{"componentChunkName":"component---common-build-questions-template-js","path":"/questions-and-answers/does-cbd-or-thc-lower-platelet-and-white-blood-cell-count","result":{"data":{"question":{"title":"Does CBD or THC lower platelet and white blood cell count?","slug":"does-cbd-or-thc-lower-platelet-and-white-blood-cell-count","createdAt":"October 8, 2020","image":null,"tags":[],"childMarkdownRemark":{"excerpt":"\"In the case of a Glioblastoma brain tumor that was removed 99%. Supplementing treatment with CBD and some THC at night…","html":"

\"In the case of a Glioblastoma brain tumor that was removed 99%. Supplementing treatment with CBD and some THC at night. Platelet count is low and not responding to injections. Liver enzyme numbers are also going the wrong way. \"

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Hello,

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I don't believe cannabis has contributed to the low platelet count. In fact, in a 2014 study, researchers concluded that the endocannabinoid 2-AG stimulated baby blood cells to become platelets (megakaryocytic differentiation).  2-AG, like THC (a phytocannabinoid), binds the cannabinoid-1 (CB1) and cannabinoid-2 receptors (CB2), leading to different physiological reactions, such as lowering inflammation and stimulating platelet formation. However, this study used supraphysiological doses and most likely would not translate to real-world doses of cannabis.

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https://www.ncbi.nlm.nih.gov/pubmed/25427281\nAdditionally, there are several studies which suggest than cannabis increases platelet function, which is why researchers are investigating cannabis' potential as a treatment for coagulation disorders, such  Hemophilia A. However, these studies also involved supraphysiological doses.

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190025/#bib9I\nI hope this was helpful.

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drkim

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