{"componentChunkName":"component---common-build-question-tags-template-js","path":"/question-tag/inflammation/","result":{"data":{"allQuestion":{"edges":[{"node":{"id":"Question_12352-markdown","title":"I’ve recently been diagnosed with Chron’s disease. I’m looking for a daily CBD tinctures to keep inflammation away; which is extremely important for my condition. But a tincture that won’t keep me high all day. More for maintenance. Any suggestions?","slug":"i-ve-recently-been-diagnosed-with-chron-s-disease-i-m-looking-for-a-daily-cbd-tinctures-to-keep-inflammation-away","content":"\"Which CBD tincture is best to eliminate inflammation associated with Chron’s disease?\"\n_____________________\nOur hemp CBD tinctures do not contain THC, so none of them will be psychoactive.\n\nThe most powerful CBD product for inflammation will be the one with the highest concentration of CBD. We are particularly fond of the Wildflower CBD+ tincture, with contains 1000mg of full-spectrum CBD extract: https://www.hellolift.com/products/5b57ae8402f1740001523015/cbd-relief\n\nKevin P.\n_____________________\nThe endocannabinoid system (ECS) is largely devoted to maintaining homeostasis (the tendency of organisms to auto-regulate and maintain their internal environment at equilibrium). Deficiency or malfunction of the ECS has become a focus for researchers seeking treatment options for several maladies—especially those that have few, if any, effective pharmocotherapeutic interventions, such as celiac disease, MS, fibromyalgia and IBD (Crohn's disease and and ulcerative colitis). In fact, the scientific community has recently termed the ECS malfunction \"Clinical Endocannabanoid Decifiency,\" or CECD. CBD works by balancing and supporting the ECS through its subtle effects on cannaboinoid receptor-1 (CB1) and cannaboinoid receptor-2 (CB2) receptors, as well as other receptors that modulate serotonin, GABA, dopamine, and many more.\n\ndrkim\n_____________________\nIn IBD and GERD, inflammation is central to both the etiology and symptomology of the respective disease. CBD is well known as an effective immunomodulator and anti-inflammatory, and those properties still do apply to GI inflammation. However, unique to the GI tract, are specialized nerve cells called enteric glial cells— \"the glue of the nteric nervous system (ENS)\"—which, when overactive, also contribute to acute and chronic GI inflammation. Recent pre-clinical research suggests that CBD may lower GI inflammation by controlling reactive gliosis in the ENS. Or, in other words, CBD restores homeostasis in the gut by reducing hyperactivity in enteric glial cells.\nThe enteric ENS is an extensive network of neurons supported by enteric glial cells (the above mentioned \"glue\" on the ENS). Two neural plexuses comprise the ENS: the myenteric plexus, involved in motility/peristalsis; and the submucosal plexus, involved in intestinal and gastric secretions. CBD works to restores homeostasis in the ENS via modulation of enteric glial cells (as mentioned above), the myenteric plexus, and the submucosal plexus.\n\ndrkim\n_____________________\n\nFurthermore, several studies show that among patients who seek medical attention for IBS or IBD, around 70% of IBS patients, and 30% of IBD patients, have psychiatric comorbidity—depression and generalized anxiety disorder being most common. CBD increases serotonin signaling at the 5-HT1A receptor—the same neurotransmitter and receptor that SSRIs like Prozac influence—which is mostly why CBD has antidepressant and anxiolytic properties. In fact, SSRIs and tricyclic antidepressants (which also increase serotonin signalling), have been shown to alleviate anxiety and depression symptoms, as well as alleviate some of the abdominal pain and bowel symptoms involved in IBS, IBD and gastroesophageal reflux disease (GERD), which is why SSRIs and TCAs are commonly prescribed for IBS and IBD.  \n\nWhen choosing products, make sure that the product label specifies the amount of CBD and/or THC per drop or dropper-full (such as the product Kevin recommended). Many products simply state the total amount of CBD and/or THC, which leads to unnecessary confusion.\n\nI hope this helps!\n\ndrkim","image":null}},{"node":{"id":"Question_12335-markdown","title":"I have psoriatic arthritis and was wondering if this would be the best product for chronic pain, inflammation, and sleep problems.","slug":"i-have-psoriatic-arthritis-and-was-wondering-if-this-would-be-the-best-product-for-chronic-pain-inflammation-and-sleep-problems","content":"\"@\"\n_____________________\nPsoriasis  is an autoimmune skin condition which leads to an overproduction of  skin cells called keratinocytes. The immune system mistakes components  of the body's own skin as pathogens, such as a virus or harmful  bacteria, that need to be removed from the body. This autoimmune  reaction leads to inflammation and an overproduction of skin cells,  resulting in scaling, itch and pain. Between 18% and 42%of people  with psoriasis develop psoriatic  arthritis (PA).\n\nThe endocannabinoid system (ECS) is the body's own  naturally occurring network of receptors and cannabinoids that is  involved in several bodily functions - immunoregulation being one of the  most important and extensively studied. Several  studies have shown that the CBD downregulates an overactive and self-attacking immune  reaction. \n https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044336/\n\nThe ECS is largely devoted to maintaining homeostasis (the  tendency of organisms to auto-regulate and maintain their internal  environment at  equilibrium). Deficiency or malfunction of the ECS has  become a focus for researchers seeking treatment options for several  maladies, including psoriasis and PA. In fact, the scientific community has   recently termed the ECS malfunction: Clinical Endocannabanoid  Decifiency, or CECD. Restoring balance to the ECS with phytocannabinoids, such as CBD and THC, is the crux of medicinal cannabis treatment.\n\ndrkim\n_____________________\nIn fact, the phytocannabinoids THC, CBD,  CBN and CBG have all been found  to inhibit keratinocyte proliferation in hyper-proliferating  keratinocyte cell lines, such as those found in psoriasis and PA.  Among the four  phytocannabinoids, CBD showed the most anti-proliferative potency, and required the lowest plasma concentration to inhibit keratinocye  overproliferation.\nhttps://www.google.com/search?client=firefox-b-1-ab&q=Wilkinson%2C+J.D.%2C+and+Williamson%2C+E.M.+%282007%2C+February%29.+Cannabinoids+inhibit+human+keratinocyte+proliferation+through+a+non-CB1%2FCB2+mechanism+and+have+a+potential+therapeutic+value+in+the+treatment+of+psoriasis.+Journal+of+Dermatological+Science%2C+45%282%29%2C+87-92.\n\nFurther, studies have showed that both endocannabinoids and  phytocannabinoids can directly treat the symptoms of psoriasis and psoriatic arthritis, such as  pain and itch.\nhttp://www.jaad.org/article/S0190-9622(17)30308-0/fulltext\nhttps://jamanetwork.com/journals/jama/fullarticle/233825\n\nAnd  finally, CBD can treat the the lost sleep, anxiety and depression  most psoriasis patients experience.  Beyond helping the patient better cope with the emotional toll psoriasis can cause, improving sleep and  lowering depression and anxiety can also reduce the frequency of  psoriasis flare-ups.\n\n\n\ndrkim\n_____________________\nThat product is an excellent choice: Rather than simply isolating CBD, Elixinol follows a  \"whole-plant philosophy\" which increases the oil's medicinal properties  by preserving accessory cannabinoids and terpenes—which all work  together in synergy to provide the \"entourage effect.\"  Furthermore,  rather than chemical solvents, Elixinol uses CO2 to extract CBD,  accessory cannabinoids and terpenes—which results in a more potent, pure  and safe CBD oil. \n\nFurther still, this product is very easily dosed, as the bottle specifies the miligrams of CBD per mililiter, drop or dropper-full.  Most CBD products are very poorly labeled, which leads to confusion and guessing.\n\nI hope this helps!\n\ndrkim","image":null}},{"node":{"id":"Question_11922-markdown","title":"My dad needs help with inflammation, what product is best and how much and how often?","slug":"my-dad-needs-help-with-inflammation-what-product-is-best-and-how-much-and-how-often","content":"\n_____________________\nIf you are looking for products that would reduce inflammation, my recommendation would be to look for products that are high in CBD. If you are in a state where cannabis is legal, either medically or recreationally, you would want to look for topicals, edibles, gel capsules, sublinguals, vape cartridges, and other cannabis derived products that are high in CBD. \n\nIf you are in a state where cannabis sales are prohibited and consumption is illegal, you would want to look for hemp derived CBD products, as hemp is not regulated the same way as cannabis, making it legal is most states throughout the US. Hemp-derived CBD contains a small percentage of the medicinal factors that cannabis derived CBD contains that can help with inflammation and anxiety, in addition to an array of other nutritional benefits like Omega-3 fatty acids, Vitamin E, etc. \n\nHow often you use these products would be entirely up to you, as we cannot make a recommendation for dosage. Although my advice would be to use the products when you feel your pain starting to flare up, or notice that you are experiencing more inflammation than normal. I would also recommend that you use the products at the first sight of pain or inflammation, as it would be more effective rather than trying to treat it when it is at an increased level. \n\nnsavelli\n_____________________\nHello,\nInflammation is a biological response of body tissues to harmful stimuli, such as infection or physical injury; it is a protective response involving immune cells, blood vessels, and molecular mediators.\n\nA paper published by the University of South Carolina, School of Medicine, stated that \"the fact that both Cannabinoid-1 and Cannabinoid-2 receptors have been found on immune cells suggests that cannabinoids play an important role in the regulation of the immune system.\" They found that when THC was administered, immune cell activity was reduced -- which essentially means that inflammation was reduced.  \nhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828614/\n\nAnd while cannabis research has historically focused on THC, synthetic cannabinoids, or our own naturally occurring cannabinoids (endocannabinoids), there is an evergrowing body of research regarding the anti-inflammatory effects of CBD. In a study with exciting implications, researchers concluded that, similar to THC, \"CBD, through its combined immunosuppressive and anti-inflammatory actions, has a potent anti-arthritic effect\" which may even block the progression of arthritis.\nhttps://www.ncbi.nlm.nih.gov/pubmed/10920191\n\n\n\ndrkim\n_____________________\nWhile there is no best cbd product, there is probably a ratio  of CBD:THC to better suit your own specific goals. Products with higher  concentrations of CBD vs THC, such as 20CBD:1THC, will lessen, or even  eliminate psychoactive effects, while still providing relief for most.  However, products with similar levels  of CBD and THC -- 1:1 has been the concentration most studied --  are more effective in many instances. So, for most people, it takes some trial and error before finding a compromise that works best, while also avoiding unwanted side effects. Dosages will vary  according to the patient's goals, pain level, cannbis-tolerance, current  medications, the CBD to THC ratio and other factors. Accordingly, I  recommend that you consult with a qualified physician. \n\n\ndrkim\n_____________________\nWhile there is no best cbd product, there is probably a ratio  of  CBD:THC to better suit your own specific goals. Products with higher   concentrations of CBD vs THC, such as 20CBD:1THC, will lessen, or even   eliminate psychoactive effects, while still providing relief for most.   However, products with similar levels  of CBD and THC -- 1:1 has been  the concentration most studied --  are more effective in many instances.  So, for most people, it takes some trial and error before finding a compromise that provides pain relief, while also avoiding unwanted side effects.  Dosages will vary  according to the patient's goals, pain level,  cannbis-tolerance, current  medications, the CBD to THC ratio and other  factors. \n\ndrkim\n_____________________\nWhile there is no best CBD product, there is probably a ratio of CBD:THC to better suit your own specific goals. Products with higher concentrations of CBD vs THC, such as 20CBD:1THC, will lessen, or even eliminate psychoactive effects, while still providing relief for most.  However, products with similar levels  of CBD and THC -- 1:1 has been the concentration most studied --  are more effective in many instances. So, for most people, it takes some trial and error before finding a comprimise that provides noticeable relief, while also avoiding any unwanted side effects. Dosages will vary  according to the patient's goals, pain level, cannabis-tolerance, current medications, the CBD to THC ratio and other factors. \nHere are a few products, offered in varying ratios of CBD:THC, which should help reduce inflammation:\n1.  https://www.cbd.org/products/cbd-sublingual-spray  \n2. http://dosist.com/pen-relief/\n3. https://www.cbd.org/products/cbd-chocolate \n4. https://shop.lordjones.com/collections/products/products/lord-jones-sigur-berry-high-cbd-gumdrops\n5. http://sensiproducts.com/product/sensi-chew-insomnia-plus-pure-cbd-melatonin/  \n6. http://kivaconfections.com/products/bars/ginger\n\ndrkim","image":null}},{"node":{"id":"Question_11909-markdown","title":"I have a lot of inflammation, can CBD help with fibromyalgia?","slug":"i-have-a-lot-of-inflammation-can-cbd-help-with-fibromyalgia","content":"\"My joints hurt a lot and my doctor says I may have fibromyalgia. Is there a difference between hemp CBD or CBD with THC from marijuana? \"\n_____________________\nYes CBD can be extremely beneficial for people suffering from fibromyalgia. The chemical compound in CBD helps reduce inflammation, which would alleviate your muscle pain. There are several differences between CBD oil and hemp derived oil. CBD oil is extracted from the actual cannabis plant, whereas hemp derived oil is extracted from the seeds of the hemp plant. The seeds of a hemp plant contain very low levels of CBD when compared to a cannabis plant, which can have high levels of CBD. \nHemp derived oil is used mainly for health benefits, while CBD oil is used medicinally. Hemp seeds are high in Omega-3 fatty acids, Vitamin E, and other beneficial aspects. \n\nnsavelli\n_____________________\nMr. Savelli has some very good ideas concerning CBD.  Every fibromyalgia pt is different.  In my experience,  I usually recommend pt's try products that have both CBD & THC (especially if pt's have sleep issues as well).  Mr. Savelli also mentioned omega-3's in hemp seed as well which is also a good suggestion;  omega-3's from fish oil, hemp, or even flaxseed are all good choices.  I would add that fibro treatment is tricky and needs to be multidisciplinary.  I've had the best success when also including for the pt:  1) a daily mild exercse & stretch regimen  &  2) cognitive behavioural psychotherapy (to retrain your brain to handle pain).  I hope all these tips prove useful!\n\n\ndrpark","image":null}},{"node":{"id":"Question_11788-markdown","title":"IBD and CBD","slug":"ibd-and-cbd","content":"\"Hello my 10year old daughter has IBD-UC and we want to avoid pharmaceuticals.  would love to hear from others about their experience with CBD products to decrease inflammation from autoimmune diseases, especially IBD.  thank you\"\n_____________________\nHello,\nActivating cannabinoid receptors has been demonstrated to inhibit gastrointestinal fluid secretion and inflammation in animal models. Several studies indicate that cannabinoids in marijuana bind with cannabinoid receptors in the digestive tract, especially the small and large intestine.\n\nFurthermore, both CBD and THC have been shown to reduce the inflammatory response in patients with autoimmune diseases, such as multiple sclerosis, lupus and celiac disease; both CBD and THC have  also been shown to help alleviate pain.  However, it is mainly THC, rather than CBD, that helps alleviate nausea and stimulate the appetite.\n\n\"CBD may interact at extra-cannabinoid system receptor sites, such as  peroxisome proliferator-activated receptor-gamma. This strategic  interaction makes CBD as a potential candidate for the development of a  new class of anti-IBD drugs.\"\nhttps://www.ncbi.nlm.nih.gov/pubmed/22815234\n\n\"CBD targets enteric reactive gliosis, counteracts the inflammatory  environment ... in human colonic cultures derived from UC patients. These actions lead to a reduction of intestinal damage. Our results therefore  indicate that CBD indeed unravels a new therapeutic strategy to treat  inflammatory bowel diseases.\"\nhttp://journals.plos.org/plosone/article?id=10.1371/journal.pone.0028159\n\ndrkim\n_____________________\nHello! I agree with Dr. Kim's very nice answer. Since your daughter is 10, I would recommend she try CBD rich products since they are less psychoactive. CBD is a powerful antiinflammatory compound, which often helps with inflammatory bowel diseases. A tiny bit of THC helps the CBD to work more effectively. I might suggest you try a ratio of at least 12:1 CBD to THC in a sublingual tincture. Start with a couple drops and observe the effects. You can increase the dose if necessary over time. Hope this helps. Best of luck.\n\ndrjacquelynlew","image":null}},{"node":{"id":"Question_11787-markdown","title":"What is the best cbd oil product for aleviating pain and inflammation from RA?","slug":"what-is-the-best-cbd-oil-product-for-aleviating-pain-and-inflammation-from-ra","content":"\n_____________________\nWhile there is no best cbd oil product, there is probably a best ratio of CBD:THC to suit your goals. Products with higher concentrations of CBD vs THC, such as 20CBD:1THC will cause less, or even eliminate, psychoactive effects. However, products with similar levels of CBD and THC have been shown to alleviate pain most. So, for most people, it takes some trial and error before they find an ideal compromise. \nHere are a few recommended products for arthritic pain:\nhttps://www.cbd.org/products/cbd-chocolate \nhttps://www.cbd.org/products/cbd-sublingual-spray\nhttp://dosist.com/pen-relief/ , which is a 2CBD:1THC vaporizer pen. I recommend vaporizer pens by dosist because, unlike conventional vaporizer pens, they buzz after a single metered dose - which allows for the most precise dosing among all inhalation methods. For most of my patients, I recommend one to two puffs every one to three hours as needed.\nhttps://drkerklaan.com/products/pain-cream\n1:1 topical cream\n\n\n\ndrkim","image":null}},{"node":{"id":"Question_9194-markdown","title":"How long does cannabis reduce inflammation?","slug":"how-long-does-cannabis-reduce-inflammation","content":"\n_____________________\nBUY CANNABIS  We have top quality medical cannabis buds, oil extract,wax, hash and edibles available at affordable prices. You can text me at 3033512578 if you need some medical marijuana. We ship discreetly worldwide ,100% delivery guarantee and you can visit our site legalonlineweedsuppliers.com Contact me for more details. Thanks\n\nJonathanzeus\n_____________________\nHello, we've got an article on how cannabis, specifically CBD, can help reduce inflammation. As well, a terpene called beta-caryophyllene appears to help control inflammation. Meanwhile, we have a few experts in the community who've answered similar questions. Tatiana, a nurse practitioner, suggests daily consumption of cannabis capsules: https://www.hellomd.com/answers/59950db3a38c620eed3e778b/how-much-cbd-should-i-take-daily-for-pain-and-inflammation. As do others--in this case, a CBD tincture: https://www.hellomd.com/answers/584659849df65d000801dae5/what-is-a-good-tincture-for-inflammation-and-back-pain. I've heard anecdotal reports that daily dosing with high CBD is helpful in relieving inflammation (& pain), but that there is a cumulative effect--meaning, the CBD builds up in your body and becomes increasingly effective over time (with 2-3 months of consistent use). It's something I'm trying, but am only in the beginning stages. Dosing is unique to the individual, so trial & error is par for the course.\n\nlyp","image":null}},{"node":{"id":"Question_7719-markdown","title":"How much CBD should I take daily for pain and inflammation?","slug":"how-much-cbd-should-i-take-daily-for-pain-and-inflammation","content":"\"I have pain and inflammation in my hands stemming from neck injury. I have some 18:1 CBD:THC capsules, how often and how many should I take?\"\n_____________________\nFor chronic pain, I normally suggest starting at a 1:1 CBD/THC containing 5-10mg, titrating upwards in mgs as needed. It is difficult to give you an accurate dose recommendation without knowing the milligrams of the CBD/THC contained in each capsule of the medication you have in hand. But, assuming each capsule contains around 9.65mg CBD & 0.51mg THC, I would recommend one or two capsules a day depending on the severity of the pain .\n\ntatiananp","image":null}},{"node":{"id":"Question_10278-markdown","title":"What cannabis medication might best reduce inflammation caused by compression of spinal nerves by vetebrae?  ","slug":"what-cannabis-medication-might-best-reduce-inflammation-caused-by-compression-of-spinal-nerves-by-vetebrae","content":"\n_____________________\nI would suggest a High CBD strain that has some THC in it. CBD has been shown to be very helpful with pain and inflammation. \nHere is a link to Projectcbd.org...they list a number of articles and PubMed studies done with cannabis and inflammation...worth a read!\n\nPiantaTinta","image":null}},{"node":{"id":"Question_10066-markdown","title":"Which is better for inflammation and pain from ulcerative colitis, hemp oil or cannabis oil? ","slug":"which-is-better-for-inflammation-and-pain-from-ulcerative-colitis-hemp-oil-or-cannabis-oil","content":"\n_____________________\nHemp and cannabis are very closely related plants but the terms typically refer to very different kinds of medicine.  If you are looking at hemp oil the most important piece of information is to look for CBD content (if any).  For instance, hemp oil without cannabinoids might be used as a dietary supplement, but hemp oil made from CBD-producing plants can be used for medicinal purposes.  Cannabis oil generally refers to oil extracted from cannabis flower, and will contain various amounts and ratios of cannabinoids like THC and CBD.  That oil can then be put into various types of medical marijuana products like vaporization oil, topical creams, edibles, etc.  For ulcerative colitis, most people find that using a combination of THC and CBD helps relieve symptoms of pain and inflammation.\n\ndrbultman","image":null}},{"node":{"id":"Question_9766-markdown","title":"looking to buy CBD patch for inflammation. where can i buy them?","slug":"looking-to-buy-cbd-patch-for-inflammation-where-can-i-buy-them","content":"\n_____________________\nHi there, \n\nThis company makes patches: http://www.marysmedicinals.com/\n\nI would contact your nearest dispensary and or delivery service and see if they carry this product! \n\nThank you!\n\nnurit\n_____________________\nI have psoriatric arithridus. Scoliosis and depression. Also PTSD. I can't stand my feet and hands swell up and hurt bad. I get no relief. Please help. Would like to try a patch. I just lost my husband to Prostate Canser.  He had to wear an opioid patch. Can you help me.\n\nruthless","image":null}},{"node":{"id":"Question_9615-markdown","title":"I need something for post surgical pain relief.  I'm allergic to opiates and anti-inflammatory drugs.  ","slug":"i-need-something-for-post-surgical-pain-relief-im-allergic-to-opiates-and-anti-inflammatory-drugs","content":"\"Hip surgery to include bone screws is pending.  I cannot be prescribed any meds for pain or inflammation.  I have Ehlers-Danlos Syndrome (EDS). \"\n_____________________\nI would use a high CBD tincture like 18:1 Care by Design and anything with high CBD for pain control.\n\njrec","image":null}}]}},"pageContext":{"limit":12,"skip":0,"numPages":3,"currentPage":1,"id":5385,"name":"Inflammation","slug":"inflammation","country":"US"}},"staticQueryHashes":["3949754563","4179947113","4202924991"]}