{"componentChunkName":"component---common-build-question-tags-template-js","path":"/question-tag/ibs/","result":{"data":{"allQuestion":{"edges":[{"node":{"id":"Question_12316-markdown","title":"Can CBD help with GI issues? ","slug":"can-cbd-help-with-gi-issues","content":"\"Specifically IBS, IBD, and GERD?\"\n_____________________\nHi there!\n\nThe endocannabinoid system (ECS) is largely devoted to maintaining homeostasis (the tendency of organisms to auto-regulate and maintain their internal environment at equilibrium). Deficiency or malfunction of the ECS has become a focus for researchers seeking treatment options for several maladies—especially those that have few, if any, effective pharmocotherapeutic interventions, such as celiac disease, MS, fibromyalgia, IBD and IBS. In fact, the scientific community has recently termed the ECS malfunction: Clinical Endocannabanoid Decifiency, or CEDC. CBD works by balancing and supporting the ECS through its subtle effects on cannaboinoid receptor-1 (CB1) and cannaboinoid receptor-2 (CB2) receptors, as well as other receptors that modulate serotonin, GABA, dopamine, and many more.\nIn IBD and GERD, inflammation is central to both the etiology and symptomology of the respective disease. CBD is well known as an effective immunomodulator and anti-inflammatory, and those properties still do apply to GI inflammation. However, unique to the GI tract, are specialized nerve cells called enteric glial cells— \"the glue of the nteric nervous system (ENS)\"—which, when overactive, also contribute to acute and chronic GI inflammation. Recent pre-clinical research suggests that CBD may lower GI inflammation by controlling reactive gliosis in the ENS. Or, in other words, CBD restores homeostasis in the gut by reducing hyperactivity in enteric glial cells.\n\ndrkim\n_____________________\nThe ENS is an extensive network of neurons supported by enteric glial cells (the above mentioned \"glue\" on the ENS). Two neural plexuses comprise the ENS: the myenteric plexus, involved in motility/peristalsis; and the submucosal plexus, involved in intestinal and gastric secretions. CBD works to restores homeostasis in the ENS via modulation of enteric glial cells (as mentioned above), the myenteric plexus, and the submucosal plexus.\n\nAlthough inflammation plays little, if any, role in the pathology of IBS, CBD's balancing of the myenteric plexus lessens inappropriate and painful intestinal contractions; while balancing of the submucosal plexus reduces inappropriate gastric and intestinal secretions. CBD's effects on glial cells, the submucosal plexus and myenteric plexus factor into CBD's ability to alleviate symptoms of GERD, IBS and IBD.\n\nAn ongoing, randomized, placebo controlled, double-blind, cross-over trial has shown chewable CBD to significantly reduce IBS-related pain. To be included in the study, it was also necessary that patients experienced, according to their own account, at least three pain episodes per week of a predefined intensity. All patients who participated in the study experienced decrease in their levels of pain score. On top of the overall reduction, the trend curve suggests 50% higher pain reduction.\n\ndrkim\n_____________________\nFurthermore, several studies show that among patients who seek medical attention for IBS or IBD, around 70% of IBS patients, and 30% of IBD patients, have psychiatric comorbidity—depression and generalized anxiety disorder being most common. CBD increases serotonin signaling at the 5-HT1A receptor—the same neurotransmitter and receptor that SSRIs like Prozac influence—which is mostly why CBD has antidepressant and anxiolytic properties. In fact, SSRIs and tricyclic antidepressants (which also increase serotonin signalling), have been shown to alleviate anxiety and depression symptoms, as well as alleviate some of the abdominal pain and bowel symptoms involved in IBS, IBD and gastroesophageal reflux disease (GERD), which is why SSRIs and TCAs are commonly prescribed for IBS and IBD.\n\nI hope this helps!\n\ndrkim","image":null}},{"node":{"id":"Question_12315-markdown","title":"Can CBD help with GI issues?","slug":"can-cbd-help-with-gi-issues-1","content":"\"Like IBS, IBD and GERD?\"\n_____________________\nHi there!\nThe endocannabinoid system (ECS) is largely devoted to maintaining homeostasis (the tendency of organisms to auto-regulate and maintain their internal environment at equilibrium). Deficiency or malfunction of the ECS has become a focus for researchers seeking treatment options for several maladies—especially those that have few, if any, effective pharmocotherapeutic interventions, such as celiac disease, MS, fibromyalgia, IBD and IBS. In fact, the scientific community has recently termed the ECS malfunction: Clinical Endocannabanoid Decifiency, or CEDC. CBD works by balancing and supporting the ECS through its subtle effects on cannaboinoid receptor-1 (CB1) and cannaboinoid receptor-2 (CB2) receptors, as well as other receptors that modulate serotonin, GABA, dopamine, and many more.\n\nIn IBD and GERD, inflammation is central to both the etiology and symptomology of the respective disease. CBD is well known as an effective immunomodulator and anti-inflammatory, and those properties still do apply to GI inflammation. However, unique to the GI tract, are specialized nerve cells called enteric glial cells— \"the glue of the enteric nervous system (ENS)\"—which, when overactive, also contribute to acute and chronic GI inflammation. Recent pre-clinical research suggests that CBD may lower GI inflammation by controlling reactive gliosis in the ENS. Or, in other words, CBD restores homeostasis in the gut by reducing hyperactivity in enteric glial cells.\n\ndrkim\n_____________________\nThe enteric ENS is an extensive network of neurons supported by enteric glial cells (the above mentioned \"glue\" on the ENS). Two neural plexuses comprise the ENS: the myenteric plexus, involved in motility/peristalsis; and the submucosal plexus, involved in intestinal and gastric secretions. CBD works to restores homeostasis in the ENS via modulation of enteric glial cells (as mentioned above), the myenteric plexus, and the submucosal plexus.\n\nAlthough inflammation plays little, if any, role in the pathology of IBS, CBD's balancing of the myenteric plexus lessens inappropriate and painful intestinal contractions; while balancing of the submucosal plexus reduces inappropriate gastric and intestinal secretions. CBD's effects on glial cells, the submucosal plexus and myenteric plexus factor into CBD's ability to alleviate symptoms of GERD, IBS and IBD.\n\nAn ongoing, randomized, placebo controlled, double-blind, cross-over trial has shown chewable CBD to significantly reduce IBS-related pain. To be included in the study, it was also necessary that patients experienced, according to their own account, at least three pain episodes per week of a predefined intensity. All patients who participated in the study experienced decrease in their levels of pain score. On top of the overall reduction, the trend curve suggests 50% higher pain reduction.\n\ndrkim\n_____________________\nFurthermore, several studies show that among patients who seek medical attention for IBS or IBD, around 70% of IBS patients, and 30% of IBD patients, have psychiatric comorbidity—depression and generalized anxiety disorder being most common. CBD increases serotonin signaling at the 5-HT1A receptor—the same neurotransmitter and receptor that SSRIs like Prozac influence—which is mostly why CBD has antidepressant and anxiolytic properties. In fact, SSRIs and tricyclic antidepressants (which also increase serotonin signalling), have been shown to alleviate anxiety and depression symptoms, as well as alleviate some of the abdominal pain and bowel symptoms involved in IBS, IBD and gastroesophageal reflux disease (GERD), which is why SSRIs and TCAs are commonly prescribed for IBS and IBD.\n\nI hope this helps!\n\ndrkim","image":null}},{"node":{"id":"Question_12308-markdown","title":"Can CBD help manage Irritable Bowel Syndrome (IBS)?","slug":"can-cbd-help-manage-irritable-bowel-syndrome-ibs","content":"\"Thank you!\"\n_____________________\nHi there!\nYes it can. It all boils to the endocannabinoid system  (ECS). The ECS is largely devoted to maintaining homeostasis (the  tendency of organisms to auto-regulate and maintain their internal  environment at equilibrium). Deficiency or malfunction of the ECS has  become a focus for researchers seeking treatment options for several  maladies—especially those that have few, if any, effective  pharmocotherapeutic interventions, such as celiac disease, MS,  fibromyalgia, IBD and IBS. In fact, the scientific community has  recently termed the ECS malfunction: Clinical Endocannabanoid  Decifiency, or CEDC.\n\nCBD works by balancing and supporting the  ECS through its subtle effects on cannaboinoid receptor-1 (CB1) and  cannaboinoid receptor-2 (CB2) receptors, as well as other receptors that  modulate serotonin, GABA, dopamine, and many more.\n\nIn IBS, IBD  and GERD, like most every physical-chronic condition, inflammation is  central to both the etiology and symptomology of the respective disease.  CBD works to reduce inflammation by restoring balance to the ECS.\n\ndrkim\n_____________________\nThe main culprit for acute and chronic inflammation in the gut is  hyperactive enteric glial cells, which proliferate and release  neurotrophins, growth factors, and pro-inflammatory cytokines that may  overamplify the immune response. Recent pre-clinical research suggests  that CBD may lower GI inflammation by controlling reactive gliosis in  the enteric (GI) nervous system. Or, in other words, CBD restores  homeostasis in the gut by reducing hyperactivity in enteric glial cells.\n\nFurthermore,  several studies show that among patients who seek medical attention for  IBS or IBD, around 70% of IBS patients, and 30% of IBD patients, have  psychiatric comorbidity—depression and generalized anxiety disorder  being most common. CBD increases serotonin signaling at the 5-HT1A  receptor—the same neurotransmitter and receptor that SSRIs like Prozac  influence—which is mostly why CBD has antidepressant and anxiolytic  properties. In fact, SSRIs and tricyclic antidepressants (which also  increase serotonin signalling), have been shown to alleviate anxiety and  depression symptoms, as well as alleviate some of the abdominal pain  and bowel symptoms involved in IBS, IBD and gastroesophageal reflux  disease (GERD), which is why SSRIs and TCAs are commonly prescribed for  IBS and IBD.\n\nI hope this helps!\n\ndrkim","image":null}},{"node":{"id":"Question_12307-markdown","title":"Can CBD help with Irritable Bowel Syndrome (IBS)?","slug":"can-cbd-help-with-irritable-bowel-syndrome-ibs","content":"\"Thank you!\"\n_____________________\nHi there!\n\nYes it can. It all boils to the endocannabinoid system (ECS). The ECS is largely devoted to maintaining homeostasis (the tendency of organisms to auto-regulate and maintain their internal environment at equilibrium). Deficiency or malfunction of the ECS has become a focus for researchers seeking treatment options for several maladies—especially those that have few, if any, effective pharmocotherapeutic interventions, such as celiac disease, MS, fibromyalgia, IBD and IBS. In fact, the scientific community has recently termed the ECS malfunction: Clinical Endocannabanoid Decifiency, or CEDC. \n\nCBD works by balancing and supporting the ECS through its subtle effects on cannaboinoid receptor-1 (CB1) and cannaboinoid receptor-2 (CB2) receptors, as well as other receptors that modulate serotonin, GABA, dopamine, and many more. \n\nIn IBS, IBD and GERD, like most every physical-chronic condition, inflammation is central to both the etiology and symptomology of the respective disease. CBD works to reduce inflammation by restoring balance to the ECS. \n\ndrkim\n_____________________\nThe main culprit for acute and chronic inflammation in the gut is hyperactive enteric glial cells, which proliferate and release neurotrophins, growth factors, and pro-inflammatory cytokines that may overamplify the immune response. Recent pre-clinical research suggests that CBD may lower GI inflammation by controlling reactive gliosis in the enteric (GI) nervous system. Or, in other words, CBD restores homeostasis in the gut by reducing hyperactivity in enteric glial cells. \n\nFurthermore, several studies show that among patients who seek medical attention for IBS or IBD, around 70% of IBS patients, and 30% of IBD patients, have psychiatric comorbidity—depression and generalized anxiety disorder being most common. CBD increases serotonin signaling at the 5-HT1A receptor—the same neurotransmitter and receptor that SSRIs like Prozac influence—which is mostly why CBD has antidepressant and anxiolytic properties. In fact, SSRIs and tricyclic antidepressants (which also increase serotonin signalling), have been shown to alleviate anxiety and depression symptoms, as well as alleviate some of the abdominal pain and bowel symptoms involved in IBS, IBD and gastroesophageal reflux disease (GERD), which is why SSRIs and TCAs are commonly prescribed for IBS and IBD.\n\nI hope this helps!\n\ndrkim","image":null}},{"node":{"id":"Question_11906-markdown","title":"I have terrible IBS and want to know if CBD may help with intestinal issues?","slug":"i-have-terrible-ibs-and-want-to-know-if-cbd-may-help-with-intestinal-issues","content":"\"I'm not interested in being high, but someone told me that CBD may be able to help me.\"\n_____________________\nThere is far more reason to try CBD than not to.  There are interesting laboratory science reports showing possible ways it may be helpful, and anecdotal reports of benefit in IBS, along with virtually no reports of adverse effects.  You may find through experimentation that varying the CBD:THC ratio of the preparation you are using may lead you to the most beneficial formula for your symptoms.  Good luck.\n\ndrelkind\n_____________________\nHello,\nActivating cannabinoid receptors has been shown to  inhibit  gastrointestinal fluid secretion and inflammation in animal  models.  Several studies indicate that cannabinoids in marijuana bind  with  cannabinoid receptors in the digestive tract, especially the small  and  large intestine.\n\nFurthermore, both CBD and THC have been  shown  to reduce the inflammatory response in patients with autoimmune   diseases, such as multiple sclerosis, lupus and celiac disease; both CBD   and THC have  also been shown to help alleviate pain.\n\n\"CBD may  interact at extra-cannabinoid system  receptor sites, such as   peroxisome proliferator-activated  receptor-gamma. This strategic   interaction makes CBD as a potential  candidate for the development of a   new class of anti-IBD drugs.\"\nhttps://www.ncbi.nlm.nih.gov/pubmed/22815234\n\n\"CBD   targets enteric reactive gliosis, counteracts the inflammatory   environment ... in human colonic cultures derived from UC patients.   These actions lead to a reduction of intestinal damage. Our results   therefore  indicate that CBD indeed unravels a new therapeutic strategy   to treat  inflammatory bowel diseases.\" \nhttp://journals.plos.org/plosone/article?id=10.1371/journal.pone.0028159\n\ndrkim","image":null}},{"node":{"id":"Question_8352-markdown","title":"What strains will help emotionally unstable personality disorder?","slug":"what-strains-will-help-emotionally-unstable-personality-disorder","content":"\n_____________________\nCannabis could potentially worsen or exacerbate psychiatric symptoms, especially strains that are higher in THC. It would be best to try strains that are higher in CBD. It would be important to consult with a psychiatrist and inform them if you're using cannabis and it is very important to be monitored closely. We do not recommend stopping your psychiatric medication while using cannabis.\n\njulienp","image":null}},{"node":{"id":"Question_8087-markdown","title":"vape pen for ibs","slug":"vape-pen-for-ibs","content":"","image":null}},{"node":{"id":"Question_7658-markdown","title":"Does irritable bowel syndrome (IBS) respond to cannabis?","slug":"does-irritable-bowel-syndrome-ibs-respond-to-cannabis","content":"\n_____________________\nYes! Absolutely. And it is one of the qualifying conditions for the NYS MMJ Program. The effectiveness of cannabis for treating IBS is vastly known. Many of those suffering from IBS report that abdominal pain, nausea, cramping and irregularity of bowel movements are  alleviated with the use of medical cannabis. \n\nResearch shows that medical cannabis can improve motility, calm spasms, and provide pain relief. Cannabinoids play crucial roles in controlling the motility and inflammation of the gastrointestinal system. A study conducted in Italy in 2003 found that THC, the most common cannabinoid known for its strong psychoactive properties, reduced intestinal motility, thereby alleviating colonic spasms and abdominal pain.\n\ntatiananp","image":null}},{"node":{"id":"Question_7008-markdown","title":"Can I get a MMJ card with a diagnosis of IBS? ","slug":"can-i-get-a-mmj-card-with-a-diagnosis-of-ibs","content":"\n_____________________\nIf you reside in California, the answer is yes.  After speaking with a doctor, feel free to reach out to us as we have worked with many patients with a similar diagnosis. Most people experience relief through cannabis so there is hope.\n\ndneice\n_____________________\nYou can definitely get a recommendation for IBS. Cannabis has proven to be a phenomenal deterrent for IBS. You can get your recommendation here on HelloMD and then shop online with us at Green Door West, we'll deliver right to your doorstep! You can find our menu and delivery area here: https://greendoorwest.com/collections.\n\ngreendoorwest","image":null}},{"node":{"id":"Question_10748-markdown","title":"Can cannabis be used for constipation and bloating related to IBS?","slug":"can-cannabis-be-used-for-constipation-and-bloating-related-to-ibs","content":"\"I have IBS and ulcerative colitis with bloating and constipation. Do you have a marijuana recommendation for immediate relief as well as something that may be preventative?\"\n_____________________\nSublingual tinctures are the most effective way to use CBD oil.\n\nCare By Design has some very good sublingual sprays that a friend of mine uses - I will link them below!\n\nhttps://www.cbd.org/products\n\nryanscherer\n_____________________\nInteresting question! Constipation is a common ailment in the United States and there are several medical conditions associated with it; however, constipation is usually attributed to a low fiber diet, low water intake, and lack of physical activity. If you have long term constipation that is not alleviated by basic measures, it is important that you see your physician to rule out any underlying diseases. \n\nIt turns out that cannabis has been used for thousands of years to alleviate constipation. Cannabis has anti-emetic and anti-spasmodic properties and may relax your bowels. Hemp seed oil is used in China as a laxative. Around 2300 B.C., Emperor Sheng Nung prescribed marijuana for this and several other purposes. Ayurvedic physicians in India mix hemp leaves with milk, spices, and sugar for constipation. Tincture of cannabis was sold over the counter in the United States until 1937. \n\nIngestible forms of cannabis logically may be more beneficial for constipation, although any systemic route of administration (tinctures, vapor) may help.\n\ndredmunds\n_____________________\nEveryone is different, so in dosing I would start low and increase the dose as tolerated. I would also recommend a whole plant cannabis extract that uses the female flowers of CBD rich cananbis plants. This hemp extract is derived from the seeds and stalks of mature industrial hemp plants. This extract does not provide a high level of CBD. For the price I would not reccomend it.\n\nandrewvanmd\n_____________________\nAbsolutely.  Many men (and women) use Foria Relief rectally for a variety of reasons including low back pain, sciatica, IBS, general GI tract issues and muscle pain.     The anti-spasmodic, anti-inflammatory and pain relieving properties of CBD and THC can help greatly with these issues.\n\nkarin\n_____________________\n\nnurit","image":null}}]}},"pageContext":{"limit":12,"skip":0,"numPages":1,"currentPage":1,"id":5369,"name":"IBS","slug":"ibs","country":"US"}},"staticQueryHashes":["3949754563","4179947113","4202924991"]}