{"componentChunkName":"component---common-build-question-tags-template-js","path":"/question-tag/dosage/","result":{"data":{"allQuestion":{"edges":[{"node":{"id":"Question_12363-markdown","title":"Any advice for using CBD for helping to improve Hashimotos? What’s the recommended daily dose?   ","slug":"any-advice-for-using-cbd-for-helping-to-improve-hashimotos-what-s-the-recommended-daily-dose","content":"\"I’ve seen vapour devices, are these more superior in delivery than liquid drops\"\n_____________________\nHi there!\n\nIn a 2015 cross sectional analysis study designed to assess  the relationship between marijuana and thyroid function, researchers  found that \"cannabis had a weak but statistically significant inverse  correlation between recent marijuana use and the thyroid antibodies TPOAb  and TBGAb, while free T3 showed a significant positive correlation.\"  Or, in other words, cannabis use correlated to decreased levels of thyroid-attacking  antibodies, and higher levels of T3, suggesting that recent cannabis use improved thyroid function via reducing thyroid autoimmunity — several  studies have demonstrated cannabis' immunomodulatory  properties — and  either a direct or indirect positive effect on T3 levels. \nhttp://abstracts.eurospe.org/hrp/0084/hrp0084P3-1183\n\nIn a similar study, researchers \"showed that recent marijuana users had significantly lower frequency of elevated thyrotropin (TSH) and positive anti-thyroperoxidase antibody  (TPOAb) versus nonusers/past users.\"\nhttps://www.ncbi.nlm.nih.gov/pubmed/27799014\n\n\ndrkim\n_____________________\n\nFurthermore, in a 2009 preclinical study, researchers found that the  type 1 cannabinoid  receptor 1 (CB1) was densely present on both  excitatory and inhibitory inputs on TRH (thyroid releasing hormone)  neurons, suggesting that the  endocannabinoid system may help regulate  the appropriate manufacturing and secretion of the thyroid hormones, T3  and T4. This also makes sense, since the endocannabinoid system (ECS) is  largely devoted to maintaining homeostasis (the tendency of organisms  to auto-regulate and maintain their internal environment at  equilibrium).\nhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630898\n\nAs of yet, there are no clinical studies evaluating CBD's or THC's specific effects on thyroid function. However, I would hypothesize that CBD would reduce the body's self-attack on the thyroid/ reduce circulating thyroid antibodies, but would have less, if any, of a direct effect on the manufacturing and secretion of thyroid hormone. CBD has been shown to have profound immunomodulatory properties. However, CBD does not meaningfully interact with the CB1 receptor, and thus, would not directly affect thryroid releasing hormone neurons in the method described in the above 2009 study. \n\n\n\ndrkim\n_____________________\nAs far as dosage goes: In general, I would recommend between 10 and 20 milligrams of CBD twice per day. \nFor  Hashimoto's (and most chronic conditions without acute symptoms) I  generally recommend an oil or edible over inhalation methods.\n\nhttps://www.hellolift.com/products/5b57b4c702f1740001523089/cured-full-spectrum-raw-oil\ncontains about 0.83mg of CBD/drop: take 12 drops (10mg) to 23 drops (20mg) twice/day.\n\nhttps://www.hellolift.com/products/5b57a71f02f1740001522f78/cbd-hemp-oil-capsules\n1 pill (15mg) twice per day.\n\nPlease  consult with your physician before starting any cannabis regimen. Do  not discontinue your thyroid medication before consulting with your  prescribing physician.\n\ndrkim","image":null}},{"node":{"id":"Question_12357-markdown","title":"What are products for seniors that have insomnia, depression, anxiety?","slug":"what-are-products-for-seniors-that-have-insomnia-depression-anxiety","content":"\"I am tring to get off of clinical meds, which I have low tolerance for and onto cannabis, which I seem to need a high dose of for sedation.  I am concerned that high indica THC product would make me feel more of what I already feel.\"\n_____________________\n \nHi there! \nRestoring  activity in serotonin  pathways—by increasing the serotonin available  to bind the 5-HT1A receptor in the brain—is how SSRIs  (Selective   Serotonin Reuptake Inhibitors) are thought to alleviate anxiety and    depression. Similarly, several recently published studies suggest  that  CBD does the same. However, CBD does so, not by increasing the   serotonin available to bind 5-HT1A receptors, as SSRIs do, but by   mimicking serotonin's action at the 5-HT1A receptor; or, in scientific   terms: CBD is a 5-HT1A  receptor agonist. ++\n\nIn  general, for anxiety and depression issues, patients take between 5mg  to 20mg of CBD two to three times/day. However, if possible, adding a  small to moderate amount of THC would be much more effective, especially  during any acute increase of intense anxiety—2.5mg to 10mg of THC is  what most patients find helpful, without unwanted side effects. However,  patients should always \"start low, and go slow.\" So, patients should  not start above 2.5mg of THC. ++ If THC is available, it can be mixed  with THC at varying levels. These products are expressed in ratios. ++ Ratios: In the vast majority of cases, are expressed in Parts of CBD, to every Part of THC.\n\ndrkim\n_____________________\nSo, for example, 10:1 would indicate 10CBD:1THC; 2:1 would indicate 2CBD:1THC\nIn  general, when both CBD and THC are valuable in treating the condition,  it's a good idea to keep the milligrams of CBD relatively consistent,  then manipulate the ratios to provide an appropriate amount of THC. Most  choose between 5 to 20mg of CBD. \n\nSo, for example, if we wanted  to keep the CBD dosage at 10mg, we would choose the ratio of the product  that provides the amount of THC that is acceptable to the patient. Many  patients want no perceptible psychoactivity during the day, while some  psychoactivity during the evening is acceptable. In this situation, many  would use a higher ratio during the day, such as\n10:1, which would  provide 10mg of CBD and 1mg of THC. Most patients do not perceive  psychoactivity when taking 1mg, or less of THC\n\nThen as a sleep  aid, a more balanced ratio, such as 1:1, which would provide 10mg of  CBD, and 10mg of THC. 10mg is considered a \"standard dose.\" Most new  patients report 10mg of THC to be moderately to extremely psychoactive.  So, when starting, it's always a good idea to start low, and go slow.   In general, 2.5mgs of THC would be a good \"test dose.\"\n\ndrkim\n_____________________\nRatios of between 10:1 and 30:1 are rarely  psychoactive, so this ratio-range would be a good choice for most when  psychoactivity is to be avoided, such as during the daytime, or if the  patient prefers to avoid any psychoactivity. +\n\nRatios of between  4:1 and 8:1 are considered mid-range ratios. In general, products in  this range would cause mild psychoactivity, noticeable anxiety relief  and a boosted mood, without feeling \"high\". +\n\n2:1 and 1:1 are  more balanced ratios. In general, this range provides the most pain  relief and is the better choice for sleep issues. +++\n\nOils:\n1. Place the oil under your tongue.\n2. Use your tongue to gently “paint” the tincture around your inner cheeks\n3. Wait 60 to 90 seconds before swallowing.\nEffects should peak in about 15 minutes, and should last between 2 to 4 hours\n\nEDIBLES:\nWait  at least 1 hour to gauge efficacy. When you are on an empty stomach,  peak effect is reached in about one hour. However, if you have had a  large meal, especially a fatty meal, it can take up to two hours to  reach peak effect. Effects should last between 4 to 10 hours.\n\nWhen  choosing products, make sure that the product label specifies the  amount of CBD and/or THC per drop or dropper-full. Many products simply  state the total amount of CBD and/or THC, which leads to unnecessary  confusion. +++\n\ndrkim\n_____________________\nWhen looking for a quality CBD oil, pill or vape cartridge, make sure that they:\n1. Use CO2 extraction\n2. Practice \"Whole plant philosophy\", which should preserve many of the lesser known cannabinoids, terpenes, and flavonoids found in cannabis.  \n3. Use organic  hemp or cannabis \n4.  Clearly labeled bottle, specifying the milligrams of CBD per dose—skip  it if it only indicates the total amount of CBD in the product. \nKeep in mind, that heavy use of THC will lead to the worsening of depression and anxiety. \n\nThere  is no need for specialized products for senior citizens. If used  judiciously, cannabis has a relatively benign side effect profile. \n\nSome quality CBD products:\nhttps://www.hellolift.com/products/5b57a71f02f1740001522f78/cbd-hemp-oil-capsules\nhttps://www.hellolift.com/products/5b57b4c702f1740001523089/cured-full-spectrum-raw-oil\nhttps://www.hellolift.com/products/5bd399485d8e87a60c6a60c3/revive-vape-pen\n\nSome products with THC to consider:\nhttps://www.hellomd.com/products/5ab445285ff2ea000b4e974d/41-soft-gel-capsules\nhttps://www.hellomd.com/products/58068e8323698800071d25a7/calm\nhttps://www.hellomd.com/products/5bb3ca617fa32847af85f528/cbd-chocolate-bar\nhttps://www.hellomd.com/products/5bb3c9cf7fa3280a9585f51a/relax-cbd\n\nI hope this helps!\n\ndrkim","image":null}},{"node":{"id":"Question_12348-markdown","title":"What is most effective product for sedation?","slug":"what-is-most-effective-product-for-sedation","content":"\"I am a 66 year old male, 170 lbs.  I have some health issues including essential hyperteinsion, depression, insomnia. I was diagnosed with MONO in 2016.\n\nFor the past 2 years I have tried medications that were either sleep meds or psychiatric meds to help with sedation.  Some helped for awhile, but my body eventually developed a tolerance.  In general, my tolerance for meds is LOW.\n\nCurrenly I am using a Dosist Sleep Pen at 9 PM and I do get high from 1 dose.  However, by 11 PM, I am still not sleepy at all.\n\nIn the past, I have tried 8:1 and 1:1 CBD Subliminal Tinctures, 18:1 CBD Gel Caps, PLUS Restore Gummies.  None have helped significantly with sedation.\n\nI do my best to be active and work my body.  I do not take any recreational drugs or use any alcohol.  I try to observe sleep hygiene and practice mindfulness.  \n\nMy general health is good.  My PCP examined me last fall.  My current meds include a statin, blood pressure, vitamins, and baby aspirin.  \n\nI am financially stable, have rich history of family and friends, am divorced since 2013.  I am working on lifestyle changes, but it is slow going.  Since 2005 I worked with seniors  in Senior Communities. I have been working on a spiritual practice, recently learning what Ananda has to offer.\n\nAny comments or suggestions are much appreciated.\"\n_____________________\nLook at the strain of cannabis you are using as well.  You should try to aim for an indica strain which has a more of a sedating and relaxing effect.  Sativa is more energizing and better used in the day time.  You should look for a product that has a mid to high range THC (if no contraindications) and I would advise you dose in an oil form as the effect will last longer but of course the onset is much slower than inhalation.  Follow sleep hygiene rules and you don't want to develop a sleep dependency issue with any sleep agents, and lastlly I would advise that you consider a referral for a sleep study from your primary care provider.  \n\nAmyT","image":null}},{"node":{"id":"Question_12327-markdown","title":"Dose your recommendation work for Oklahoma ","slug":"dose-your-recommendation-work-for-oklahoma","content":"\"Oklahoma recommendation \"\n_____________________\nOur recommendation service is available in California and New York within the United States.\n\nFor more information regarding the medical marijuana program in Oklahoma, try here: https://www.marijuanadoctors.com/medical-marijuana/ok/\n\nKevin P.","image":null}},{"node":{"id":"Question_12320-markdown","title":"Struggling with side effects","slug":"struggling-with-side-effects","content":"\"I was instructed by my psychiatrist to start CBD oil on top of my Cymbalta because I can’t tolerate going up anymore on the dosage. First weeks of using CBD from reparable brands I felt great. Lifted my mood, gave me energy, could take multiple dosages of it a day and felt fine. But now it’s making me really sleepy, even at low dosages, I’m talking about less than 5 mg here. I take it sublingually. It’s full spectrum CBD too. If I stop taking it, the low mood will start coming back, so it is working for that but the triedness is becoming a problem. It was working so good that I felt like I’d be able to reduce my antidepressant one day. Now I feel I can’t tolerate the CBD oil. Btw, if I take it at night, I either have where I’m tired the next day or sometimes (and this is the weirdest thing) it’ll wake me up. Still is all very frustrating. \"\n_____________________\nHi there! I think it would be a great idea to discuss your experience, and tapering off of the Cymbalta, with your psychiatrist.  I would also be glad more than glad to help. But, in the meantime, it would be best to reserve the CBD for the evening, and/or reduce the dosage amount and frequency. I hope this helps!\n\ndrkim","image":null}},{"node":{"id":"Question_12309-markdown","title":"What cbd product might i take for seizures","slug":"what-cbd-product-might-i-take-for-seizures","content":"\"Have been diagnosed with seizure activity that is mild (absentee seizures). I take Keppra for this. My doctor here in Arkansas said I could also take some cbd product to help. Since cbd is new to Arkansas my Dr. had no advice as to dosage or brand of cbd product. His advice was basically to experiment like it was a dietary supplement from WALMART. Do you have any information that might help me find out what cbd product might be good for me?\"\n_____________________\nHello and thank you for your question,\nCannabis is now very well  known for it's efficacy as an anti-epileptic medication. In fact, the  walk in clinic I also work at receives several referrals from the  neighboring Children's Hospital for their seizure patients; I myself  have treated patients as young as three.\n\nThe story that really  put cannabis in the spotlight as an effective anti-epilectic was the  story of Charlotte Figi, a beautiful child who was suffering from up to  300 grand mal seizure per week! She was eventually treated with a cbd  oil which reduced her seizure frequency down to two to three times per  month; that's about a 99% improvement! That cbd oil that was eventually  branded as Charlotte's Web.\n\nTherefore, I would recommend a cbd  oil to ingest as daily prevention while also carrying a pen vaporizer  loaded with a cbd cartridge to use if you experience an aura - i.e. a sensory warning that a seizure is about to occur. I recommend a vape pen  in the above scenario since a vape pen is the quickest delivery method  available. Therefore, when/if you experience an aura, you could  hopefully get a dose in before the seizure starts.\n\ndrkim\n_____________________\nExcellent CBD oils:\nhttps://www.hellolift.com/products/5b57a95202f1740001522f9f/cbd-hemp-oil-drops\nhttps://www.hellolift.com/products/5b57b4c702f1740001523089/cured-full-spectrum-raw-oil\nExcellent CBD vapes:\nhttps://www.hellolift.com/products/5bb53ed015dd427039a0a351/relax-vape-pen\nhttps://www.hellolift.com/products/5b5770d702f1740001522c60/cbd-aches\nI hope this helps!\n\ndrkim","image":null}},{"node":{"id":"Question_12302-markdown","title":"if I have a bottle of cooking oil that says 6400 of THC was used to make 60ml of cooking oil what is the dose per cookie?","slug":"if-i-have-a-bottle-of-cooking-oil-that-says-6400-of-thc-was-used-to-make-60ml-of-cooking-oil-what-is-the-dose-per-cookie","content":"\"THC infuse cooking oil\n\"\n_____________________\nDosing with oils can be tricky which is why we prescribe it via mls despite the mg/g concentration on the bottle.  In regards to your question if you are talking about 6400mg of THC in 60mls of oil that would simply equal approx 106mg per ml.  Of course depending on the recipe and cooking method, it would be difficult to tell how much THC would be in each edible product.  Thus for precise dosing you would prefer direct absorption of an oil or capsule instead of putting it in an edible product.  Hope that helps!\n\nAmyT","image":null}},{"node":{"id":"Question_12293-markdown","title":"What is the most accurate dose of CBD/THC for stage 4 Hodgkin’s lymphoma?","slug":"what-is-the-most-accurate-dose-of-cbdthc-for-stage-4-hodgkins-lymphoma","content":"\"wh is the most accurate dose of CBD/THC for stage 4 Hodgkin’s lymphoma cancer \"","image":null}},{"node":{"id":"Question_12247-markdown","title":"My wife would like to try CBD oils as part of her diabetes (type 2) treatment.  Can you recommend a product and dosage?  My on line research gave me a very margine for dosage.  Thank you in advance for any help you can give!","slug":"my-wife-would-like-to-try-cbd-oils-as-part-of-her-diabetes-type-2-treatment-can-you-recommend-a-product-and-dosage-my-on-line-research-gave-me-a-very-margine-for-dosage-thank-you-in-advance-for-any-help-you-can-give","content":"\n_____________________\nHi there!\nThere  was a very recently published randomized, double-blind,   placebo-controlled study (the gold-standard of study design) which found that in humans:\n- THCV  significantly decreased fasting plasma glucose and improved pancreatic β-cell (insulin secreting cell) function\n- CBD reduced a hormone called resistin, which has been shown to increase LDL (bad cholesterol)\n-CBD   increased glucose-dependent-insulinotropic peptide, which is a hormone  that enhances the release of insulin following the intake of food. \nhttps://www.ncbi.nlm.nih.gov/pubmed/27573936\nFor more information on THCV:\nhttps://www.hellomd.com/health-wellness/5a8db389f24d1300077ccb5a/psychoactive-thcv-the-cannabinoid-that-kills-your-appetite\n\nFurthermore, prolonged administration of THC, in both humans and   experimental animals, results in the lowering of both blood pressure and  heart rate. Animal studies suggest that this may be due to  a reduction in  adrenergic tone, which is also how beta-blockers, such  as metoprolol, work as anti-hypertensives. \nhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228270/#R11\nAlso, a study published last year found that a 600mg dose of CBD reduced   blood  pressure while resting, as well as when under physical or mental  stress. \n https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470879/#B7\nDiabetes raises the risk of heart disease, stroke, kidney disease and other  health problems; high blood pressure significantly raises those risks.\n\ndrkim\n_____________________\n***You should inform your primary care physician about your plan to try cannabis as an adjunct to your current medication(s)—cannabis should be used as an adjunct to your current medications unless your primary care physician approves otherwise; it would be a good idea to compare your post-meal blood glucose with and without the CBD product—meaure blood glucose two hours after a meal. \n\nCare By Design offers several different delivery methods, offered in  multiple ratios; they also exclusively carry \"whole plant\" products.\nhttps://www.projectcbd.org/science/cannabis-pharmacology/single-compound-vs-whole-plant-cbd\nThe 18:1 products at https://www.cbd.org/ would be a great choice.\n\nhttps://www.hellomd.com/products/58ed54d1c064b41c99fad29e/181-sublingual-drops\nhttps://www.cbd.org/products/drops/18-1-drops\n- Each drop contains 0.38mg of CBD and 0.02mg of THC. \n- take 25 drops (10mg  CBD, 0.5mgTHC) about 20minutes before each meal. \n\nhttps://www.hellomd.com/products/58ed6e9863d9e92638368c9d/181-soft-gel-capsules-10-mg\nhttps://www.cbd.org/products/soft-gels/18-1-soft-gels\n- take one tab (10mg  CBD, 0.5mgTHC) about 20 minutes before each meal.\n\nOtherwise, with any other CBD or high CBD/low THC product,\n- take 10mg of CBD about 20 minutes before each meal. \n\nI hope this helps!\n\nhttps://www.youtube.com/watch?v=Y_G4OqWxgys\n\n\ndrkim","image":null}},{"node":{"id":"Question_12242-markdown","title":"Trying to wean off heroin  ","slug":"trying-to-wean-off-heroin","content":"\"Currently taking 450 mg hemp oil with 38.5 mg CBD twice daily.  Trying to find a doctor to work with me but that is proving difficult.  Where can I find dosages, doctors, guidance and  anyone who has gone this route and succeeded.  \"\n_____________________\nHello,\nI'm  glad to hear of your willingness to take steps  towards sobriety.  However, overcoming a heroin addiction is a complex  and arduous task.  We can help with ameliorating some of the unpleasant symptoms of opiate withdrawal. However, it would be medical malpractice to work as the primary physician for what should be  a multi-modal treatment strategy led by a physician with specialized  training in addiction medicine.\n\nSymptoms of opiate withdrawal may include: muscle aches,  restlessness, anxiety, runny nose, sweating, insomnia, abdominal  cramping, diarrhea,  nausea and vomiting. Cannabis should help alleviate pain, anxiety,  insomnia, restlessness and nausea; these issues are best treated with a decent amount of THC. Accordingly, I would likely discourage, unless the patient were averse to THC, using a Very high CBD vs low THC   product, nor would I recommend Very high CBD strains in this situation.\n\ndrkim\n_____________________\nHere are products and strains for you to consider:\n1. https://www.cbd.org/products/chocolates/1-1-chocolate - a \"whole plant\" 2:1 edible\n2. http://dosist.com/pen-relief/ - a 1:2 vaporizer pen\n3. http://kivaconfections.com/products/bars/ginger - a 1:1 \"whole plant\" edible\n\nSome CBD strains to consider: \nSweet and Sour Widow - a 1:1 indica strain \nPennywise - a 1:1 indica strain \nCannatonic - a 3:1 hybrid strain\n\nSome \"standard\" strains to consider (indica or indica dominant hybrids):\nGrand Daddy Purp\nNorthern Lights\nGod's Gift\nChocolate Chunk\n\nFor more detailed and customized recommendations, you can set up an appointment by clicking on the \"Doctor's Consult\" at www.hellomd.com\n\nI hope this helps some, and best of luck!\n\ndrkim","image":null}},{"node":{"id":"Question_12212-markdown","title":"Looking for dosing options and / or Dr. who will work with a heroin addict to wean off with CBD.  ","slug":"looking-for-dosing-options-and-or-dr-who-will-work-with-a-heroin-addict-to-wean-off-with-cbd","content":"\"Addict has been using CBD twice a day for a few weeks and now is ready to start weaning off of herion.  Need help in actual dosing and increments that are best.  Also what to expect. Tried looking up doctors in our area who would treat addiction with CBD but was unsuccessful.  \"\n_____________________\nHello,\nI'm glad to hear of your willingness to take steps  towards sobriety. However, overcoming a heroin addiction is a complex  and arduous task. We can help with ameliorating some  of the unpleasant symptoms of opiate withdrawal. However, it would be  medical malpractice to work as the primary physician, for what should be  a multi-modal treatment strategy led by a physician with specialized  training in addiction medicine. \n\nSymptoms of opiate withdrawal may include: muscle aches,  restlessness,  anxiety, runny nose, sweating, insomnia, abdominal  cramping, diarrhea,  nausea and vomiting. Cannabis should help alleviate  pain, anxiety,  insomnia, restlessness and nausea; these issues are best treated with a  decent amount of THC. Accordingly, I would likely discourage, unless   the patient were averse to THC, using a Very high CBD vs low THC  product, nor would I recommend Very high CBD strains in this situation.   \n\ndrkim\n_____________________\nHere are products and strains for you to consider:\n1. https://www.cbd.org/products/chocolates/1-1-chocolate - a \"whole plant\" 2:1 edible\n2. http://dosist.com/pen-relief/ - a 1:2 vaporizer pen\n3. http://kivaconfections.com/products/bars/ginger - a 1:1 \"whole plant\" edible\n\nSome CBD strains to consider: \nSweet and Sour Widow - a 1:1 indica strain \nPennywise - a 1:1 indica strain \nCannatonic - a 3:1 hybrid strain\n\nSome \"standard\" strains to consider (indica or indica dominant hybrids):\nGrand Daddy Purp\nNorthern Lights\nGod's Gift\nChocolate Chunk\n\nI hope this helps some, and best of luck!\n\n\ndrkim\n_____________________\nI'd like to second Dr. Kim's point about the complexity of managing opioid withdrawal, not to discourage it but to be realistic about what is involved.  Of course, the severity and duration of the symptoms will depend on the level of addiction, which we do not know.  While cannabis can be helpful, I'm fairly sure that CBD alone, or even with generous amounts of THC, will not be sufficient to ameliorate significant withdrawal symptoms.  A variety of non-opioid prescription medications such as clonidine can be extremely helpful in this situation, so I strongly encourage you to keep searching for a medical situation for managing the acute withdrawal phase. \n\ndrelkind","image":null}},{"node":{"id":"Question_12086-markdown","title":"What happens if you take a very large dose of CBD? 10000mg? 20000mg?","slug":"what-happens-if-you-take-a-very-large-dose-of-cbd-10000mg-20000mg","content":"\n_____________________\nHi there!\nThe side effect profile of CBD is as benign as any medication I can think of. In  fact, in a comprehensive review of 132 studies, researchers found that  CBD, at several different dosages, did not adversely affect vital signs,  psychological function, motor function and did not produce toxic metabolites. However, there were no studies which surpassed dosages of  over 1500mg/day. I do not recommend that you experiment with taking  mega-doses of CBD, or anything for that matter.\nHope this helps!\nhttps://www.medicinalgenomics.com/wp-content/uploads/2013/01/Bergamaschi_2011.pdf\n\ndrkim\n_____________________\n There is no known lethal dose of CBD in humans. It has apparently been fatal in monkeys at a dose of 200 mg/kg, which for a normal male human would be about 14,000 mg. But I wouldn't suggest trying to check it out. If you do take any prescription medications, 10,000 mg of CBD could be a sufficient dose to interefere with the metabolism of many of them. Otherwise, I'd mostly bet on some nausea and diarrhea. There are also essentially no reports of specific organ toxicity of CBD, but taking that much at one time of any biologically active substance could easily be toxic in ways that are not at all relevant in the reasonable dosage range. \n\ndrelkind","image":null}}]}},"pageContext":{"limit":12,"skip":0,"numPages":15,"currentPage":1,"id":5206,"name":"Dosage","slug":"dosage","country":"US"}},"staticQueryHashes":["3949754563","4179947113","4202924991"]}