{"componentChunkName":"component---common-build-question-tags-template-js","path":"/question-tag/alzheimer's-disease/","result":{"data":{"allQuestion":{"edges":[{"node":{"id":"Question_9234-markdown","title":"What will help with dementia?","slug":"what-will-help-with-dementia","content":"\n_____________________\nHi there! Check out these resources - https://www.hellomd.com/health-wellness/565e887ba4f004000b0000df/medical-cannabis-counseling-helping-dementia-and-cancer-patients-find-relief\nhttps://www.hellomd.com/answers/5a7a3a2e1cd81600086f344a/what-strength-of-cbd-and-thc-is-best-for-parkinsons-and-moderate-dementia\n\nIn addition, please feel free to utilize the search feature on our website. We have a lot of content re: dementia, and I hope you'll find something valuable.\n\nhttps://www.hellomd.com/search?term=dementia\n\nI hope this helps!\n\nmelissa","image":null}},{"node":{"id":"Question_9176-markdown","title":"What strength of cbd and thc is best for Parkinson’s and moderate dementia?","slug":"what-strength-of-cbd-and-thc-is-best-for-parkinson-s-and-moderate-dementia","content":"\"Dad has Parkinson’s and recently was diagnosed with moderate dementia and is aggressive combative. I was told cbd oils for day time to keep him calm and thc at night to help him sleep . But what would be the best dosage? I already bought the 200 mg cbd oil and tried   It once and it didn’t work . So I’m guessing he needs a stronger miligrams . Is there a milligrams that can be recommended. Also someone mentioned indica strength is best . I am new to this. Any information is awesome \"\n_____________________\nHello, I can try to help from my experience. My mother has advanced dementia and was very agitated, walking around and falling. She is very calm now with around 180-200 mg of CBD daily divided in smaller doses. i also give her medical cannabis CBD: THC 1:1 in small doses, because THC makes her agitated and combative. I don't know the dose because I have made cannabutter my self so I go by feeling. She is never stoned but very calm. I hope I helped you in some way, if you have any more questions i will be glad to help :)\n\nkanica","image":null}},{"node":{"id":"Question_9175-markdown","title":"Parkinson’s & Dementia ","slug":"parkinsons-and-dementia","content":"","image":null}},{"node":{"id":"Question_9086-markdown","title":"CBD for motor problems in dementia?","slug":"cbd-for-motor-problems-in-dementia","content":"\"I have read this:  (copy paste)\n\n'To treat movement problems (Huntington’s disease, Parkinson’s, dementia): 3 to 5 mg of CBD oil per pounds of body weight daily. If you weigh 150 lbs, that would be 450 to 750 mg daily. '\n\nDo you know anything about this? My mother has dementia and is loosing the ability to walk. I give her about 200 mg of cbd and  it works fantastic for her agitation and anxiety but she walks even less now. Should increase the dose? any sugestion?\"\n_____________________\nYou do not say where that quote comes from and I want to be clear that there is no medical literature defining CBD doses for ANYTHING.  CBD is remarkably benign in the human body and there are essentially no reports of toxicity, but at the same time there is no body of clinical studies defining a dosage range for any condition.  Most reports of using CBD for various conditions are basically anecdotal, and the kind of dose-response information you are seeking is still folk medicine, not based on medical science.  It is also not clear to me what other factors might be affecting you mother's ambulation, so the best I can suggest is that increasing the CBD dose is unlikely to cause any adverse effects and if the lack of walking is from CBD related sedation her response will likely be to walk less.  If it helps, then I would not be concerned about a modest increase in dose unless other symptoms appear. \n\ndrelkind","image":null}},{"node":{"id":"Question_8161-markdown","title":"Is there any credible evidence that cannabis can stop or slow Alzheimer's?","slug":"is-there-any-credible-evidence-that-cannabis-can-stop-or-slow-alzheimers","content":"\"Is there any credible evidence that Cannabis can help or even stop the \"progress\" of early stage Alzheimer's in sufferers who are still healthy otherwise and under the age of 70.\"\n_____________________\nOne recent study found THC, the psychoactive ingredient in cannabis, stimulates the removal of toxic plaque in the brain, a common feature of the disease. It was also discovered that THC blocks inflammation, which damages neurons in the brain. Dutch scientists found two studies showing THC is useful in treating the behavioral symptoms of dementia. Similarly, a very small 2016 study of 11 participants found THC helped decrease symptoms of delusions, agitation or aggression, irritability, apathy and sleep in patients with Alzheimer's disease. Unfortunately, there are still no effective therapies for stopping Alzheimer's and other neurodegenerative conditions. There are three main goals of treatment and they aim to improve the quality of life of the person with the disease.\n\n1. Slowing the progression of the decline and treating symptoms with medications prescribed by their doctor.\n2. Managing the behavioural symptoms of Alzheimer's disease by consulting with the staff from your local Alzheimer Society, social workers, nurses or support groups.\n3. Providing support for both the person with the disease and their family caregiver.\n\nnptherasse","image":null}},{"node":{"id":"Question_8099-markdown","title":"What is the dosage of CBD for dementia?","slug":"what-is-the-dosage-of-cbd-for-dementia","content":"\"My dad has dementia. We have CBD oil derived from hemp. How much and how often should he take it?\"\n_____________________\nHere is an article on the subject https://www.tokeofthetown.com/2013/02/cbd_reverses_dementia_in_australian_study.php/\nthere is no standard dosing for cannabis. Make sure that you have a product that has therapeutic levels of CBD. Does your label on your hemp product say how much CBD is in the bottle? CBD from cannabis strains usually have much higher levels of CBD than derived from hemp.\n\nPiantaTinta","image":null}},{"node":{"id":"Question_7585-markdown","title":"What would you recommend for a bi-polar, paranoid, Alzheimer's patient? ","slug":"what-would-you-recommend-for-a-bi-polar-paranoid-alzheimers-patient","content":"\"Should they try CBD or marijuana products with both CBD and THC?\"\n_____________________\nAlz usually responds to low doses on the order of 15 mg per day. Clients are usually older so can be more sensitive to doses than younger people. In one very successful case topical application of a 10mg/ml cream was used. Dementia case Teresa, with slides 105s  https://youtu.be/AIXAiGx4OOk . She has Down's Syndrome but she was a very sweet lady until onset of Alz which is quite common in this condition. Her sister last week told me that Teresa became so aggressive that the sister feared for her own life. That reversed with just a few weeks of topical CBD.\n\ndrblair","image":null}},{"node":{"id":"Question_9812-markdown","title":"Does marijuana help with paranoid dementia?","slug":"does-marijuana-help-with-paranoid-dementia","content":"\"Does CBD or THC help? Or is it a combination of both cannabinoids?\"\n_____________________\nIn preliminary studies, cannabis is showing some promise for the treatment of dementia.  In one study, a small dose of THC was used to help nighttime behavioral changes, and the anti-oxidant effects of CBD have been purported to help the underlying changes that lead to dementia.  However, more studies in humans are needed.\n\ndrbultman","image":null}},{"node":{"id":"Question_9645-markdown","title":"Can cannabis help memory loss from dementia?  Or at least slow the progress of dementia?","slug":"can-cannabis-help-memory-loss-from-dementia-or-at-least-slow-the-progress-of-dementia","content":"\n_____________________\nHi there! Please check out these articles that discuss cannabis-use and memory loss - \n\n\nMedical Cannabis Counseling: Helping Dementia and Cancer Patients Find Relief\nhttps://www.hellomd.com/health-wellness/medical-cannabis-counseling-helping-dementia-and-cancer-patients-find-relief\n\nAlzheimer's and Medical Marijuana: Mind-Saving, Not Mind-Blowing\nhttps://www.hellomd.com/health-wellness/55959a553063310006070000/alzheimers-and-medical-marijuana-mind-saving-not-mind-blowing\n\nVeronicaB","image":null}},{"node":{"id":"Question_10925-markdown","title":"What is best for Lewy body dementia?","slug":"what-is-best-for-lewy-body-dementia","content":"\"I have LBD. What products would be best for this?\"\n_____________________\nThe wiki-pedia entry for Lewy body dementia sounds frightening. I have not had the opportunity to treat a patient with this disease, or notice its features in person. It sounds like rapidly progressive dementia along with hallucinations and poor executive functioning. I would try CBD rich cannabis, that also contains THC; inhaled as well as sublingual tincture. It seems that our brains' \"rust\" and we need to prevent oxidation. CBD and other cannabinoids play a roll in protecting our neurons. The scientific evidence looks for very promising, but the stigma and criminal penalties remain.\n\nandrewvanmd","image":null}},{"node":{"id":"Question_10924-markdown","title":"What is best for Alzheimer’s disease?","slug":"what-is-best-for-alzheimer-s-disease","content":"\n_____________________\nAlzheimer's disease consists of plaques and tangles in the brain that damage & kill the nerve cells and their ability to communicate with one another and other areas of the body. Since we do not know what is causing Alzheimer's disease, effective treatment is difficult to design. Alzheimer's disease as we know it has really only been discovered for the past 15 years. Israel has been doing research regarding Alzheimer's and treated Alzheimer's effectively with CBD cannabis as both a prevention and a treatment. CBD cannabis does appear to be neuroprotective according to the research at this time but further information will be released in the future. Since pesticides and herbicides are known to cause brain dysfunction it would be prudent to remove all unnecessary chemicals from one's environment. Antidepressants are known to increase prolactin levels in humans and can effectively stop the excretion of hormones like HGH and the patient will prematurely age due to the antidepressant so I advise most patients to get off the SSRI meds and to treat depression more appropriately. Exercise is essential to pump fluid throughout the body including the brain. If a person sits all the time there bring can become like a stagnant pond. I encourage the use of a super high CBD, low THC sublingual tincture twice daily but we have no long-term studies at this time.\n\ndrolson","image":null}},{"node":{"id":"Question_10656-markdown","title":"What can you recommend for someone that suffers from Alzheimer's?","slug":"what-can-you-recommend-for-someone-that-suffers-from-alzheimers","content":"\"Should they use marijuana products that contain both THC and CBD? Or, is one more effective than the other? Are there better routes of administration (i.e. vaping, edibles, tinctures)?\"\n_____________________\nCannabis is an extremely safe herb with no potential for overdose or toxicity. There is no danger in using cannabis oil in high doses for extended periods of time. I would try a whole plant tincture extract of cannabis that contains CBD and THC as well as the other naturally occuring components. A good starting dose would be 10 milligrams of cannabinoids two or three times per day. Observe closely for effects and adjust the dose as needed.\n\nandrewvanmd\n_____________________\nRemove excess saliva from the mouth. Allow the tincture to absorb in the mouth, to ensure direct absorption into the bloodstream. A good starting dose would be 10 milligrams of cannabinoids two or three times per day. Observe closely for effects and adjust the dose as needed.\n\nandrewvanmd\n_____________________\nI think Dr. Vanderveer's recommendation for administering CBD oil to be spot on.  If you wanted to try another option, you can try putting the same dosage/dropper amount in hot tea or drinks.  Many of my patients report that the time to onset is just as rapid as if it were dosed sublingually.  I hope this helps!\n\ndrpark\n_____________________\nSince we are likely talking about a person who's health has already been compromised, you must use caution administering any cannabis. The Alzheimer's patient must have a recommendation and you must be the caretaker in order to administer the medicine. Please start with a low dose of around three drops, sublingually, four times per day and every 2 to 3 days you may add three more drops until you are up to 20 drops per day. At the second week as long as the blood pressure is steady you can try going to 10 drops twice daily and stay at that dose for 2 to 3 weeks. Ultimately the dosage may need to be increased just 30 drops per day and three divided doses. Since every person responds differently, please monitor and log this patient's response to the medication an adjusted dosage appropriately and give us feedback on how this patient is doing. I do wonder about the other potential medical issues that caused the Alzheimers since this disease does not just fall out of the sky. Alzheimer's has an underlying cause and appropriately targeting that cause will produce the best outcome, is it low Vitamin D3, diabetes, toxic chemicals, too many western drugs like statins or bladder medicines that are known to cause Alzheimers as the culprit?\n\ndrolson\n_____________________\nThe lowest effective doses of THC (that cause observable biologic change) are approximately 2.5mg, however, most patients do not report subjective of \"self-perceivable\" change until about 5mg. Elderly patients new to cannabis, may be more sensitive to the effects of THC due to body composition changes that occur with age as well as lack of exposure. THC has been show to be \"neuroprotective\" and is known to be anti-inflammatory as well as promotional of neurologic recovery in acute neurologic insults. \n\nWhile THC shows benefit, the \"whole plant\" may be beneficial in producing relief for multiple symptoms that accompany Alzheimer's Disease due to the \"entourage\" effect of the other cannabinoids and terpenes in the plant. There are many ways to obtain cannabis, but sublingual elixirs and tinctures or edibles may be the easiest delivery for elders. \n\nEdibles are excellent and last longer, but use with caution in seniors as THC converts to a more potent derivative (11-hydroxy THC) after ingestion. I always recommend adults over the age of 70 start with lower than recommended doses of THC when using edibles until impact is determined. \n\nRemember that it may take between 1-2 hours to see the effects of edible cannabis and the effects can last up to 8 hours. Sublingual (under the tongue) delivery takes effect in 10-20 minutes and may last an average of 4-6 hours. Edibles may work best for nighttime in some patients due to prolonged drowsiness. \n\nAlzheimer's patients, depending on stage of disease, may have severely impaired ability to discern reality versus cognitive experience, and I recommend you observe you Mother closely as you work out dosing as some hallucinatory effects of THC and 11 hydroxy-TCH could be disturbing. You may want to keep a journal of symptoms and behaviors over time to determine dosing and effectiveness.\n\nAs a Geriatrician by training, I am excited about the possibilities that cannabis may hold for treatment of age-related neuro-degenerative diseases and; look forward to more detailed studies and recommendations in this area. \n\ndrgerhart\n_____________________\nThere have been several preclinical studies showing that small amounts of THC can slow the production and inhibit the aggregation of beta-amyloid proteins, the hallmark of Alzheimer's and  key  contributors to the progression of the disease.  There is abundant anecdotal evidence that, in many patients, cannabis helps mitigate  symptoms  associated with Alzheimer's - agitation, depression, anxiety, poor appetite, and insomnia. One recently published Israeli study, while small (10 patients), reported a significant  decrease in the severity of delusions, agitation/aggression, irritability, apathy, sleep and caregiver distress. And they concluded that adding cannabis oil was safe and a promising treatment option. \n\ndrfrye\n_____________________\nWe are not qualified medical professionals to adequately assess the condition, but I did find an interesting article that might help shed some light on the subject: http://www.alzheimers.net/6-15-15-effects-of-medical-marijuana-on-alzheimers/\n\nmari\n_____________________\nHere is some more information on using marijuana and its effect on Alzheimers Disease:\n\nhttps://www.hellomd.com/search/Alzheimer/articles\n\nhttps://www.hellomd.com/search/Alzheimer\n\nmark\n_____________________\nJust to reiterate, I am not a medical professional and you should always speak with your doctor before adding cannabis or any medicinal herb into your health care regime.  I have heard of patients having success with combining other herbs with cannabis to support healthy brain function. \n\nkivaanastasia\n_____________________\nThere was a study performed that showed promising results for Alzheimers resulting in a decrease in Alzheimer plaques. I would recommend a CBD:THC ratio of 20:1 twice daily every day. Any ratio of CBD:THC >10:1 will not make you \"high.\" It will take about 2-3 weeks for full efficacy. Titrate your dose up as you see fit as you will build tolerance (1 drop twice daily, may increase to 2 drops twice daily for instance and more).  This ratio also helps with decreasing aggression as seen with autistic children and is also used for anxiety, depression and muscle tension.  For aggression, you may use it every 3-6 hours as needed on top of twice daily.\n\ndrb\n_____________________\nA preclinical study published in the Journal of Alzheimer’s Disease found that very small doses of tetrahydrocannabinol (THC), a chemical found in marijuana, can slow the production of beta-amyloid proteins, thought to be a hallmark characteristic and key contributor to the progression of Alzheimer’s.\n\nThe study, published in 2014, is among others to support the effectiveness of THC in prohibiting the growth of toxic amyloid plagues.\n\nAnother study from the Salk Institute in La Jolla, California has also found that tetrahydrocannabinol and other compounds found in marijuana may reduce the amount of beta amyloid in the brain. Beta amyloid is a hallmark characteristic of Alzheimer’s and is commonly thought to cause the neurodegenerative disease.\n\nWhile the findings are preliminary, researchers are optimistic about their findings. David Schubert, professor at the Salk Institute and senior author on the study says, “Although other studies have offered evidence that cannabinoids might be neuroprotective against the symptoms of Alzheimer’s, we believe our study is the first to demonstrate that cannabinoids affect both inflammation and amyloid beta accumulation in nerve cells.”\n\nIn the study, researchers found that by exposing beta amyloid proteins to THC, it reduced the levels of beta amyloid, stopped the inflammatory response from the nerve cells caused by beta amyloid and allowed the nerve sells to survive. Antonio Currais, a postdoctoral researcher and first author on the paper noted:\n\n“Inflammation within the brain is a major component of the damage associated with Alzheimer’s disease, but it has always been assumed that this response was coming from immune-like cells in the brain, not the nerve cells themselves. When we were able to identify the molecular basis of the inflammatory response to amyloid beta, it became clear that THC-like compounds that the nerve cells make themselves may be involved in protecting the cells from dying.”\n\nThe take home from this article is that not only is there evidence that THC can slow the progression of AD, there is also some very exciting preliminary evidence that THC can also treat AD by reducing the levels of beta-amyloid plaques and the resulting inflammatory response which causes the death of brain cells and the resulting symptoms associated with AD.\n\nTherefore, I strongly recommend a product with a healthy amount of THC such as the conventional indicas, hybrids and sativas or also the extract products such as the oils and tinctures. However, as noted, those products should have THC at a higher ratio than is standard for many of the more common maladies CBD oils are being used for.\n\ndrkim\n_____________________\nAlzheimer's can certainly be a devastating illness for both the patient and family, and since \"traditional\" medicines are often ineffective, it makes sense to try cannabis therapy.  THC and CBD, the 2 most prominent active ingredients in cannabis, have quite different effects and are often used in combination for a more balanced effect.  The product you choose will somewhat depend upon what symptoms you are looking to treat, and daytime vs. nighttime use for instance.  CBD by itself does not have known intoxicating/psychoactive effects, and can have a calming effect in those suffering from anxiety/agitation.  THC could be useful to help stimulate appetite and induce sleep, but also has psychoactive effects that can be difficult to predict for a patient who could already be suffering from distressing mental dysfunction.  You would want to start with a small dose of THC, 2.5 mg or less, and increase only as tolerated.  If you choose to use a THC-containing product, it would be wise to make sure it is combined with CBD to help mitigate side effects.  In preliminary studies, cannabis shows promise in slowing Alzheimer's plaque deposits, so in addition to relieving the symptoms of Alzheimer's, cannabis may also be able to slow underlying disease progression.  We wish you the best of luck in pursuing this therapy, and as other physicians have mentioned, it's wise to make sure you have extra help on hand and keep close notes of the medication effects.\n\ndrbultman\n_____________________\nAs my physician colleagues have noted on this thread, cannabis preparations containing THC should be started at low doses when being taken by patients with Alzheimer's disease, cautiously increasing the amount as tolerated.   In addition, there is excellent published evidence showing CBD modifies THC effects, in particular reducing stimulation that can result in anxiety, so I would be careful to include significant amounts of CBD in whatever preparation is being used.  Without knowing the degree of the patient's cognitive impairment it's hard to give more specific advice, and I would advocate significant caution in introducing psychoactive agents if a patient is already displaying severe cognitive impairment.  As has been suggested, CBD may provide some calming effects without being psychoactive, and tinctures or lozenges with a 20:1 CBD:THC ratio might be a reasonable place to start, if medicinal cannabis is deemed appropriate.\n\ndrelkind\n_____________________\nI agree with the other answers that say CBD. From the research I've done, CBD can be useful. I found some research here that might be useful, as well as some more medical studies from NCBI. \n\njudahhanh\n_____________________\n Are you depressed, suffering from cancer,seizure,Anxiety,Panic  attack,Depression, diabetes, glaucoma, headache, insomnia, joint pains,  multiply sclerosis, muscle spasms, nausea, etc and need the best strains  of medical marijuana and Cbd Oil to help ease your pain?? why not try  out our wide range of products today at:( tplug05 at gmail dot com) \n\nalison leton","image":null}}]}},"pageContext":{"limit":12,"skip":0,"numPages":1,"currentPage":1,"id":4936,"name":"Alzheimer's Disease","slug":"alzheimer's-disease","country":"US"}},"staticQueryHashes":["3949754563","4179947113","4202924991"]}