{"componentChunkName":"component---common-build-questions-template-js","path":"/questions-and-answers/cannabis-for-itchy-skin","result":{"data":{"question":{"title":"Cannabis for itchy skin ","slug":"cannabis-for-itchy-skin","createdAt":"October 8, 2020","image":null,"tags":[{"id":5052,"name":"Cannabis","slug":"cannabis"}],"childMarkdownRemark":{"excerpt":"Hi there!\nThere  are several studies that suggest that cannabis is may be an effective  treatment for several…","html":"<hr>\n<p>Hi there!\nThere  are several studies that suggest that cannabis is may be an effective  treatment for several dermatologic conditions, including prurits (itch).<br>\n<a href=\"https://www.ncbi.nlm.nih.gov/pubmed/30142706\">https://www.ncbi.nlm.nih.gov/pubmed/30142706</a></p>\n<p>In a 2003 clinical study, researchers concluded that in peripheral administration of a cannabinoid receptor agonist attenuates histamine-induced itch.\" Researchers used the synthetic CB1 (cannabinoid receptor 1) agonist HU21 -- THC is a plant-derived CB1 agonist. Interestingly,  HU210 did not reduce histamine levels. Rather, when the CB1 receptor  was activated, it prevented the signaling of the nerve itself after  histamine had already bound its receptor.\n<a href=\"https://link.springer.com/article/10.1007/s00011-003-1162-z\">https://link.springer.com/article/10.1007/s00011-003-1162-z</a></p>\n<p>In  a 2002 clinical study, researchers found that three weeks of topical  application of a cream containing our own cannabinoids  (endocannabinoids) dramatically reduced itch from uremic pruritis  (caused by kidney failure).\n<a href=\"https://www.ncbi.nlm.nih.gov/pubmed/16324422?dopt=Abstract\">https://www.ncbi.nlm.nih.gov/pubmed/16324422?dopt=Abstract</a></p>\n<p>drkim</p>\n<hr>\n<p>In a 2002 clinical study evaluating the efficacy of THC in treating  patients with severe itch caused by cholestatic liver disease,  researchers found that nightly administration of 5mg of THC resulted in  reduced itch and better sleep.\n<a href=\"https://www.ncbi.nlm.nih.gov/pubmed/12190187\">https://www.ncbi.nlm.nih.gov/pubmed/12190187</a></p>\n<p>I generally recommend topical creams containing both THC and CBD, such as\n<a href=\"https://www.hellomd.com/products/5b6e09bd96120c00012c6935/13-releaf-balm\">https://www.hellomd.com/products/5b6e09bd96120c00012c6935/13-releaf-balm</a>\n<a href=\"https://www.hellomd.com/products/5b6e0e4a96120c00012c6946/31-releaf-balm\">https://www.hellomd.com/products/5b6e0e4a96120c00012c6946/31-releaf-balm</a>\nIf  the itch were generalized or covering large areas, I generally would  recommend a tincture, oil or edible with a moderate concentration of THC  -- ratio between 3:1 and 8:1, such as\n<a href=\"https://www.hellomd.com/products/58ed554dc064b41d82fad295/41-sublingual-drops\">https://www.hellomd.com/products/58ed554dc064b41d82fad295/41-sublingual-drops</a>\n<a href=\"https://www.hellomd.com/products/5ab445285ff2ea000b4e974d/41-soft-gel-capsules\">https://www.hellomd.com/products/5ab445285ff2ea000b4e974d/41-soft-gel-capsules</a></p>\n<p>I hope this helps!</p>\n<p>drkim</p>","timeToRead":2}},"defaultImage":{"childImageSharp":{"fluid":{"base64":"data:image/jpeg;base64,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","aspectRatio":1.5,"src":"/static/1e164eb4ee29aff63b63675577d389d3/a07a5/question-default-image.jpg","srcSet":"/static/1e164eb4ee29aff63b63675577d389d3/decd9/question-default-image.jpg 150w,\n/static/1e164eb4ee29aff63b63675577d389d3/15aed/question-default-image.jpg 300w,\n/static/1e164eb4ee29aff63b63675577d389d3/a07a5/question-default-image.jpg 600w,\n/static/1e164eb4ee29aff63b63675577d389d3/701ee/question-default-image.jpg 800w","srcWebp":"/static/1e164eb4ee29aff63b63675577d389d3/483a3/question-default-image.webp","srcSetWebp":"/static/1e164eb4ee29aff63b63675577d389d3/e8bcc/question-default-image.webp 150w,\n/static/1e164eb4ee29aff63b63675577d389d3/4fec1/question-default-image.webp 300w,\n/static/1e164eb4ee29aff63b63675577d389d3/483a3/question-default-image.webp 600w,\n/static/1e164eb4ee29aff63b63675577d389d3/2ad7f/question-default-image.webp 800w","sizes":"(max-width: 600px) 100vw, 600px"}}}},"pageContext":{"id":12361,"slug":"cannabis-for-itchy-skin","country":"US"}},"staticQueryHashes":["3949754563","4179947113","4202924991"]}