown","title":"Can CBD help with GI issues? ","slug":"can-cbd-help-with-gi-issues","content":"\"Specifically IBS, IBD, and GERD?\"\n_____________________\nHi there!\n\nThe endocannabinoid system (ECS) is largely devoted to maintaining homeostasis (the tendency of organisms to auto-regulate and maintain their internal environment at equilibrium). Deficiency or malfunction of the ECS has become a focus for researchers seeking treatment options for several maladies—especially those that have few, if any, effective pharmocotherapeutic interventions, such as celiac disease, MS, fibromyalgia, IBD and IBS. In fact, the scientific community has recently termed the ECS malfunction: Clinical Endocannabanoid Decifiency, or CEDC. CBD works by balancing and supporting the ECS through its subtle effects on cannaboinoid receptor-1 (CB1) and cannaboinoid receptor-2 (CB2) receptors, as well as other receptors that modulate serotonin, GABA, dopamine, and many more.\nIn IBD and GERD, inflammation is central to both the etiology and symptomology of the respective disease. CBD is well known as an effective immunomodulator and anti-inflammatory, and those properties still do apply to GI inflammation. However, unique to the GI tract, are specialized nerve cells called enteric glial cells— \"the glue of the nteric nervous system (ENS)\"—which, when overactive, also contribute to acute and chronic GI inflammation. Recent pre-clinical research suggests that CBD may lower GI inflammation by controlling reactive gliosis in the ENS. Or, in other words, CBD restores homeostasis in the gut by reducing hyperactivity in enteric glial cells.\n\ndrkim\n_____________________\nThe ENS is an extensive network of neurons supported by enteric glial cells (the above mentioned \"glue\" on the ENS). Two neural plexuses comprise the ENS: the myenteric plexus, involved in motility/peristalsis; and the submucosal plexus, involved in intestinal and gastric secretions. CBD works to restores homeostasis in the ENS via modulation of enteric glial cells (as mentioned above), the myenteric plexus, and the submucosal plexus.\n\nAlthough inflammation plays little, if any, role in the pathology of IBS, CBD's balancing of the myenteric plexus lessens inappropriate and painful intestinal contractions; while balancing of the submucosal plexus reduces inappropriate gastric and intestinal secretions. CBD's effects on glial cells, the submucosal plexus and myenteric plexus factor into CBD's ability to alleviate symptoms of GERD, IBS and IBD.\n\nAn ongoing, randomized, placebo controlled, double-blind, cross-over trial has shown chewable CBD to significantly reduce IBS-related pain. To be included in the study, it was also necessary that patients experienced, according to their own account, at least three pain episodes per week of a predefined intensity. All patients who participated in the study experienced decrease in their levels of pain score. On top of the overall reduction, the trend curve suggests 50% higher pain reduction.\n\ndrkim\n_____________________\nFurthermore, several studies show that among patients who seek medical attention for IBS or IBD, around 70% of IBS patients, and 30% of IBD patients, have psychiatric comorbidity—depression and generalized anxiety disorder being most common. CBD increases serotonin signaling at the 5-HT1A receptor—the same neurotransmitter and receptor that SSRIs like Prozac influence—which is mostly why CBD has antidepressant and anxiolytic properties. In fact, SSRIs and tricyclic antidepressants (which also increase serotonin signalling), have been shown to alleviate anxiety and depression symptoms, as well as alleviate some of the abdominal pain and bowel symptoms involved in IBS, IBD and gastroesophageal reflux disease (GERD), which is why SSRIs and TCAs are commonly prescribed for IBS and IBD.\n\nI hope this helps!\n\ndrkim","image":null}},{"node":{"id":"Question_12315-markdown","title":"Can CBD help with GI issues?","slug":"can-cbd-help-with-gi-issues-1","content":"\"Like IBS, IBD and GERD?\"\n_____________________\nHi there!\nThe endocannabinoid system (ECS) is largely devoted to maintaining homeostasis (the tendency of organisms to auto-regulate and maintain their internal environment at equilibrium). Deficiency or malfunction of the ECS has become a focus for researchers seeking treatment options for several maladies—especially those that have few, if any, effective pharmocotherapeutic interventions, such as celiac disease, MS, fibromyalgia, IBD and IBS. In fact, the scientific community has recently termed the ECS malfunction: Clinical Endocannabanoid Decifiency, or CEDC. CBD works by balancing and supporting the ECS through its subtle effects on cannaboinoid receptor-1 (CB1) and cannaboinoid receptor-2 (CB2) receptors, as well as other receptors that modulate serotonin, GABA, dopamine, and many more.\n\nIn IBD and GERD, inflammation is central to both the etiology and symptomology of the respective disease. CBD is well known as an effective immunomodulator and anti-inflammatory, and those properties still do apply to GI inflammation. However, unique to the GI tract, are specialized nerve cells called enteric glial cells— \"the glue of the enteric nervous system (ENS)\"—which, when overactive, also contribute to acute and chronic GI inflammation. Recent pre-clinical research suggests that CBD may lower GI inflammation by controlling reactive gliosis in the ENS. Or, in other words, CBD restores homeostasis in the gut by reducing hyperactivity in enteric glial cells.\n\ndrkim\n_____________________\nThe enteric ENS is an extensive network of neurons supported by enteric glial cells (the above mentioned \"glue\" on the ENS). Two neural plexuses comprise the ENS: the myenteric plexus, involved in motility/peristalsis; and the submucosal plexus, involved in intestinal and gastric secretions. CBD works to restores homeostasis in the ENS via modulation of enteric glial cells (as mentioned above), the myenteric plexus, and the submucosal plexus.\n\nAlthough inflammation plays little, if any, role in the pathology of IBS, CBD's balancing of the myenteric plexus lessens inappropriate and painful intestinal contractions; while balancing of the submucosal plexus reduces inappropriate gastric and intestinal secretions. CBD's effects on glial cells, the submucosal plexus and myenteric plexus factor into CBD's ability to alleviate symptoms of GERD, IBS and IBD.\n\nAn ongoing, randomized, placebo controlled, double-blind, cross-over trial has shown chewable CBD to significantly reduce IBS-related pain. To be included in the study, it was also necessary that patients experienced, according to their own account, at least three pain episodes per week of a predefined intensity. All patients who participated in the study experienced decrease in their levels of pain score. On top of the overall reduction, the trend curve suggests 50% higher pain reduction.\n\ndrkim\n_____________________\nFurthermore, several studies show that among patients who seek medical attention for IBS or IBD, around 70% of IBS patients, and 30% of IBD patients, have psychiatric comorbidity—depression and generalized anxiety disorder being most common. CBD increases serotonin signaling at the 5-HT1A receptor—the same neurotransmitter and receptor that SSRIs like Prozac influence—which is mostly why CBD has antidepressant and anxiolytic properties. In fact, SSRIs and tricyclic antidepressants (which also increase serotonin signalling), have been shown to alleviate anxiety and depression symptoms, as well as alleviate some of the abdominal pain and bowel symptoms involved in IBS, IBD and gastroesophageal reflux disease (GERD), which is why SSRIs and TCAs are commonly prescribed for IBS and IBD.\n\nI hope this helps!\n\ndrkim","image":null}},{"node":{"id":"Question_9072-markdown","title":"Is there any CBD or cannabis strains that can help with GERD?","slug":"is-there-any-cbd-or-cannabis-strains-that-can-help-with-gerd","content":"\n_____________________\nHi there! Please check out these previously answered questions on the matter, hope it helps!: \nhttps://www.hellomd.com/answers/5a13763af32a1300069cd4c9/can-cannabis-help-with-gerd-or-ulcers\n\nashleigh","image":null}},{"node":{"id":"Question_8591-markdown","title":"Can cannabis help with GERD or ulcers?","slug":"can-cannabis-help-with-gerd-or-ulcers","content":"\n_____________________\nHello,\nThere is a plenty of anecdotal evidence to support cannabis as a viable adjunctive treatment for both issues. There are also a few animal studies which might explain cannabis' efficacy in treating both GERD and ulcers. \n\nAnatomical, physiological and pharmacological studies have shown that the endocannabinoid system is widely distributed throughout the gut, with regional variation and organ-specific actions. It is involved in the regulation of food intake, nausea and emesis, gastric secretion and gastroprotection, GI motility, ion transport, visceral sensation, intestinal inflammation and cell proliferation in the gut. Cellular targets have been defined that include the enteric nervous system, epithelial and immune cells. Activating cannabinoid receptors has been demonstrated to inhibit gastrointestinal fluid secretion and inflammation in animal models. Studies indicate that cannabinoids in marijuana bind with cannabinoid receptors in the digestive tract, especially the small and large intestine.\n\n\ndrkim\n_____________________\nHello,\nThere is plenty of anecdotal evidence to support cannabis as a viable adjunctive treatment for both issues. There are also a few animal studies which might explain cannabis' efficacy in treating both GERD and ulcers.\nAnatomical, physiological and pharmacological studies have shown that the endocannabinoid system is widely distributed throughout the gut, with regional variation and organ-specific actions. It is involved in the regulation of food intake, nausea and emesis, gastric secretion and gastroprotection, GI motility, ion transport, visceral sensation, intestinal inflammation and cell proliferation in the gut. Cellular targets have been defined that include the enteric nervous system, epithelial and immune cells. Activating cannabinoid receptors has been demonstrated to inhibit gastrointestinal fluid secretion and inflammation in animal models. Studies indicate that cannabinoids in marijuana bind with cannabinoid receptors in the digestive tract, especially the small and large intestine.\n\n\ndrkim","image":null}},{"node":{"id":"Question_8586-markdown","title":"Does cannabis help with ulcers or GERD? Also, could you give an example treatment regimen?","slug":"does-cannabis-help-with-ulcers-or-gerd-also-could-you-give-an-example-treatment-regimen","content":"\"@\"","image":null}},{"node":{"id":"Question_8370-markdown","title":"What type and form of cannabis is best to manage acid reflux? ","slug":"what-type-and-form-of-cannabis-is-best-to-manage-acid-reflux","content":"\n_____________________\nTHC rich strains have been shown to act on the lower esophageal sphincter to decrease reflux of stomach acids back up into the esophagus.\n\nGERD symptoms are caused by a malfunction of the lower esophageal sphincter which causes stomach acids to reflux back up causing the heartburn symptoms.\n\nI would look for a THC dominant strain. It may be best to use vape, sublingual tincture form for rapid onset of action.\n\n I am quoting from the \"Asian Pacific Journal of Tropical Medicine\":\n\"There is evidence that CB1 receptor stimulation with synthetic cannabinoids or Cannabis sativa extracts rich in Δ9-tetrahydrocannabinol inhibit gastric acid secretion in humans and experimental animals.\"\n\nhttp://www.sciencedirect.com/science/article/pii/S1995764516300712\n\nrachelnp","image":null}},{"node":{"id":"Question_10082-markdown","title":"Does anyone have any suggestions for constant throat clearing due to acid reflux. Will CBD lozenges work? ","slug":"does-anyone-have-any-suggestions-for-constant-throat-clearing-due-to-acid-reflux-will-cbd-lozenges-work","content":"\n_____________________\nCannabis seems to be very helpful for acid reflux and I think it would help with constant throat clearing. I would try the lozenges, and also a tincture. Some people report that inhaled cannabis seems to help with acid reflux as well.\n\nandrewvanmd","image":null}},{"node":{"id":"Question_7402-markdown","title":"Does cannabis help with GERD?","slug":"does-cannabis-help-with-gerd","content":"\"Is there any information regarding cannibas helping GERD\"\n_____________________\nYes cannabis helps with GERD (gastro-esophogeal reflux disease). I have spoken with many patients who find relief with inhaled cannabis as well as with tinctures and other forms. Cannabis seems to help regulate some of the muscles and sphincters that are often disfunctional in GERD.\n\nandrewvanmd","image":null}},{"node":{"id":"Question_7170-markdown","title":"Fibromyalgia, chronic pain and GERD.","slug":"fibromyalgia-chronic-pain-and-gerd","content":"\"First time on the webpage and its time for me to get some product. I have fibro and I have chronic pain from a couple of injuries I sustained. Oh and since I have GERD, I don't want to be inhaling since I don't want to cough! Any suggestions on what I need to purchase?\"\n_____________________\nFor our Patients, we recommend our CBD Gummies, it's a good alternative to vaping or smoking flower. We've had countless fibro, PTSD, chronic pain sufferers swear by our CBD, some have even completely stopped taking pills. Good thing about CBD, you don't have to be a California Resident, Medical Card holder, or even live in this country. I can ship this to you wherever you are since there is no THC in that product. Let us know, we can help!\n\nmetafizics","image":null}},{"node":{"id":"Question_10825-markdown","title":"IBS mixed type symptoms, GERD and cannabis management?","slug":"ibs-mixed-type-symptoms-gerd-and-cannabis-management","content":"\"I have GERD, as well as lifelong IBS mixed type symptoms, in addition to anxiety and depression. I had an emergency cholecystectomy due to rupture/infection 7 years ago, and my IBS type symptoms have increased, rather than decreased. My gastroenterologist thinks I may have a vagus nerve issue, and suggested trying CBD/whole plant extracts as \"a last resort\" for pain caused by all of these mixed bag issues, as he's stumped as well.\n\nI've started keeping a pain/symptom journal and have about six months of symptoms recorded daily; I've also since gotten my card, and started recording microdosages and results from that. Is there any way of better recording and managing my symptoms with CBD/CBN? Should I try any particular types of tinctures?\"\n_____________________\nCannabis may be helpful in the treatment of irritable bowel syndrome, because it has immunomodulatory and anti-inflammatory properties. It is also effective in alleviating symptoms such as nausea, vomiting, and crampy abdominal pain. Because cannabis may reduce GI motility, it may also be helpful for diarrhea.\n\nCannabis is also thought to be helpful for GERD, because there is evidence that cannabis decreases transient lower esophageal sphincter relaxation. It is also helpful for pain and may lessen discomfort associated with acid reflux.\n\ndredmunds","image":null}},{"node":{"id":"Question_10766-markdown","title":"Is acid reflux easily treated with cannabis?","slug":"is-acid-reflux-easily-treated-with-cannabis","content":"\"I've had this issue for a long time and tried all sorts of medications, but nothing proves all that effective. I also watch what I eat and drink. I've been to the doctor several times and he's ruled out any more serious stuff.\"\n_____________________\nThere are some studies that indicate that some forms of medical cannabis can interact with the endogenous cannabinoid system to reduce and help problems such as the gastroesophageal reflux disease. \n\nMost acid reflux problems comes from a low production of hydrochloric acid, or achlorhydria, thus by altering your stomach pH. After a chain of events you can feel the burning and discomfort upon reaching your esophagus.\n\nAs an alternative and healthy method, you should avoid high-sugar foods, such as chocolats and candies, and try a low carb diet, which has been very effective clinically and also in some specific studies. \n\nThere are plenty other alternatives you can consider; One that i enjoy and its a common method of supplementing for low stomach acid, is the Betaine Hydrochloride, or Betaine HCL supplement. \nIt will improve your digestion, and it will help with your reflux. \n\nAlso consider taking a blood test for vitamin b12, since acid reflux problems tends to disturb B12 absorption, and drugs like Nexium, supress your stomach acid secretion, causing then a B12 deficiency. \n\nYou should consider visiting an specialist.\n\nHope this helps!\n\nGabriel Henriques","image":null}}]}},"pageContext":{"limit":12,"skip":0,"numPages":1,"currentPage":1,"id":4914,"name":"Acid Reflux","slug":"acid-reflux","country":"US"}},"staticQueryHashes":["3949754563","4179947113","4202924991"]}