{"componentChunkName":"component---common-build-tags-template-js","path":"/tag/psychedelics/","result":{"data":{"allArticle":{"edges":[{"node":{"id":"Article_3937-markdown","title":"Microdosing Psychedelics: LSD, Psilocybin & Cannabis","slug":"microdosing-psychedelics-lsd-psilocybin-and-cannabis","content":"Not too long ago, LSD, \"magic mushrooms,\" and other kinds of psychedelic substances belonged to the domain of the drug subculture, where people used these powerful substances to alter consciousness in radical ways.   \n\nIn recent years, people have begun to experiment with [microdosing or regularly taking psychedelics such as LSD, psilocybin or cannabis in very small amounts](https://thethirdwave.co/microdosing/). Anecdotal reports indicate that many consumers find that they have considerable benefits for mental and physical health. \n\nHere's what you need to know about microdosing psychedelics safely to enhance mental clarity, creativity, and more.\n\n### Psychedelics: From the Underground to the Mainstream\n\nIt isn't clear when people first began to use psychedelic plants and other substances to change their perceptions, but some evidence indicates that the practice is ancient. In modern times, psychedelic substances leaped into public awareness in the drug-fueled days of the 1960s, and they've remained a popular recreational option ever since.\n\n![Untitled15-min.png](https://hellomd-cms.s3.us-west-2.amazonaws.com/Untitled15_min_f950fb257f.png)\n\nNow, though, these substances are moving out of the psychedelic subculture, as [new studies reveal ](https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0211023) that consuming them at very low, or \"sub-perceptual\" amounts produce positive outcomes without psychoactive effects. \n\nThe modern microdosing trend has its roots in James Fadiman's 2011 book The Psychedelic Explorer'sExplorer's Guide: Safe, Therapeutic and Sacred Journeys. In it, Fadiman explored the concept of microdosing for healing and spiritual benefits.\n\nNow, researchers across the globe have begun to take a closer look at the effects of tiny doses of these mind-altering substances. And they've discovered that [microdosing at levels below psychoactivity](https://www.hellomd.com/articles/microdosing-the-big-new-trend) can affect the Brain in many surprising and beneficial ways.\n\n### How Does Microdosing Work?\n\nAt high or \"standard\" doses, psychedelics alter consciousness in a multitude of ways. \n\n![Tab of LSD cut up into a microdose](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_04_07_at_1_03_12_PM_81f64861fd.png)\n\nFrom the euphoric high of THC-powered cannabis to the hallucinations and dissolving sense of self in LSD or mushroom trips, these substances can change the way people perceive the world and themselves. But that kind of experience can also interfere with daily living.\n\nMicrodosing psychedelics triggers activity in [key areas of the brain](https://www.hellomd.com/articles/exploring-mind-bending-psychedelics-psilocybin-and-lsd) but at levels well below the amounts that typically trigger psychoactivity. The result boosts well-being for many users, including relief from anxiety and depression, enhanced creativity and focus, and improved relationships. Some users also say that microdosing can reduce migraine and relieve pain.\n\nBut microdosing also has its downsides. Not everyone can tolerate psychedelics, even in small doses. Microdosing these substances can cause visual disturbances, insomnia, digestive problems, and problems concentrating. Other side effects can include numbness and tingling in fingers and toes, anxiety, or depression.\n\n### Psychedelics Activate Pathways in the Brain\n\nLSD, cannabis, and psilocybin top the list of psychedelic substances used for microdosing, thanks to their ability to mimic substances naturally produced by the body.\n\n![Psychedelics alter pathways in the brain](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_04_07_at_1_04_06_PM_c2481d1139.png)\n\nLSD (lysergic acid diethylamide) is a long-lasting psychedelic that produces vivid hallucinations and other altered perceptions. It [binds to cell receptors in the brain](https://www.nih.gov/news-events/nih-research-matters/protein-structure-reveals-how-lsd-affects-brain#:~:text=Lysergic%20acid%20diethylamide%2C%20or%20LSD,been%20cleared%20from%20the%20bloodstream) that respond to serotonin, a neurotransmitter that helps cells communicate. Serotonin has also been called the \"feel-good chemical\" for its ability to reduce anxiety and boost mood. LSD can also activate receptors related to sensory processing and cognition.\n\nPsilocybin is a chemical compound present in certain types of mushrooms. Like LSD, [psilocybin affects serotonin receptors in the brain](https://www.psychologytoday.com/us/blog/the-athletes-way/201811/is-your-brain-microdoses-psilocybin). But along with boosting the flow of serotonin, \n\"magic mushrooms\" also appear to destabilize existing neural networks and even create new ones. That accounts for expanding consciousness and new ways of thinking that people experience when they use psilocybin.\n\n![Cannabis can be a great way to microdose](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_04_07_at_1_05_17_PM_153ae1727d.png)\n\nCannabis contains THC (delta 9 tetrahydrocannabinol), which causes its famous \"high.\" THC [mimics the activity of anandamide](https://nida.nih.gov/publications/research-reports/marijuana/how-does-marijuana-produce-its-effects), a cannabinoid chemical similar to serotonin that's naturally produced by the body. THC binds to the same cannabinoid receptors in the brain, triggering activity on various pathways, including those related to mood, pleasure/reward, and cognition. \n\nResearchers believe that when they're taken in tiny sub-perceptual doses, these psychedelics stimulate activity in the brain's pathways for cognition, mood, and pleasure, opening new avenues for thinking and perceiving without causing impairment. Microdosing holds promise for treating diseases like Parkinson's and Alzheimers and relieving the symptoms of PTSD and other mental health conditions.\n\n### How to Microdose Safely\n\nAlthough there's increasing evidence for the benefits of microdosing, it's important to do so safely. \n\nHere are a few [things to keep in mind]( https://microdosinginstitute.com/how-to/microdosing-protocols/).\n\n#### Be aware of legal issues\nCannabis is legal in many areas, so it's relatively easy to find cannabis products in varying strengths and forms. But LSD and psilocybin remain illegal in the US, with stiff penalties for possession of these and other psychedelic substances. In some counties and cities, such as Oakland, CA or Denver, CO, within the US, psychedelics are decriminalized, which means it is unlikely you will be prosecuted with small amounts within your personal possession.\n\n#### Seek out quality products from reputable sources\n\nChoose products produced without harmful additives or processing, and look for clear statements about a product's contents, origin and potency whenever possible.\n\n![Psilocybin ](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_04_07_at_1_08_04_PM_d35331777f.png)\n\n\n#### Keep in mind that psychedelics can vary considerably in form and content\nCannabis can be smoked, vaped, eaten, or consumed as a tincture, and these methods are not equally suitable for microdosing. Psilocybin mushrooms can contain varying amounts of psilocybin, and LSD may not be equally distributed on a tab of paper.\n\n#### Start with a low dose\nIt can take some time to find the best dose for your needs, so start with a low dose and adjust accordingly as you observe your reactions.\n\n#### Dose consistently\nTake steps to ensure that each dose contains the same amount of your chosen psychedelic. For LSD, where the chemical may not be evenly distributed, a method like volumetric dilution can keep doses consistent. For cannabis, low-dose edibles such as chocolates or capsules can make it easy to get the right dose every time. For psilocybin, use a standard measure for placing ground or powdered mushrooms into capsules.\n\n![Vaping cannabis](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_04_07_at_1_10_15_PM_0b7de5b0a1.png)\n\n#### Maintain a dosing protocol\n\nMicrodosing experts recommend starting with the lowest possible dose on a regular schedule, typically one out of three days. Keep a journal or log of your experiences and the doses you take to track your progress and determine whether you need to change the dose or frequency. Consider taking a break from your protocol every few weeks to avoid building up a tolerance to the substance.\n\n \n### Get a Medical Marijuana Card Online\nIt'sIt's easy to get your medical marijuana document with the online [Telehealth service HelloMD](https://hellomd.com/get-started). Register, pay, and receive an online medical consultation with a licensed practitioner and purchase medical cannabis today. You don't pay unless you're approved!\n\n\n\n\n\n","image":{"childImageSharp":{"fluid":{"base64":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABQAAAANCAIAAAAmMtkJAAAACXBIWXMAAA7EAAAOxAGVKw4bAAADEElEQVQozyWSe2gcdRDHZ/eSuxw9S17aVGkwBEottqBSMFIQKyQaY0vaWmvpH5UmlRCxgogQohTRiGjaaCRaWyw2fSVpLLVNSrW01jYkaUPeub3H3u7eI3e7l33c7d3u77e3e4l7CMMw/3zmO/OdAYOHnECYScIUC2FJYImkJRGWTORlwhKJfCFIa8WuwRTA5AkzTpgxyEUBjGXAAmHYcNLu4rTiLhsrkAWgKG93EYvyMpjJYnPZZQpEQWnZkYsUGTassSXKz9+iH7qEi5/m+tvUP1qzfV+pV4/pv32mnuvMXm5Xz3Wol44bv3+Uub1HOt2lft+rnv/EHDxYgLMBT+zErXTnUPjELevyYfFBk/ThpPRjt3iyT+z5ie/5RfzubOrM51r/caXvG/7La3L7uND9q977RY5xQIZ6Qhx9W7mxVxpuzV05kh45oAy3aNcP4aH3s4MfoBv7MwNt6K9GY7Q5++e78vAxZfBodqAFD7yHw7YyDToHKAKGADjmQtRGgylF9FOYLcf0BiPsMbhyHKpEgSpEV1gJ0rINThScQqwNB0GjSY0GHHZgzokDFZgutbPuq0DUJhwqN0IOHChD3ipEVRkMaURIHC5GDKkzhZ1BY1w4sdmIwP83WE06VmXnmlppCZBfKV7Tdq0p61cldz5JrsmbcjES2ZMyoIcIyPgh5XfP3qvTuHUJ7z4kNKRiDXyw6fHtej3sVpiaRxOn4oF3EtRrerTWO92BOPt+z+tsiRYESFNEahECD2ukwHPs3JvzD96i7j4z8/eLUxdAje0MjDWfboeFkS3xqRr+Edzpr8tQnvs39yWmPSgEkFpypBdB5nZL1LPBye0jX0OSalye3YE4h0jXp5nd4iQIM9Vq7GXMQnj2DdXr+ufCluiYU7eV5XnbsHVLD19fmYbEwrbkdFnU9zE/VaJFq0XfVpk7ZL9hhvbwvpdQuESgdij0C/77r6TmIL1EgBZ0e8d3/nt+Q2oJohNPpvyl7MJh1QsqV6v4n47MvqqytRrrjCzWqX6IB5sW7zbyE5DxgjIP/wE9hO+5U38lHQAAAABJRU5ErkJggg==","aspectRatio":1.5037593984962405,"src":"/static/dfc7664135788b59dc825a013becddb7/ee604/7e9f725af7bbb30cb17b281995a7b6bd.png","srcSet":"/static/dfc7664135788b59dc825a013becddb7/69585/7e9f725af7bbb30cb17b281995a7b6bd.png 200w,\n/static/dfc7664135788b59dc825a013becddb7/497c6/7e9f725af7bbb30cb17b281995a7b6bd.png 400w,\n/static/dfc7664135788b59dc825a013becddb7/ee604/7e9f725af7bbb30cb17b281995a7b6bd.png 800w,\n/static/dfc7664135788b59dc825a013becddb7/f3583/7e9f725af7bbb30cb17b281995a7b6bd.png 1200w","srcWebp":"/static/dfc7664135788b59dc825a013becddb7/58556/7e9f725af7bbb30cb17b281995a7b6bd.webp","srcSetWebp":"/static/dfc7664135788b59dc825a013becddb7/61e93/7e9f725af7bbb30cb17b281995a7b6bd.webp 200w,\n/static/dfc7664135788b59dc825a013becddb7/1f5c5/7e9f725af7bbb30cb17b281995a7b6bd.webp 400w,\n/static/dfc7664135788b59dc825a013becddb7/58556/7e9f725af7bbb30cb17b281995a7b6bd.webp 800w,\n/static/dfc7664135788b59dc825a013becddb7/99238/7e9f725af7bbb30cb17b281995a7b6bd.webp 1200w","sizes":"(max-width: 800px) 100vw, 800px"}}}}},{"node":{"id":"Article_3936-markdown","title":"What Is Salvia: Psychedelics 101","slug":"what-is-salvia-psychedelics-101","content":"Salvia is one of the many hallucinogens consumed by psychedelic enthusiasts with a deep history of [ritualistic applications by the Mazatec Indians](https://tinyurl.com/5dfr8zjp). Indigenous tribes have consumed salvia for thousands of years for spiritual healing, and shamans would offer the tea brewed from the herb's leaves to people for therapeutic purposes. There are similarities between traditional and indigenous consumption of salvia and the use of San Pedro cacti which contains the alkaloid mescaline. \n\nRecently, salvia has seen a resurgence of interest in modern culture, not necessarily as a therapeutic treatment but more as a recreational drug.\n\n![Salvia is a plant similar to mint](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_04_05_at_3_49_44_PM_3e775636a4.png)\n\n### What Is Salvia?\n\nSalvia or salvia divinorum is a perennial herb indigenous to Oaxaca, Mexico, and belongs to the mint family (i.e., Lamiaceae). The herb goes by the street name of Sally-D, Magic Mint, Maria Pastora, and Diviner's Sage. Salvia leaves take on a green spade-shaped appearance that closely resembles mint leaves. \n\nWhen smoked or chewed, salvia produces a [strong hallucinogenic effect](https://tinyurl.com/yckjdne9) in roughly five to ten minutes and usually lasts for 30 minutes up to a few hours. Psychedelic practitioners who use salvia usually avoid rolling them into joints since the preparation may significantly reduce the potency of the dried herb.  \n\n![Salvia has a rapid onset](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_04_05_at_3_52_50_PM_eccb1dc612.png)\n\n### What Are the Effects of Salvia?\n\nSalvia plants contain a potent hallucinogenic compound called salvinorin A, which affects the natural human brain chemistry. Salvinorin A affects how neurons in the brain naturally communicate/signal and change the way they release neurotransmitters that drive thought processes. \n\n![Salvia creates hallucinogenic effects](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_04_05_at_3_47_48_PM_bb85f97c76.png)\n\nThe National Drug Intelligence Center (NDIC) recommends less than 500 grams for each salvia dose due to its potency. Salvinorin A produces neurological effects by attaching itself to a brain subcomponent called the kappa opioid receptors. Conventional recreational drugs like [MDMA](https://tinyurl.com/26bmuyk4) and opium target the mu-opioid receptors that result in addiction. \n\nIn comparison, salvinorin's link with the kappa opioid receptors might cause [depressive effects](https://tinyurl.com/2p9cpdxu) that deter addiction. As such, scientists have considered salvia in the medical advancements of [Alzheimer's treatment and coping with chronic pain](https://tinyurl.com/mux5atd4) since interaction with the kappa opioid receptors result in in in analgesic effects without causing addiction. \n\n![Untitled100.png](https://hellomd-cms.s3.us-west-2.amazonaws.com/Untitled100_ad4a10f68d.png)\n\n### What Are the Therapeutic Benefits of Salvia?\n\nThe Salvia plant provides various benefits, such as an [increased defense against cancer and viral infections](https://tinyurl.com/y9d6y99a). Salvia achieves the process by selectively shutting off malignant cell proliferation (i.e., replication) and inhibiting cancerous tumor growth. \n\n![Salvia can help headaches](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_04_05_at_3_53_50_PM_0b0f32e024.png)\n\nSalvia users have reported a wide range of potential health benefits, however, these require further research for conclusive results. The list of potential therapeutic effects includes the relief of:\n\n- [headache](https://tinyurl.com/yceu7c5c)\n- bloating\n- [rheumatism](https://tinyurl.com/yus5cn9t)\n- [diarrhea](https://tinyurl.com/5532s53b) \n\nIt is essential to note that US healthcare authorities currently do not approve of salvia for official medicinal uses, and there are risks associated with its use. \n\n![Untitled99.png](https://hellomd-cms.s3.us-west-2.amazonaws.com/Untitled99_255eef0a24.png)\n\n### Are There Any Risks Associated With Salvia?\n\nSimilar to most hallucinogenic products, there are health risks associated with salvia use, depending on factors such as an individual's health condition, preparation method, and the administered dosage. \n\n![Hallucinations are common on salvia](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_04_05_at_3_55_44_PM_24b3dcea69.png)\n\nThe most common side effects of salvia use include intense hallucinations, profuse sweating, mood disorders, loss of coordination, a sense of disconnect/desensitization from immediate surroundings, slurred speech, laughing fits, and jumbled senses (e.g., the ability to smell colors or taste sound). \n\nIn severe cases, consumers may lose touch with reality, resulting in reckless behavior. Due to salvia's generally rapid effects, consumers generally recover from its effects quickly. \n\n![Untitled101.png](https://hellomd-cms.s3.us-west-2.amazonaws.com/Untitled101_2538a05e3c.png)\n\n### Is Salvia Legal?\n\nSalvia remains legal under Federal law. However, many countries and states have created laws to regulate or outlaw its use. \nFor example, the state laws in Delaware, Florida, Hawaii, Illinois, Kansas, Kentucky, Minnesota, Mississippi, Missouri, Nebraska, North and South Dakota, Ohio, Oklahoma, and Virginia have banned salvia. \n\nSimilarly, many countries have made salvia consumption illegal, including Australia, Belgium, Croatia, Denmark, Germany, Italy, Japan, Latvia, Lithuania, Poland, Romania, South Korea, and Sweden.\n\nSince salvia remains unprohibited in some states, US psychedelic companies have sold the herb as an alternative to [LSD](https://tinyurl.com/2p8m2fpr) and mescaline. \n\n![Untitled96.png](https://hellomd-cms.s3.us-west-2.amazonaws.com/Untitled96_270c624e1a.png)\n\n### Where Can I Legally Seek Salvia Treatment?\n\nYou may find salvia-based therapy in states that have not outlawed the drug. While many states have created laws to restrict salvia use, you may still find the products legally available in Arizona, Idaho, Massachusetts, Nevada, New Hampshire, New Mexico, New York, Oregon, Rhode Island, South Carolina, and Washington. \n\nYou may also acquire salvia treatment in California and Maine with the age restriction of 18 years and 21 years in Maryland.  \nGet Your Medical Document & Purchase Medical Cannabis\nIt's easy to get your medical document with the online Telehealth service HelloMD. Register, pay, and receive an online medical consultation with a licensed practitioner and start purchasing medical cannabis today.\n\n### Get Your Medical Document & Purchase Medical Cannabis\n\nIt's easy to get your medical document with the online [Telehealth service HelloMD](https://www.hellomd.com/get-started/). Register, pay, and receive an online medical consultation with a licensed partitioner and purchase medical cannabis today.","image":{"childImageSharp":{"fluid":{"base64":"data:image/png;base64,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","aspectRatio":1.5037593984962405,"src":"/static/c2535026299e7f5a9cbc123f4322151d/ee604/7590070c7eef465cfd4fa9bdabb43cc6.png","srcSet":"/static/c2535026299e7f5a9cbc123f4322151d/69585/7590070c7eef465cfd4fa9bdabb43cc6.png 200w,\n/static/c2535026299e7f5a9cbc123f4322151d/497c6/7590070c7eef465cfd4fa9bdabb43cc6.png 400w,\n/static/c2535026299e7f5a9cbc123f4322151d/ee604/7590070c7eef465cfd4fa9bdabb43cc6.png 800w,\n/static/c2535026299e7f5a9cbc123f4322151d/f3583/7590070c7eef465cfd4fa9bdabb43cc6.png 1200w","srcWebp":"/static/c2535026299e7f5a9cbc123f4322151d/58556/7590070c7eef465cfd4fa9bdabb43cc6.webp","srcSetWebp":"/static/c2535026299e7f5a9cbc123f4322151d/61e93/7590070c7eef465cfd4fa9bdabb43cc6.webp 200w,\n/static/c2535026299e7f5a9cbc123f4322151d/1f5c5/7590070c7eef465cfd4fa9bdabb43cc6.webp 400w,\n/static/c2535026299e7f5a9cbc123f4322151d/58556/7590070c7eef465cfd4fa9bdabb43cc6.webp 800w,\n/static/c2535026299e7f5a9cbc123f4322151d/99238/7590070c7eef465cfd4fa9bdabb43cc6.webp 1200w","sizes":"(max-width: 800px) 100vw, 800px"}}}}},{"node":{"id":"Article_3929-markdown","title":"How to Make Magic Mushroom Chocolates","slug":"how-to-make-magic-mushroom-chocolates","content":"Cannabis legalization has swept the country and on its heels is the next wave - the decriminalization and legalization of psychedelics. Research into the therapeutic potential of psychedelic medicine has come to the fore through organizations such as [MAPS]( https://maps.org/), [The Imperial College of London]( https://www.imperial.ac.uk/psychedelic-research-centre/), and [Johns Hopkins University](https://hopkinspsychedelic.org/), to name a few. In the U.S., the FDA has granted breakthrough status to both [MDMA](https://www.hellomd.com/articles/what-is-mdma-psychedelics-101) and [Psilocybin]( https://www.hellomd.com/articles/what-is-psilocybin-psychedelics-101), aka magic mushrooms, for treatment-resistant depression as well as PTSD and both substances are tracking to be fully legal within clinical settings by 2024.\n\n![Magic mushrooms are becoming very popular](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_03_31_at_12_30_28_PM_458ec7ebd5.png)\n\n### Psychedelics go Mainstream\n\nAs people become more aware of the therapeutic application of psychedelics, there has also been a resurgence of recreational consumption. What was once counter-culture is now becoming mainstream culture. The [decriminalization movement]( https://en.wikipedia.org/wiki/Psilocybin_decriminalization_in_the_United_States#:~:text=In%20January%202020%2C%20Santa%20Cruz,of%20psilocybin%20is%20still%20illegal.) which advocates for personal possession of psychedelics to no longer be considered a crime, is also bringing psychedelics out of the closet.\n\nStates as well as individual cities such as [Seattle](https://www.marijuanamoment.net/seattle-becomes-largest-u-s-city-to-decriminalize-psychedelics/), [California]( https://www.nbcnews.com/news/us-news/california-moves-closer-decriminalizing-psychedelic-drugs-n1279509),[Oklahoma](https://www.marijuanamoment.net/oklahoma-house-passes-psilocybin-decriminalization-and-research-bill-sending-it-to-senate/), and [Detroit](https://www.pbs.org/newshour/politics/detroit-just-decriminalized-psychedelics-and-magic-mushrooms-heres-what-that-means) are in the process of passing legislation to decriminalize psychedelics. Decriminalization allows for a new opportunity and freedom for experimentation with psychedelics, including the ever-popular magic mushrooms. \n\n![Magic mushroom chocolate is easy to make](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_03_31_at_12_32_38_PM_72149040af.png)\n\nIn this article we give an overview of psilocybin and give you the how-to steps to make your own magic mushroom chocolates.\n\n### What are Magic Mushroom Edibles?\n\n[Psilocybin](https://www.hellomd.com/articles/what-is-psilocybin-psychedelics-101) is a chemical compound found within specific types of mushrooms. When you consume psilocybin, it turns into psilocin, which has psychoactive properties that cause a psychedelic experience. \n\nThe most common ways to consume magic mushrooms are by mixing them into foods, brewing them in teas, or eating dried mushrooms raw. \n\nIn a similar fashion to [cannabis edibles](https://www.hellomd.com/articles/essentials-about-edibles-that-you-need-to-know), psilocybin edibles are made from dried and ground magic mushrooms mixed with food (like chocolate), and then consumed. \n\nMany people prefer eating their magic mushrooms as an edible as they have a pungent, earthy flavor that many find unpleasant. Adding your shrooms to chocolate makes the experience more palatable - but chocolate does to just about everything! \n\n### What are the Effects of Magic Mushroom Chocolates?\n \nConsuming psilocybin will induce a psychedelic experience (hence the name psychedelics given to this category of mind-altering substance) that brings on changes in perception and an altered state of consciousness. \n\nHere’s how the process works: The psilocybin in magic mushrooms is converted to psilocin in the body which influences serotonin levels in the brain and creates an altered state of consciousness.\n\nThe effects of shrooms generally take 20 to 40 minutes to kick in and can last up to around 6 hours – the amount of time it takes for psilocin to be metabolized in the body. \n\n![How to make magic mushroom chocolate](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_03_31_at_12_58_02_PM_9ba6e9aed4.png)\n\nWhen eating magic mushroom chocolates, we suggest waiting a half an hour before ingesting more chocolate to assess the intensity of your trip.\n\nMagic mushrooms can induce a variety of experiences, from fits of giggles to a powerful emotional or even spiritual awakening. People report feeling euphoric and more connected to the world around them.\n\n### How to Make Magic Mushroom Chocolates\n\nMaking magic mushroom chocolates at home is easy. The hardest part is accurately dosing the chocolates, but the best way to ensure that you don’t overindulge is to eat a small portion and wait to feel the effects. \n\n### What is the Dosage of Homemade Magic Mushroom Chocolates?\n\nA low dose of psilocybin mushrooms is considered to be one gram or less. A \"heroic dose\", which is a large dose, is five grams. When grinding your mushrooms for your chocolate, keep this in mind as you will want to estimate the amount of psilocybin per chocolate. Purchasing a digital scale will help you more accurately assess the amount of mushrooms and keep in mind that potency varies from strain to strain.\n\nIdeally, your magic mushroom chocolates should be measured into grams. If you follow the directions above, you will have 28 evenly sized chocolate pieces made from 1 ounce of magic mushrooms (28 grams). Therefore, each chocolate should contain close to 1 gram of psilocybin mushroom powder. \n\n![How to make magic mushroom chocolate](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_03_31_at_12_59_12_PM_93c9afb758.png)\n\nHowever, this process may not be exact, and you should use caution when consuming your homemade chocolates. Start by eating one-half of a chocolate and waiting 30-40 minutes before consuming more. \n\n### Supplies to Make Magic Mushroom Chocolates\n\n- A grinder (a coffee grinder or blender will work)\n- 12 ounces chocolate chips, melting wafers, or chocolate bar\n- 1 ounce dried psilocybin mushrooms\n- A pot \n- A chocolate mold (optional – use a banking sheet as an alternative)\n- Metal or pyrex bowl \n\n### Steps for Making Magic Mushroom Chocolates\n\n- 1.) Grind the psilocybin mushrooms to a fine powder \n- 2.) Melt the chocolates by double boiling – fill a pot halfway with water and bring to a boil, then place your bowl over the pot, add the chocolates, and melt \n- 3.) Remove chocolate from heat and allow to cool slightly to the touch\n- 4.) Mix the powdered mushrooms into the cooled chocolate \n- 5.) Stir until the mixture is evenly distributed and there are no clumps\n- 6.) Pour the mixture into molds or onto a baking sheet lined with wax paper\n- 7.) Let the mixture cool until the chocolate hardens\n- 8.) If the chocolate was poured into a pan, cut into 28 even sections\n\nNow that you know the ins and outs of magic mushrooms, and how to make a delicious chocolate treat – you can try this “miracle compound” out for yourself. Remember, a good trip can often relate to your environment – be sure to eat your chocolates in a safe, welcoming place and enjoy the ride! \n\n### Get Your Medical Document & Purchase Medical Cannabis\n\nIt's easy to get your medical document with the online [Telehealth service HelloMD](https://hellomd.com/get-started). Register, pay, and receive an online medical consultation with a licensed practitioner and start purchasing medical cannabis today.\n\n*Note: This article is intended for people living in areas where psilocybin is decriminalized. \n\n\n\n\n\n\n\n \n \n","image":{"childImageSharp":{"fluid":{"base64":"data:image/png;base64,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","aspectRatio":1.5037593984962405,"src":"/static/7f32809a56944b7d7516dadc4c1a44ed/ee604/04fefb3824c7c52a92a3b510edbe056a.png","srcSet":"/static/7f32809a56944b7d7516dadc4c1a44ed/69585/04fefb3824c7c52a92a3b510edbe056a.png 200w,\n/static/7f32809a56944b7d7516dadc4c1a44ed/497c6/04fefb3824c7c52a92a3b510edbe056a.png 400w,\n/static/7f32809a56944b7d7516dadc4c1a44ed/ee604/04fefb3824c7c52a92a3b510edbe056a.png 800w,\n/static/7f32809a56944b7d7516dadc4c1a44ed/f3583/04fefb3824c7c52a92a3b510edbe056a.png 1200w","srcWebp":"/static/7f32809a56944b7d7516dadc4c1a44ed/58556/04fefb3824c7c52a92a3b510edbe056a.webp","srcSetWebp":"/static/7f32809a56944b7d7516dadc4c1a44ed/61e93/04fefb3824c7c52a92a3b510edbe056a.webp 200w,\n/static/7f32809a56944b7d7516dadc4c1a44ed/1f5c5/04fefb3824c7c52a92a3b510edbe056a.webp 400w,\n/static/7f32809a56944b7d7516dadc4c1a44ed/58556/04fefb3824c7c52a92a3b510edbe056a.webp 800w,\n/static/7f32809a56944b7d7516dadc4c1a44ed/99238/04fefb3824c7c52a92a3b510edbe056a.webp 1200w","sizes":"(max-width: 800px) 100vw, 800px"}}}}},{"node":{"id":"Article_3918-markdown","title":"What is 'California Sober'?  ","slug":"what-is-california-sober","content":"Welcome to the new era of ['California Sober'](https://www.vice.com/en/article/a3xvga/california-sober-quitting-drugs-alcohol-weed), and it's not entirely sober, but it's gaining in popularity with the younger generation. I'll give you a hint - Gen Z and Millennials are trading alcoholic cocktails and cocaine for mocktails, canna-beverages, and consciousness-expanding psychedelics.\n\nSome people claim that this is the new 'healthy' lifestyle that includes mood-altering substances but without the dire health consequences of alcohol. \n\nSo what exactly is **California sober**, and where did this all begin? \n\nLet's break it down and discuss why this movement isn't just a trend but the future of cannabis consumption and modern 'sobriety' in America.  \n\n![California sober is popular with Gen Z and Millenials](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_03_18_at_4_02_23_PM_ed8a66fc67.png)\n\n### What is 'California Sober'?\n\nThe term California sober is much more ambiguous than any official medical term related to sobriety. Generally, being Cali sober means, you are giving up all drugs and alcohol and instead only using cannabis, and possibly psychedelics, in moderation. A California sober person will avoid harder drugs, [like opioids](https://www.hellomd.com/articles/the-science-behind-why-marijuana-is-safer-than-opioids) and [alcohol](https://www.hellomd.com/articles/can-cannabis-be-a-healthier-substitute-for-alcohol). \n\nSome Cali sober people may choose to use additional mind-altering substances such as LSD, while others will only consume marijuana. But the fact is, being California sober means something different to everyone involved. \n\nWhile celebrities and everyday folk are moving toward a California sober way of life, there are some important distinctions to keep in mind before following suit. \n\n- California sober is not a recommended alternative for those with drug and alcohol addictions. \n- Some people may exclusively use cannabis, while others may include psychedelics. \n- Being California Sober doesn't necessarily mean you're quitting drinking forever. It can just mean a cutback in regular consumption. \n\nRegardless of your end goal, making a move to California sober has proved to have a positive impact on the lives of many. The term has now been identified as an aspirational lifestyle and is increasingly popular.\n\n![CANN is a cannabis beverage](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_03_18_at_4_01_06_PM_ec4bb05155.png)\n\n### Why Cannabis Use is Growing\n\nCannabis is losing its stigma and is quickly becoming mainstream. As new products and research are available, new consumers are flocking to marijuana and throwing away the stoner stereotype.\n\nThe reality is that cannabis can help with [many health conditions](https://hellomd.com/articles/can-marijuana-help-with-chronic-pain-anxiety-and-insomnia), but it's proving especially useful for those seeking an elevated mindset without the hangover, liver damage, or possibility of overdose. Cannabis beverages by companies like [CANN](https://www.drinkcann.com/) are giving consumers new low-dose alternatives for drinking **THC** and **CBD**, and people are loving it.\n\nNowadays, you can curate strains and products to fit your unique, specified needs. You can [look at the massive increase in cannabis beverage sales](https://www.globenewswire.com/news-release/2022/01/14/2367143/0/en/Global-Cannabis-Beverages-Market-to-Reach-US-2-Billion-by-the-Year-2026.html) over the past years and see demand is rapidly growing for alcohol alternatives. \n\nWith new studies related to **endocannabinoids**, trichomes, [terpenes](https://hellomd.com/articles/what-are-cannabis-terpenes-and-how-do-they-work), and more — we're unlocking a new world of diversity for modern cannabis consumers. \n\nSo not only is it easier to access cannabis, it's easier (and more exciting) to intertwine it into your daily life. You can seamlessly ditch the alcohol and switch to cannabis without anyone noticing — or caring!\n\n![Hello1-min (32).png](https://hellomd-cms.s3.us-west-2.amazonaws.com/Hello1_min_32_02de075651.png)\n\n### COVID Increased Alcohol Consumption\n\nThe pandemic rocked our daily lives, causing us to stay locked indoors for extended periods of time. It also boosted alcohol consumption to an unhealthy level. \n\nA study published in [Hepatology](https://aasldpubs.onlinelibrary.wiley.com/doi/full/10.1002/hep.32272) found that binge drinking among Americans increased by 21% during the COVID-19 pandemic. \n\nAdditionally, this sustained level of drinking can result in a 19 to 35 percent increase in mortality if continued.  \n\nAs the pandemic wanes, we're now seeing people return to their normal lives. But many are now looking for ways to slow down or cut out their pandemic-level alcohol intake without going stone-cold sober. \n\nThose looking for an alternative to a glass of wine (or three) can rejoice at the opportunity modern marijuana offers. Cannabis can ease the transition of alcohol for those who have grown used to drinking excessively. \n\n![Weed is replacing alcohol](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_03_18_at_4_06_36_PM_2145d5c51f.png)\n\n### What's Next for the California Sober Trend? \n\nThe timing of the California Sober craze appears to be perfect, but where is it headed? We've already touched on the popularity of cannabis beverages, but [according to NielsenIQ](https://nielseniq.com/global/en/insights/analysis/2018/rise-of-no-and-low-alcohol/), sales of non-alcoholic drinks rose 33.2% in 2021 as well. \n\nPeople understand that alcohol is at the core of socialization in our modern world, but the abundance of technology and a marketplace filled with new alcohol alternatives is helping us reshape what 'sobriety' really means. \n\nWhether we call it California sober or a \"healthier social life,\" this trend is one we can all get behind. It's a momentous shift toward cleaner living and longevity.\n\nAnd the best part is that cannabis is at the center of it all. \n\n### Get Your Medical Document & Purchase Medical Cannabis\n\nIt's easy to get your medical document with the online [Telehealth service HelloMD](https://hellomd.com/get-started). Register, pay, and receive an online medical consultation with a licensed practitioner and start purchasing medical cannabis today.","image":{"childImageSharp":{"fluid":{"base64":"data:image/png;base64,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","aspectRatio":1.5037593984962405,"src":"/static/41d2269d4f146babd11cf59aea371fdc/ee604/e9f19a7bfd5f713af3c80084307bdf0a.png","srcSet":"/static/41d2269d4f146babd11cf59aea371fdc/69585/e9f19a7bfd5f713af3c80084307bdf0a.png 200w,\n/static/41d2269d4f146babd11cf59aea371fdc/497c6/e9f19a7bfd5f713af3c80084307bdf0a.png 400w,\n/static/41d2269d4f146babd11cf59aea371fdc/ee604/e9f19a7bfd5f713af3c80084307bdf0a.png 800w,\n/static/41d2269d4f146babd11cf59aea371fdc/f3583/e9f19a7bfd5f713af3c80084307bdf0a.png 1200w","srcWebp":"/static/41d2269d4f146babd11cf59aea371fdc/58556/e9f19a7bfd5f713af3c80084307bdf0a.webp","srcSetWebp":"/static/41d2269d4f146babd11cf59aea371fdc/61e93/e9f19a7bfd5f713af3c80084307bdf0a.webp 200w,\n/static/41d2269d4f146babd11cf59aea371fdc/1f5c5/e9f19a7bfd5f713af3c80084307bdf0a.webp 400w,\n/static/41d2269d4f146babd11cf59aea371fdc/58556/e9f19a7bfd5f713af3c80084307bdf0a.webp 800w,\n/static/41d2269d4f146babd11cf59aea371fdc/99238/e9f19a7bfd5f713af3c80084307bdf0a.webp 1200w","sizes":"(max-width: 800px) 100vw, 800px"}}}}},{"node":{"id":"Article_3904-markdown","title":"What Is San Pedro: Psychedelics 101","slug":"what-is-san-pedro-psychedelics-101","content":"Psychedelics like [LSD](https://hellomd.com/articles/what-is-lsd-psychedelics-101) and [magic mushrooms](https://hellomd.com/articles/what-is-psilocybin-psychedelics-101) are well-known in pop culture and are now studied for their potential therapeutic properties, but what about San Pedro (*Trichocereus/Echinopsis pachanoi*)?\n\nThis plant-based psychedelic is one of several cacti producing [mescaline](https://www.drugs.com/illicit/mescaline.html)— the psychoactive compound [that inspired](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC381240/) the term “psychedelic.” Researchers continue to unlock the potential of **San Pedro**, showing its possible applications in the mental health system.  \n\n![The san pedro cactus](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_03_11_at_12_20_03_PM_ceadbe1d2c.png)\n\n### What Is San Pedro?\nSan Pedro is a cactus native to the Andes Mountains. This cactus contains mescaline and other derivatives of [phenethylamine](https://en.wikipedia.org/wiki/Phenethylamine), yielding hallucinogenic properties. Although many Americans are unfamiliar with San Pedro, this plant has [a long history](https://pubmed.ncbi.nlm.nih.gov/16625512/) as an essential element of spiritual ceremonies for thousands of years. \n\nUsed by several pre-Columbine civilizations, the indigenous use of San Pedro for healing and psychedelic purposes remains part of the culture in Andean shamanism to this day. It is now being studied for [potential therapeutic benefits based on its unique effects](https://thethirdwave.co/psychedelics/san-pedro/). \n\n![The san pedro cactus](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_03_11_at_12_22_15_PM_1aab20baf9.png)\n\n### What Are the Effects of San Pedro?\nMuch like other psychedelics, San Pedro creates an intense and powerful psychedelic experience, leading to extravagant visuals, such as whirlpools of colored light, kaleidoscopic patterns, and ghostlike outlines of people. However, many people are surprised how relaxed and in control they feel. \n\nSan Pedro is also [empathogenic](https://en.wikipedia.org/wiki/Empathogen%E2%80%93entactogen), much like MDMA — meaning it creates a sense of oneness, relatedness, and emotional openness. Although it’s common to experience specific effects, everyone will have a unique experience.\n\n![Psychedelic visuals are common with san pedro](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_03_11_at_12_23_22_PM_05e45e4da7.png)\n\nSome of the most common effects include:\n\n- Strong visual effects, especially at high doses\n- Altered sense of time \n- Altered thinking processes\n- Greater self-awareness and feelings of connection\n- Potential nausea \n- Possible anxiety and paranoia\n\nMany agree it's a beautiful, enjoyable, and even mystical experience — but adverse effects are also possible. For example, when San Pedro first hits, you may feel dizzy, and as you come up, nausea, vomiting, and perspiration are also relatively common. \n\nA bad trip often results among those who ignore the importance of [set and setting](https://hellomd.com/articles/exploring-mind-bending-psychedelics-psilocybin-and-lsd) and those who have a history of mental illness. \n\n### What Are the Therapeutic Benefits of San Pedro?\nSan Pedro’s healing capabilities are primarily anecdotal, but of the claims reported, San Pedro is a potentially powerful therapeutic substance. That said, several studies, reviews, and surveys have been published, including [a 2021 self-reported questionnaire](https://pubs.acs.org/doi/10.1021/acsptsci.1c00018). Four hundred fifty-two anonymous individuals were asked about the mental health benefits attributed to mescaline.\n\n![The san pedro cactus](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_03_11_at_12_24_54_PM_95f39013e0.png)\n\nOf the respondents with a history of post-traumatic stress disorder, depression, anxiety, and substance use disorder, 68-86% reported improvement following their experience with mescaline. Additionally, 30-50% of respondents rated their mescaline experience as the single most or in their top five for spiritually significant experiences of their lives. \n\nThe [University of Melbourne published an article](https://pursuit.unimelb.edu.au/articles/psychedelic-medicine-a-mental-health-game-changer), “Psychedelic Medicine: A Mental Health Game Changer?” \n\nThis piece highlighted the rising number of studies on plant-derived psychotropic compounds for psychiatric disorders, including San Pedro. After conducting an analysis, researchers concluded that medicinal psychedelics have a significant effect on symptoms of depression in the short term and help patients with a mood disorder in the long term. \nAlthough more research is required, the current data and available case studies are compelling. \n\n### Are There Any Risks Associated With San Pedro?\n\nThose who plan to take San Pedro must be prepared for a long trip. The effects of San Pedro can last as long as eight to 12 hours. So, like other psychedelics, preparation is critical. For example, when taking San Pedro, you will experience powerful shifts in your consciousness, resulting in strong emotions. \n\nIf feelings of anxiety creep in, the effects are too long-lasting not to have something available that comforts you — especially if you’re using San Pedro in contexts that may not be safe. Again, this is why set and setting are so imperative. \n\n![The san pedro cactus](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_03_11_at_12_26_03_PM_89ee306651.png)\n\nSince research is limited, not much is known about San Pedro’s potential harm. Although there isn’t a known lethal dose, certain individuals may be at risk of complications, including those with high blood pressure, heart or colon issues, diabetes, or a mental illness. It is also not recommended that you combine San Pedro with MAOIs, including the antidepressants tranylcypromine and phenelzine.\n\n### Is San Pedro Legal?\n\nIn the United States, [mescaline is a Schedule I drug](https://www.dea.gov/sites/default/files/2020-06/Peyote%20and%20Mescaline-2020_0.pdf), defined as having no currently accepted medical use and a high potential for abuse. However, only peyote is specifically classified as a controlled substance of the cacti containing mescaline.\n \nProsecutions are rare but do happen — and in some jurisdictions, “entheogenic plants” are being decriminalized. In 2019, Oakland, CA, became the second American city to legalize psilocybin and other entheogenic plants and fungi after people spoke out about how psychedelics helped them overcome addiction, depression, and post-traumatic stress disorder. The actions taken are paving the way for psychedelic-assisted therapy.\n\nIn other areas of the globe, such as the Netherlands and the UK, the situation is similar. Certain psychedelics are uncontrolled and freely available, whereas others are still prohibited. \nIn the UK, psilocybin is illegal, but San Pedro is not. \n\nThe Netherlands is Europe's most psychedelic-friendly country — psilocybin truffles are legal, whereas drugs like LSD are not. \nIn New Zealand, Germany, and other countries, it is legal to cultivate San Pedro but illegal to use the substance recreationally. \nIn Ukraine, the government excluded San Pedro from the list of illicit drugs.\n\nSan Pedro is legal in the Andean countries, such as Bolivia, Peru, and Ecuador, even as a psychedelic.\n\n![The san pedro cactus](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_03_11_at_12_27_28_PM_ff632375fa.png)\n\n### Where Can I Legally Seek San Pedro Treatment?\n\nEfforts to decriminalize “natural psychedelics” are underway in the United States, with Oakland and Santa Cruz leading. However, **San Pedro is not currently legal on a federal level**. San Pedro ceremonies are legal in Peru, and while retreat centers offer various experiences, not all providers are equal. Personal research is crucial. \n\n### Get Your Medical Document & Purchase Medical Cannabis\nIt’s easy to get your medical document with the online [Telehealth service HelloMD](https://hellomd.com/get-started). Register, pay, and receive an online medical consultation with a licensed practitioner and start purchasing medical cannabis today","image":{"childImageSharp":{"fluid":{"base64":"data:image/jpeg;base64,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","aspectRatio":1.3333333333333333,"src":"/static/64f031470389e80f7f57fa2bda9eebf3/14b42/f44bdfac5f864a6ab11b795524ce238a.jpg","srcSet":"/static/64f031470389e80f7f57fa2bda9eebf3/f836f/f44bdfac5f864a6ab11b795524ce238a.jpg 200w,\n/static/64f031470389e80f7f57fa2bda9eebf3/2244e/f44bdfac5f864a6ab11b795524ce238a.jpg 400w,\n/static/64f031470389e80f7f57fa2bda9eebf3/14b42/f44bdfac5f864a6ab11b795524ce238a.jpg 800w,\n/static/64f031470389e80f7f57fa2bda9eebf3/47498/f44bdfac5f864a6ab11b795524ce238a.jpg 1200w,\n/static/64f031470389e80f7f57fa2bda9eebf3/0e329/f44bdfac5f864a6ab11b795524ce238a.jpg 1600w,\n/static/64f031470389e80f7f57fa2bda9eebf3/f0ad3/f44bdfac5f864a6ab11b795524ce238a.jpg 3813w","srcWebp":"/static/64f031470389e80f7f57fa2bda9eebf3/58556/f44bdfac5f864a6ab11b795524ce238a.webp","srcSetWebp":"/static/64f031470389e80f7f57fa2bda9eebf3/61e93/f44bdfac5f864a6ab11b795524ce238a.webp 200w,\n/static/64f031470389e80f7f57fa2bda9eebf3/1f5c5/f44bdfac5f864a6ab11b795524ce238a.webp 400w,\n/static/64f031470389e80f7f57fa2bda9eebf3/58556/f44bdfac5f864a6ab11b795524ce238a.webp 800w,\n/static/64f031470389e80f7f57fa2bda9eebf3/99238/f44bdfac5f864a6ab11b795524ce238a.webp 1200w,\n/static/64f031470389e80f7f57fa2bda9eebf3/7c22d/f44bdfac5f864a6ab11b795524ce238a.webp 1600w,\n/static/64f031470389e80f7f57fa2bda9eebf3/a4d75/f44bdfac5f864a6ab11b795524ce238a.webp 3813w","sizes":"(max-width: 800px) 100vw, 800px"}}}}},{"node":{"id":"Article_3889-markdown","title":"What is Ayahuasca: Psychedelics 101","slug":"what-is-ayahuasca-psychedelics-101","content":"*\"There are all kinds of ways to challenge ourselves. Some people do it by climbing a mountain or scuba diving. The most profound and challenging ordeal is to drink ayahuasca. It is in a way the ultimate adventure.\"* \n\n*- Graham Hancock, British writer, and journalist*\n\n-------------\n\nAyahuasca is a psychedelic medicine indigenous tribes have used for thousands of years. Today, it's garnering the attention of Westerners from all walks of life - from the Silicon Valley elite to urban psychonauts who are on a quest for deeper self-awareness and personal healing. \n\nThey're venturing near and far to drink ayahuasca in 'ceremony', often traveling to retreat centers in the South American rainforest. Films like [The Reality of Truth](https://www.imdb.com/title/tt2056751/) take us on trips deep into Peru to explore how plant medicine may help us access deep states of conscious awareness. \n\n![Ayahuasca is made from a vine in the Amazon](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_21_at_2_08_46_PM_4adb853f9e.png)\n\nBut it goes past the desire to expand consciousness. In recent years, people who struggle with severe depression, anxiety, PTSD, chronic pain, addiction, and even bipolar disorder claim that ayahuasca has immense therapeutic benefits. As a result, ayahuasca is now being studied, along with psychedelics, by research centers worldwide for its medicinal potential. \n\nWhat is it about ayahuasca that has such a profound impact on people? Could this plant-based psychedelic be used as a medicine for optimal health?\n\n### What Is Ayahuasca?\n\n![Ayahuasca is a vine that grows in the Amazon](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_21_at_2_07_25_PM_2e266429dc.png)\n\n\nThe \"vine of the spirits\" – ayahuasca has been used for therapeutic and spiritual purposes for centuries. The indigenous people of Peru, Guyana, Bolivia, Brazil, Columbia, and Ecuador began using ayahuasca as a sacrament in the 1930s. Today, its properties are studied for its positive impact on [mental health disorders, autoimmune disorders, and addiction](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343205/). A recent study showed promise on ayahuasca's immediate [antidepressant effect](https://www.biorxiv.org/content/10.1101/103531v1) for those suffering from severe depression.\n\nAyahuasca is ingested as a brew or a tea made from the banisteriopsis caapi vine, which contains DMT, and the psychotria viridis leaf, which contains plant-based monoamine oxidase inhibitors (MAOIs). MAOIs extend the effect of DMT, making ayahuasca a long-lasting and powerful psychedelic. Most often, ayahuasca is made from plants in the Amazon, although people outside of South America also cultivate these psychedelic plants. Interestingly, DMT is a naturally occurring chemical found in small amounts in the human brain. \n\n![Ayahuasca is a brew or tea made from vines and a specific leaf](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_21_at_2_08_59_PM_6d97a5ca77.png)\n\n\n### What Are the Effects of Ayahuasca?\nWhen taken in controlled doses, [DMT significantly alters electrical brain activity]( https://www.sciencedaily.com/releases/2019/11/191119075305.htm), although the effects associated with DMT are different from other psychedelics, including LSD and psilocybin.\n\n[A study published in 2019](https://www.nature.com/articles/s41598-019-51974-4) was the first to show how DMT impacts waking brain waves, causing subjects to experience an immersive \"waking-dream\". Those who take DMT, specifically ayahuasca, often report intense hallucinations and emotional experiences, leading to significant breakthroughs. As scientists describe this experience, \"it's like dreaming, but with your eyes open.\"\n\nAyahuasca has been shown to [modulate brain activity]( https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895707/); impacting key neurotransmitters and gene expression. Ayahuasca may not just treat psychology and emotional well-being, but it may also [support brain health](https://www.healthline.com/nutrition/ayahuasca#benefits), protecting brain cells while stimulating new cell growth.\n\n### What Are the Therapeutic Benefits of Ayahuasca?\n\n![The Ayahuasca vine](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_21_at_2_12_44_PM_d8b6832f71.png)\n\nThe neurological effects of ayahuasca are both vast and complex. For example, there is evidence that [ayahuasca alters thinking style](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182612/), impacting areas such as judgment and reactivity. This suggests that consumers may experience greater acceptance of their thoughts and feelings, specifically benefiting those who have persistent negative, unhealthy thoughts – such as those with depression.\n\nAs [stated by Cambridge University Press](https://www.cambridge.org/core/journals/psychological-medicine/article/rapid-antidepressant-effects-of-the-psychedelic-ayahuasca-in-treatmentresistant-depression-a-randomized-placebocontrolled-trial/E67A8A4BBE4F5F14DE8552DB9A0CBC97), when individuals suffering from treatment-resistant depression take ayahuasca, they can experience rapid antidepressant effects. Published in Psychological Medicine, this study concluded that when ayahuasca is dosed within an appropriate setting, it holds safe, and therapeutic value for those with depression.\n\nThe same is true for PTSD, as ayahuasca has become a popular alternative among those who have tried traditional treatments, such as medication and therapy, without much success. \n\n\n![People take ayahuasca for a variety of reasons, including to heal past trauma](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_21_at_2_10_34_PM_d2799fe91f.png)\n\n\nRegarding addiction, ayahuasca may exert [significant anti-addictive properties]( https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773875/), based on how it influences dopamine and serotonin levels while interfering with synaptic plasticity, which contributes to learning and memory. Psychological insights also increase, helping individuals process repressed trauma while enhancing their decision-making skills.\n### Are There Any Risks Associated with Ayahuasca?\nTaking ayahuasca can be a very intense experience, and in some cases, individuals may experience psychological stress, higher blood pressure, and elevated heart rate. \n\n![Ayahuasca is most often in the form of a tea or thick brew](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_21_at_2_14_22_PM_8d71fe5b5a.png)\n\nWhen consuming ayahuasca, it is common that consumers 'purge', or vomit. It is also known to cause sweating, shaking, crying, and even defecation. Often, purging is looked upon as a cleansing of the body, mind, and spirit. To many, it's seen as a necessary part of the process when consuming this psychedelic. Many shamans consider the purge an essential part of one's journey and spiritual awakening.\n\nFor the most part, when taken in a responsible, controlled environment, ayahuasca is safe. As [stated by York University](https://trauma.blog.yorku.ca/2019/11/ayahuasca-and-its-potential-to-treat-ptsd/), this substance is most dangerous when individuals have a pre-existing illness, such as a heart condition. \n\nIn the few reported cases of death, such existing conditions are believed to play a role and other [ possible drug interactions](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007657/). Ayahuasca is not intended to be taken with other recreational drugs, antidepressants, nicotine, or caffeine. There has never been a death during a clinical study.\n### Where Can I Legally Seek Treatment with Ayahuasca?\nAyahuasca is currently illegal to consume, sell, possess, import, or distribute in the United States. However, there are judicially granted exceptions for select churches, and in some cases, these legal battles reached the Supreme Court. There are similar exceptions being made in other Western countries, including Canada.\n\nIf you seek a retreat center outside of the United States that offers ayahuasca ceremonies, it is vital to do your homework.\n\n### Get Your Medical Document & Purchase Medical Cannabis\n\nIt's easy to get your medical document with the online [Telehealth service HelloMD](https://hellomd.com/get-started). Register, pay, and receive an online medical consultation with a licensed practitioner and start purchasing medical cannabis today.\n\n","image":{"childImageSharp":{"fluid":{"base64":"data:image/png;base64,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","aspectRatio":1.5037593984962405,"src":"/static/279f4da01caf1c7149a0b60a9c94e9a9/ee604/a430c766f206edb4581dc1fa4a3245ea.png","srcSet":"/static/279f4da01caf1c7149a0b60a9c94e9a9/69585/a430c766f206edb4581dc1fa4a3245ea.png 200w,\n/static/279f4da01caf1c7149a0b60a9c94e9a9/497c6/a430c766f206edb4581dc1fa4a3245ea.png 400w,\n/static/279f4da01caf1c7149a0b60a9c94e9a9/ee604/a430c766f206edb4581dc1fa4a3245ea.png 800w,\n/static/279f4da01caf1c7149a0b60a9c94e9a9/f3583/a430c766f206edb4581dc1fa4a3245ea.png 1200w","srcWebp":"/static/279f4da01caf1c7149a0b60a9c94e9a9/58556/a430c766f206edb4581dc1fa4a3245ea.webp","srcSetWebp":"/static/279f4da01caf1c7149a0b60a9c94e9a9/61e93/a430c766f206edb4581dc1fa4a3245ea.webp 200w,\n/static/279f4da01caf1c7149a0b60a9c94e9a9/1f5c5/a430c766f206edb4581dc1fa4a3245ea.webp 400w,\n/static/279f4da01caf1c7149a0b60a9c94e9a9/58556/a430c766f206edb4581dc1fa4a3245ea.webp 800w,\n/static/279f4da01caf1c7149a0b60a9c94e9a9/99238/a430c766f206edb4581dc1fa4a3245ea.webp 1200w","sizes":"(max-width: 800px) 100vw, 800px"}}}}},{"node":{"id":"Article_3886-markdown","title":"What is Psilocybin: Psychedelics 101","slug":"what-is-psilocybin-psychedelics-101","content":"After several decades of being ignored by mainstream society, psychedelic mushrooms, known as [psilocybin](https://en.wikipedia.org/wiki/Psilocybin), are being embraced for their remarkable healing qualities. Every day seems to bring new reports about the abundant therapeutic benefits of psilocybin — reports often generated by respected research institutions, such as [Johns Hopkins](https://www.hopkinsmedicine.org/psychiatry/research/psychedelics-research.html) and the [Imperial College London](https://www.imperial.ac.uk/psychedelic-research-centre/). It's time to start paying attention to psilocybin and how it may disrupt our mental healthcare system.\n\n### What is Psilocybin?\n\n![Untitled45-min.png](https://hellomd-cms.s3.us-west-2.amazonaws.com/Untitled45_min_f93a11a214.png)\n\nPsilocybin, also known as [magic mushrooms](https://www.drugs.com/illicit/psilocybin.html), is a chemical compound found within certain mushrooms. It is also one of the most well-known plant-based psychedelic drugs. When psilocybin is consumed, it turns into psilocin, which has psychoactive properties which result in a psychedelic experience for the consumer. \n\nMore than 180 mushrooms contain this compound, with [psilocybe cubensis](https://pt.wikipedia.org/wiki/Psilocybe_cubensis) being probably the most well-known. In fresh or dried form, the mushrooms are usually mixed into food or brewed into tea, although some research labs process the mushrooms to precisely measure the psilocybin dosage.\n\n### What are the Effects of Psilocybin?\n\n![Psilocybin can cause hallucinations](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_14_at_1_36_40_PM_ba92eae610.png)\n\nThe word \"psychedelic\" is commonly associated with changes in perception and an altered state of consciousness. Consumers report generally enhanced sensory experiences, including visual halos and geometric patterns, time dilation, and a physical sense of relaxation. \n\n[Synesthesia](https://www.webmd.com/brain/what-is-synesthesia#:~:text=Synesthesia%20is%20when%20you%20hear,street%22%20and%20taste%20citrus%20fruit.) is also commonly reported. This experience is a blending of sense experiences so that music may appear visual or physical sensations are felt as sounds. \n\nMost importantly, however, psilocybin generates powerful emotional and psychological experiences. These tend to be strongly positive, often described as euphoria, wonder, or delight, and most people also describe feeling a new sense of [connection with the universe, or even God](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478303/).\n\n### What are the Therapeutic Benefits of Psilocybin?\n\n![Medical labs are studying the effects of psilocybin on mental health and more](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_14_at_1_33_42_PM_fbe99427b8.png)\n\nThe emotionally uplifting experience brought about by psilocybin has many applications for mental and physical health. It has also been demonstrated to effectively treat [depression](https://psychedelicstoday.com/2019/11/13/psilocybin-depression/), [PTSD](https://med.nyu.edu/departments-institutes/population-health/divisions-sections-centers/medical-ethics/education/high-school-bioethics-project/learning-scenarios/ptsd-treatment-psychedelics), [anxiety](https://thethirdwave.co/psychedelics/shrooms/), [headaches](https://maps.org/news/media/5967-new-york-magazine-psychedelic-mushrooms-cured-my-cluster-headaches), and [spiritual alienation](https://maps.org/news/media/2619-hopkins-researchers-study-therapeutic-use-of-psilocybin-in-magic-mushr). \n\n![Psilocybin is being used to treat depression and PTSD ](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_14_at_1_34_08_PM_56451fbfc8.png)\n\nIn September 2019, [Johns Hopkins University](https://www.hopkinsmedicine.org/psychiatry/research/psychedelics-research.html#:~:text=In%20a%20small%20study%20of,and%20half%20of%20study%20participants) announced the launch of its Center for Psychedelic and Consciousness Research. It is pursuing psilocybin-based treatments for depression, addiction, PTSD, Alzheimers, and chronic Lyme Disease. In late January 2020, [Dr. Stephen Ross](https://nyulangone.org/doctors/1083825590/stephen-ross), associate professor of psychiatry in the [Department of Psychiatry at NYU Langone Health](https://www.cnn.com/2020/01/28/health/magic-mushrooms-psilocybin-cancer-patients-study-wellness/index.html), reported findings that \"strongly suggest that psilocybin therapy is a promising means of improving the emotional, psychological, and spiritual well-being of patients with life-threatening cancer.\"\n\n![Psilocybin has many positive effects and some people feel more connected to themselves and the universe](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_14_at_1_40_03_PM_b462733990.png)\n\n### Are there any Risks Associated with Psilocybin?\n\nWhile medical science has not identified any long-term adverse effects, some people experience nausea, confusion, fear, or other negative emotions while under the influence of psilocybin. \n\nHowever, these negative experiences are often eased or go away when there is clinical assistance, or a psychedelic guide present, to help the consumer through their psychedelic journey. According to the [University of Maryland Center for Substance Abuse Research](https://cesar.umd.edu/), there is no evidence that psilocybin is physically or psychologically addictive.\n\n![Psilocybin is not yet legal in the States but is decriminalized in some counties](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_14_at_1_41_10_PM_3c18f9c817.png)\n\n### Is Psilocybin Legal?\nYes and no; Like marijuana, psilocybin is illegal at the federal level in the U.S., classified as a [Schedule 1 substance under the Controlled Substances Act](https://www.dea.gov/drug-information/drug-scheduling#:~:text=Schedule%20I%20drugs%2C%20substances%2C%20or,)%2C%20methaqualone%2C%20and%20peyote.). \nHowever, some local jurisdictions are passing laws for the decriminalization of psilocybin, and research institutions can obtain legal waivers. In 2019, Denver and Oakland decriminalized psychedelic plant-based substances, including psilocybin. \n\n[Legalization measures](https://www.theatlantic.com/health/archive/2019/05/mushroom-law/589192/) are expected to be brought before the legislatures in California and Oregon in 2020. In Brazil, Jamaica, The Netherlands, and Vietnam, psilocybin use is entirely legal.\n\n![Untitled48-min (1).png](https://hellomd-cms.s3.us-west-2.amazonaws.com/Untitled48_min_1_b2277d3a13.png)\n\n### Are there any Drug Interactions with Psilocybin?\n\nThe most important safety consideration when taking psychedelic mushrooms is to make sure that whoever harvested the mushrooms is an expert in making the correct identification. Some non-psychedelic types of mushrooms look similar and can be toxic. It is also wise to [avoid mixing psychoactive drugs](https://adf.org.au/drug-facts/psilocybin/) in general. For that reason, you should avoid using psilocybin with other drugs such as ice, speed, or ecstasy. Similarly, you should not use psychedelic mushrooms if you take psychiatric medication.\n\n### Where Can I Legally Seek Psilocybin Treatment?\n\n![Untitled47-min.png](https://hellomd-cms.s3.us-west-2.amazonaws.com/Untitled47_min_3873062f74.png)\n\nCurrently, it is not legal to seek [psilocybin-assisted therapy](https://hellomd.com/articles/the-healing-powers-of-psychedelic-therapy) in the United States, although this may be changing as soon as 2023. Psilocybin is entirely legal in the Netherlands, and retreat centers welcome guests from all over the world. You can also look online to find psychedelic retreat centers, and many are located in Jamaica. \n\n### Get Your Medical Document & Purchase Medical Cannabis\n\nIt's easy to get your medical document with the online [Telehealth service HelloMD](https://hellomd.com/get-started). Register, pay, and receive an online medical consultation with a licensed practitioner and start purchasing medical cannabis today.","image":{"childImageSharp":{"fluid":{"base64":"data:image/png;base64,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","aspectRatio":1.5037593984962405,"src":"/static/aa3f24cd0fbb8dcc7f4f2c084658dea5/ee604/16d1208e15e70ee025530bf273054fb6.png","srcSet":"/static/aa3f24cd0fbb8dcc7f4f2c084658dea5/69585/16d1208e15e70ee025530bf273054fb6.png 200w,\n/static/aa3f24cd0fbb8dcc7f4f2c084658dea5/497c6/16d1208e15e70ee025530bf273054fb6.png 400w,\n/static/aa3f24cd0fbb8dcc7f4f2c084658dea5/ee604/16d1208e15e70ee025530bf273054fb6.png 800w,\n/static/aa3f24cd0fbb8dcc7f4f2c084658dea5/f3583/16d1208e15e70ee025530bf273054fb6.png 1200w","srcWebp":"/static/aa3f24cd0fbb8dcc7f4f2c084658dea5/58556/16d1208e15e70ee025530bf273054fb6.webp","srcSetWebp":"/static/aa3f24cd0fbb8dcc7f4f2c084658dea5/61e93/16d1208e15e70ee025530bf273054fb6.webp 200w,\n/static/aa3f24cd0fbb8dcc7f4f2c084658dea5/1f5c5/16d1208e15e70ee025530bf273054fb6.webp 400w,\n/static/aa3f24cd0fbb8dcc7f4f2c084658dea5/58556/16d1208e15e70ee025530bf273054fb6.webp 800w,\n/static/aa3f24cd0fbb8dcc7f4f2c084658dea5/99238/16d1208e15e70ee025530bf273054fb6.webp 1200w","sizes":"(max-width: 800px) 100vw, 800px"}}}}},{"node":{"id":"Article_3882-markdown","title":"What is LSD: Psychedelics 101","slug":"what-is-lsd-psychedelics-101","content":"For most people, knowledge of LSD is limited to pop culture references, especially those from the 1960s and 1970s counterculture. Thanks to portrayals in movies and television, even people who never have tried the drug know what an acid trip is. But there's so much more to LSD than these stereotyped images. A [modern view of LSD](https://hellomd.com/articles/exploring-mind-bending-psychedelics-psilocybin-and-lsd) shows how it is no longer a recreational drug but medicine that may help people treat depression, PTSD, addiction, and more.\n\n### What Is LSD?\n[Lysergic acid diethylamide]https://www.ncbi.nlm.nih.gov/books/NBK482407/) is better known as LSD. LSD is also commonly known as acid, L, tabs, Lucy, and doses. The semi-synthetic compound belongs to the psychedelic class of drugs derived from one of the active ingredients in [ergot](https://en.wikipedia.org/wiki/Ergot), a fungus found in tainted rye. \n\n![Albert Hofman the creator of LSD](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_13_at_12_22_50_PM_c008441aa3.png)\n\nLSD was synthesized in 1938 by Swiss chemist Albert Hofmann at the Sandoz laboratories in Basel, Switzerland. Initially, the intention for development was as a  [respiratory and circulatory stimulant](https://en.wikipedia.org/wiki/History_of_lysergic_acid_diethylamide#:~:text=The%20psychedelic%20drug%20(or%20entheogen,)%20laboratories%20in%20Basel%2C%20Switzerland.). After development, it was put on the shelves. It was not until five years later, when Hofman accidentally absorbed a small amount of the drug, that he discovered the psychedelic qualities of LSD. \n\n### What Are the Effects of LSD?\nHighly potent even in small doses, LSD varies in [its effects](https://www.drugs.com/illicit/lsd.html).\n\n![LSD alters the way we see the world](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_13_at_12_25_39_PM_9e7891f024.png)\n\n\n### Physiological\nPhysiological effects of LSD typically include pupil dilation, reduced appetite, wakefulness, increased heart rate, increased body temperature, and sweating.\n\n### Sensory\nLSD affects our sensory perception while distorting and heightening the senses. Many consumers report a sharper sense of smell, heightened taste, and a greater appreciation for sounds and particularly music. Some people experience synesthesia, where senses merge and vvid, colorful visions, and auditory hallucinations are common effects of LSD. Many people comment on LSD's ability to alter and expand consciousness and to [overide the default mode network](https://hellomd.com/articles/why-interrupting-the-default-mode-network-with-psychedelics-is-good-for-mental-health).\n\n![Hallucinations are common on LSD](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_13_at_12_23_52_PM_43d357b20e.png)\n\n\n### Psychological and Emotional\nHow LSD impacts people psychologically depends on the dose consumed and in part on the user's present mental state, emotions, and environment. Some claim to have [life-altering spiritual experiences](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478303/). \n\nAt low to moderate amounts, positive and neutral effects predominate. The possibility of a \"bad trip\" increases as dosage increases. Commonly reported effects include:\n\n**Positive:**\n- Creativity\n- Visual hallucinations\n- Ego dissolution\n- Sense of connectedness to the world\n- Euphoria\n\n**Neutral:**\n- Altered consciousness\n- Distorted sense of time\n- Inability to focus\n- Unusual thoughts\n\n**Negative:**\n- Paranoia\n- Anxiety\n- Overwhelming feelings\n- A sense of being lost in space and time\n\n![LSD blows open the doors of our perception](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_13_at_12_27_11_PM_4807104375.png)\n\n### Promising Therapeutic Uses From Past and Present Research\nSince its discovery, people have used LSD for self-exploration and spiritual growth. Therapists hope LSD will prove to be useful in reducing anxiety, treating depression, and relieving addictive tendencies. \n\n### 1950s and 1960s\nEarly research focused on the mystical experiences inspired by LSD or its use as a psychoanalytical tool to explore the unconscious. LSD allowed patients to observe their unconscious drives and motives while retaining part of their ego in therapeutic settings. Therapists believed LSD held promise in treating addiction, depression, obsessive-compulsive disorder, and end-of-life anxiety.\n\n### 1980s Swiss\nIn a backlash to the counterculture glorification of LSD in the 1960s and in response to [Timothy Leary's](https://pt.wikipedia.org/wiki/Timothy_Leary) campaign to normalize and mainstream acid's use, research was banned from the early 1970s to the mid-1980s. In 1988, the Swiss government granted permission to a group of therapists to research therapeutic uses of LSD. \n\n![Timothy Leary is the 1960s counter culture LSD icon](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_13_at_12_28_31_PM_25bfe440b6.png)\n\nParticipants in the study held different diagnoses and reasons for seeking treatment; these included eating disorders, addiction, psychosis, personality disorders, adjustment disorders, depression, anxiety, and sexual dysfunction. \n\nAll who received psychedelic dosing treatments were involved in group therapy and one-on-one therapy. About 90 percent of participants reported good or slight improvement on their therapy-related issues. The therapists observed no complications.\n\n### Recent LSD Studies\nFindings from more recent research on LSD include:\n- LSD has a success rate in treating alcoholism of 81 to 100 percent.\n- Two weeks after taking LSD, healthy individuals were more open and had a more positive outlook.\n- In combination with psychotherapy sessions, LSD reduced anxiety associated with life-threatening conditions such as cancer.\n- A large study of more than 130,000 people found no association between psychedelic use and mental health disorders, psychological distress, or suicidal thoughts.\n- LSD enhanced people's ability to feel empathy and their desire to be with other people.\n\n![Your brain on acid](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_13_at_12_31_42_PM_ad08b2913a.png)\n\n### Possible Risks of LSD\nSome people have reported bad acid trips where they experienced overwhelming feelings, heightened fear, a sense of losing their minds, and paranoia. However, there are no proven long-term adverse side effects of LSD use and no documented deaths in the United States. The risk of hurting oneself is very low, and LSD does not cause long-term physical dependency or addiction.\n\n### Legality of LSD\nLSD's classification as a [Schedule I drug](https://www.drugs.com/article/csa-schedule-1.html) by the U.S. government makes its manufacture, possession, distribution, and use illegal on a federal level. In light of the successes in the limited studies, researchers intend to request the drug be rescheduled to allow for treatment for end-of-life anxiety. \n\n### Get Your Medical Document & Purchase Medical Cannabis\n\nIt's easy to get your medical document with the online [Telehealth service HelloMD](https://hellomd.com/get-started). Register, pay, and receive an online medical consultation with a licensed practitioner and start purchasing medical cannabis today.\n","image":{"childImageSharp":{"fluid":{"base64":"data:image/png;base64,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","aspectRatio":1.5037593984962405,"src":"/static/e92db62ec544d1c2be7a1bf372f134d9/ee604/0328a893d48efb5c1ddb75fd9024af2d.png","srcSet":"/static/e92db62ec544d1c2be7a1bf372f134d9/69585/0328a893d48efb5c1ddb75fd9024af2d.png 200w,\n/static/e92db62ec544d1c2be7a1bf372f134d9/497c6/0328a893d48efb5c1ddb75fd9024af2d.png 400w,\n/static/e92db62ec544d1c2be7a1bf372f134d9/ee604/0328a893d48efb5c1ddb75fd9024af2d.png 800w,\n/static/e92db62ec544d1c2be7a1bf372f134d9/f3583/0328a893d48efb5c1ddb75fd9024af2d.png 1200w","srcWebp":"/static/e92db62ec544d1c2be7a1bf372f134d9/58556/0328a893d48efb5c1ddb75fd9024af2d.webp","srcSetWebp":"/static/e92db62ec544d1c2be7a1bf372f134d9/61e93/0328a893d48efb5c1ddb75fd9024af2d.webp 200w,\n/static/e92db62ec544d1c2be7a1bf372f134d9/1f5c5/0328a893d48efb5c1ddb75fd9024af2d.webp 400w,\n/static/e92db62ec544d1c2be7a1bf372f134d9/58556/0328a893d48efb5c1ddb75fd9024af2d.webp 800w,\n/static/e92db62ec544d1c2be7a1bf372f134d9/99238/0328a893d48efb5c1ddb75fd9024af2d.webp 1200w","sizes":"(max-width: 800px) 100vw, 800px"}}}}},{"node":{"id":"Article_3881-markdown","title":"What is Ketamine: Psychedelics 101","slug":"what-is-ketamine-psychedelics-101","content":"If you've ever had a general anesthetic, you may have heard of ketamine. The commercial use of ketamine began in the 1970s, and it's now commonly used for various clinical applications, including anesthesia, palliative care, and, most recently, for the [treatment of depression](https://www.webmd.com/depression/features/what-does-ketamine-do-your-brain). Ketamine is also well known for being a \"recreational\" drug on the party scene, and it has the potential for abuse. \n\n![Ketamine can help treat depression](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_11_at_10_30_42_AM_b6c432e9d6.png)\n\n### What Is Ketamine?\nKetamine's chemical makeup is similar to phencyclidine (PCP), nitrous oxide, and dextromethorphan (DXM). It's been widely used as an anesthetic for surgery in both humans and animals. Street names for ketamine are VitaminK, Super K, K, Green and Donkey Dust.\n\n### What are the Effects of Ketamine?\n[Ketamine provides](https://www.theguardian.com/science/sifting-the-evidence/2016/jul/14/what-are-the-effects-of-ketamine) complete sensory detachment and produces hallucinogenic-like effects. It is a dissociative drug with sedating effects and may cause numbness, memory loss, and unconsciousness while maintaining respiratory reflexes and adequate blood pressure. \n\n![Ketamine can produce hallucinations](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_11_at_10_31_47_AM_f008b0a2cb.png)\n\nKetamine has a psychedelic effect and may reduce overall body sensations. It produces an abrupt high that lasts for about one or two hours. The immediate effects of ketamine may include drowsiness, profuse sweating, an irregular heartbeat, confusion, nausea, numbness, and slurred speech. It may also create an overwhelming feeling of relaxation, and consumers may feel \"out of their bodies\" or a dream-like detachment. Ketamine can alter a person's sense of space and time and cause visual or auditory hallucinations. \n\nContinued ketamine use causes a slow heartbeat, elevated blood pressure, behavioral changes, and difficulty breathing. Heavy ketamine use results in urinary tract problems as it may thicken the bladder wall, causing pain during urination. Prolonged use may also cause agitation, panic attacks, and reduction of long-term and short-term memory.\n\n![Too much ketamine can cause disassociation from the body](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_11_at_10_33_09_AM_5b8ce660a3.png)\n\nToo much ketamine may cause immobility and a sense of going into \"k-hole,\" an intense feeling of separating from one's body. Withdrawal from prolonged ketamine abuse comes with numerous side effects such as depression, anxiety, lack of appetite, insomnia, and restlessness. It is possible to become addicted to ketamine, and with abuse, more may be needed to feel its effects.\n\nWhen used correctly, ketamine has numerous therapeutic benefits, including the following:\n\n### Treatment of Depression with Ketamine\n\nThe FDA recently approved ketamine for \"off-label\" consumption, and [clinics across the United States are using it to treat depression](https://hellomd.com/articles/ketamine-an-effective-treatment-for-depression). Recent studies indicate that up to 70% of patients treated with treatment-resistant depression improved when given an oral antidepressant with intranasal esketamine, a nasal spray derived from ketamine. \n\nIt's believed that [ketamine works for](https://www.medicalnewstoday.com/articles/302663) depression as it enhances the transmission of gamma-aminobutyric acid (GABA) and triggers glutamate production. In turn, this prompts the brain to create new neural connections. As new bonds form, patients can approach life with more positive associations and behaviors. Ketamine works quickly in treating depression and anxiety, whereas traditional antidepressants may take weeks to take effect, if at all. \n\n![Ketamine can ease depression](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_11_at_10_34_31_AM_4ac07b34a3.png)\n\nKetamine infusions for depression usually take effect within four to seventy-two hours, and patients may feel a lasting impact for 1-3 weeks. Anecdotal reports also indicate ketamine may be a potential treatment for obsessive-compulsive disorder, post-traumatic stress disorder (PTSD) and other neuropsychiatric disorders.\n\n### Chronic Pain Relief with Ketamine\nKetamine is frequently an effective treatment for chronic pain, neuropathic pain, and fibromyalgia. Low-dose ketamine infusions have had a beneficial effect on the central nervous system, effectively rebooting neurotransmitters within the brain. Patients may feel immediate and sustained relief from pain through a series of low-dose ketamine infusions. \n\n![Pain can be crippling](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_02_at_3_21_48_PM_0f3241603f.png)\n\nWhile surgical operations tend to be very painful, ketamine relieves acute pain significantly. When your nerves send those pain signals to the brain, ketamine cuts them off. You won't feel the excruciating pain after some surgical blades have cut through your body organs. Vietnam War soldiers used these psychedelics to relieve pain from injuries.\n\n### What are the Risks Associated With Ketamine?\nConsumption of ketamine within a clinical setting is considered relatively safe. Some patients may feel uncomfortable with the associated effects, such as feeling disassociated from the body or a sense of \"couch-lock.\"\n\nKetamine may cause an increase in blood pressure. People who have the following are not candidates for ketamine treatment:\n- glaucoma\n- brain lesions or tumors\n- brain swelling\n \nThere are several other conditions where ketamine treatments should be used with caution.\n\n### Is Ketamine Legal?\n\nThe [FDA has approved nasal-spray esketamine](https://www.fda.gov/news-events/press-announcements/fda-approves-new-nasal-spray-medication-treatment-resistant-depression-available-only-certified) for the treatment of depression. It's legal in specific states but each state has individual regulations on the administration of ketamine. Utah and Texas, for example, have legalized medicinal use of the drug, whereas other states such as California, Delaware, and Wyoming, among others, have placed ketamine as a Schedule III. \n\n### Ketamine Drug Interactions\nKetamine has seven significant [drug interactions](https://www.drugs.com/drug-interactions/ketamine.html) and two hundred and fifty-six moderate drug interactions. It is essential to check with a physician to determine how ketamine may interact with any medications currently in use.\n\n![Ketamine treatment within a clinic](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_11_at_10_36_46_AM_c4fda4a3fb.png)\n\n### Where Can I Legally Seek Ketamine Treatment?\nMore than 150 clinics in the US offer various forms of ketamine treatment. With the legalization of ketamine spray and infusions, new clinics continue to open. While it might not be easy to find a ketamine cline, there are many established providers in legalized states. When looking for a ketamine clinic, conduct due diligence, and check with your local healthcare provider.\n\n### Need Your Medical Marijuana Card?\n\n[HelloMD](https://hellomd.com/get-started/) can help you with online virtual medical consultation and get your medical card fast, easy and private.","image":{"childImageSharp":{"fluid":{"base64":"data:image/png;base64,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","aspectRatio":1.5037593984962405,"src":"/static/aa3f3edf5b95943ce60421cc579a24fd/ee604/ff45aa59c9cb8cdfae67ab0a5e89e8de.png","srcSet":"/static/aa3f3edf5b95943ce60421cc579a24fd/69585/ff45aa59c9cb8cdfae67ab0a5e89e8de.png 200w,\n/static/aa3f3edf5b95943ce60421cc579a24fd/497c6/ff45aa59c9cb8cdfae67ab0a5e89e8de.png 400w,\n/static/aa3f3edf5b95943ce60421cc579a24fd/ee604/ff45aa59c9cb8cdfae67ab0a5e89e8de.png 800w,\n/static/aa3f3edf5b95943ce60421cc579a24fd/f3583/ff45aa59c9cb8cdfae67ab0a5e89e8de.png 1200w","srcWebp":"/static/aa3f3edf5b95943ce60421cc579a24fd/58556/ff45aa59c9cb8cdfae67ab0a5e89e8de.webp","srcSetWebp":"/static/aa3f3edf5b95943ce60421cc579a24fd/61e93/ff45aa59c9cb8cdfae67ab0a5e89e8de.webp 200w,\n/static/aa3f3edf5b95943ce60421cc579a24fd/1f5c5/ff45aa59c9cb8cdfae67ab0a5e89e8de.webp 400w,\n/static/aa3f3edf5b95943ce60421cc579a24fd/58556/ff45aa59c9cb8cdfae67ab0a5e89e8de.webp 800w,\n/static/aa3f3edf5b95943ce60421cc579a24fd/99238/ff45aa59c9cb8cdfae67ab0a5e89e8de.webp 1200w","sizes":"(max-width: 800px) 100vw, 800px"}}}}},{"node":{"id":"Article_3880-markdown","title":"What is MDMA: Psychedelics 101","slug":"what-is-mdma-psychedelics-101","content":"### What is MDMA?\n\nMDMA is short for 3,4 methylenedioxymethamphetamine – a chemical compound that acts on the brain’s “feel good” neurotransmitters serotonin and, dopamine. It amplifies emotional connectedness, encourages people to be more open and trusting, and promotes a feeling of euphoria and relaxation. Although it gained a reputation as an illegal party drug, MDMA was originally intended to be used in clinical settings to treat certain conditions such as mental disorders, specific traumas, and phobias. \n\nRecently, the FDA designated MDMA-assisted therapy for PTSD a Breakthrough Therapy and MAPS’ Phase 3 clinical trial of [MDMA-assisted therapy](https://maps.org/mdma/ptsd/phase3/) demonstrated statistically significant improvement in PTSD symptoms after three sessions.\n\n![MDMA psychedelic-assisted therapy](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_10_at_5_37_08_PM_3b9942c403.png)\n\n\nSome common street names for MDMA include beans, ecstasy, molly, uppers, and X. Currently, there is renewed interest in using MDMA and other psychedelics to [treat various mental health and psychological issues](https://psychedelic.support/resources/psychedelics-as-therapeutics/). Critics of blanket criminalization of many drugs claim that governments have tended to overstate their negative effects while ignoring the potential benefits of their use.  \n\n### What are the Effects of MDMA?\n\nWithin an hour of ingesting MDMA, the brain will begin to increase the production of dopamine, serotonin, and norepinephrine. Consumers generally feel happier, and more connected to others for several hours following the initial dose. \n\n![MDMA makes people feel more connected](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_10_at_5_36_10_PM_1849df97c0.png)\n\nMDMA became a popular form of recreation at music festivals and raves due to its effects on perception, especially related to color and sound. Increased physical activity while under its influence can also lead to higher body temperatures and a warm feeling. \n\n### What are the Therapeutic Benefits of MDMA?\n\nLike all psychedelics, MDMA makes temporary changes to brain activity; however, if the brain is not functioning optimally due to some disorder, psychedelics may help a person’s brain work 'normally'. \n\n![Cannabis can ease anxiety](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_02_at_3_20_06_PM_624826d60d.png)\n\nDepression is caused by several factors, such as stress tied to specific events, an inability of the brain to regulate moods properly, chemical imbalances, and more. The Multidisciplinary Association for Psychedelic Studies (MAPS) is [sponsoring clinical trials](https://maps.org/mdma/mdma-resources/treatment-manual-mdma-assisted-psychotherapy-for-ptsd/) to explore the potential risks and benefits of MDMA-assisted therapy in chronic posttraumatic stress disorder (PTSD) participants.\n\nEarly studies sponsored by MAPS reveal that overall, 83 percent of participants no longer met the criteria for PTSD after using MDMA. That kind of success, say MAPS researchers, is reason to push for final studies aimed at getting full approval to market MDMA for PTSD treatment by 2021.\n\nAnother study from 2016 found that multiple patients experienced a significant reduction or remission in their chronic depression after just a week of taking psychedelics. In addition to [treating depression and PTSD](https://hellomd.com/articles/mdma-assisted-therapy-a-successful-treatment-for-ptsd), MDMA has also helped addicts who take drugs such as heroin kick their addictions successfully. Researchers are optimistic that those who have addictions to cocaine and other drugs will experience similar benefits.\n\n### What Risks Associated with MDMA?\n\nIllicit MDMA that is improperly prepared or mixed with other chemicals can prove to be fatal or cause other health problems. Side effects can include high blood pressure, panic attacks, and seizures. Unadulterated MDMA is administered in clinical trial settings under supervision. If you decide to take MDMA outside of a setting such as this, it is highly recommended to [self-test your MDMA for purity](https://elevationchemicals.com/?gclid=Cj0KCQiAjJOQBhCkARIsAEKMtO0RqZ_usBC-Wx9HJkvrskfKfYo6nWcebhImg_xTo_wPfXIiIAVeUCUaAt5xEALw_wcB) with a testing kit - it could save your life.\n\n### Is MDMA Legal? \n\n![MDMA is a Schedule1 drug](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_10_at_5_34_37_PM_7d76171632.png)\n\nIn the United States, MDMA is classified as a [Schedule 1 substance](https://www.drugs.com/article/csa-schedule-1.html). If the FDA approves MDMA, it may become legal in clinical settings and administered by mental healthcare providers trained in psychedelic-assisted therapy.\n\nSome countries in Europe, like the Czech Republic, Spain, and Italy, have decriminalized possession of small amounts of the drug for recreational use. However, it is illegal to distribute and sell MDMA.\n\n### What Drug Interactions May Occur with MDMA?\n\n![Alcohol can have a negative interaction with MDMA](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_10_at_5_32_56_PM_885e00875e.png)\n\nThe effects of taking MDMA with other drugs − including over-the-counter or prescribed medications − can be unpredictable and dangerous. This includes [alcohol, cocaine, anti-depressants, and others](https://adf.org.au/drug-facts/mdma/#:~:text=Mixing%20MDMA%20with%20other%20drugs&text=MDMA%20%2B%20alcohol%3A%20increased%20risk%20of,consequently%20drinking%20too%20much%20water.&text=MDMA%20%2B%20ice%2C%20speed%20or%20cocaine,functioning%20due%20to%20dopamine%20depletion.). It is best to refrain from using other drugs or talk to a professional before mixing MDMA with any prescription medications, as these interaction effects can become dangerous. \n\n### Can I Legally Seek Treatment with MDMA?\n\n At this time, anyone interested in MDMA psychedelic-assisted therapy will need to join a study or research program. Clinical Trials are currently being conducted with MDMA. Organizations such as [Healthmatch](https://healthmatch.io/?utm_source=search&utm_medium=paid&utm_campaign=General_Australia&utm_content=131002038924&utm_term=&gclid=Cj0KCQiAjJOQBhCkARIsAEKMtO2lMi-_CakvpfwSbI3djlLPgOIiiQSmSPTt8UHtH1MvqleK0HyE4tMaAkkOEALw_wcB) can help you find an appropriate upcoming psychedelic clinical trial.\n\n### Get Your Medical Document & Purchase Medical Cannabis\n\n![You need to get certified by a doctor to get your medical marijuana card](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2022_02_04_at_4_09_20_PM_d316f42934.png)\n\nIt's easy to get your medical document with the online [Telehealth service HelloMD](https://hellomd.com/get-started). Register, pay, and receive an online medical consultation with a licensed practitioner and start purchasing medical cannabis today.","image":{"childImageSharp":{"fluid":{"base64":"data:image/png;base64,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","aspectRatio":1.5037593984962405,"src":"/static/c299948617e988d52478372c31e3332e/ee604/643fd3837b8c32bcff33ae81e409bb99.png","srcSet":"/static/c299948617e988d52478372c31e3332e/69585/643fd3837b8c32bcff33ae81e409bb99.png 200w,\n/static/c299948617e988d52478372c31e3332e/497c6/643fd3837b8c32bcff33ae81e409bb99.png 400w,\n/static/c299948617e988d52478372c31e3332e/ee604/643fd3837b8c32bcff33ae81e409bb99.png 800w,\n/static/c299948617e988d52478372c31e3332e/f3583/643fd3837b8c32bcff33ae81e409bb99.png 1200w","srcWebp":"/static/c299948617e988d52478372c31e3332e/58556/643fd3837b8c32bcff33ae81e409bb99.webp","srcSetWebp":"/static/c299948617e988d52478372c31e3332e/61e93/643fd3837b8c32bcff33ae81e409bb99.webp 200w,\n/static/c299948617e988d52478372c31e3332e/1f5c5/643fd3837b8c32bcff33ae81e409bb99.webp 400w,\n/static/c299948617e988d52478372c31e3332e/58556/643fd3837b8c32bcff33ae81e409bb99.webp 800w,\n/static/c299948617e988d52478372c31e3332e/99238/643fd3837b8c32bcff33ae81e409bb99.webp 1200w","sizes":"(max-width: 800px) 100vw, 800px"}}}}},{"node":{"id":"Article_3657-markdown","title":"Need Help with a Bad Psychedelic Trip? Call the Fireside Project for Emotional Peer Support.","slug":"need-help-with-a-bad-psychedelic-trip-call-the-fireside-project-for-emotional-peer-support","content":"Have you ever eaten too much of an marijuana-infused brownie and had a really bad trip? Many of us have had one of these unfortunate experiences; we eat the whole edible, leading to a 6 hour long paranoid-anxious freakout. Minutes can feel like hours, your eyes are wide as saucers, and your mouth feels like paste as you try to rock yourself to sleep in a dark room. \n\n### Having a Bad Trip is Bad News\n\nMaureen Dowd, the well-known NY Times columnist, wrote of her experience with a pot-laced brownie while visiting Colorado during the initial hay day of marijuana legalization. She took a nibble of the brownie and then a bit more, and before she knew it, she was alone and stoned; incapacitated in her hotel room. She wrote about her experience in [\"Don't Harsh Our Mellow, Dude\"](https://www.nytimes.com/2014/06/04/opinion/dowd-dont-harsh-our-mellow-dude.html?_r=0), in The New York Times (to much acclaim). After Dowd finished her brownie, the story goes like this:\n\n\"I lay curled up in a hallucinatory state for the next eight hours. I was thirsty but couldn't move to get water. Or even turn off the lights. I was panting and paranoid, sure that when the room-service waiter knocked and I didn't answer, he'd call the police and have me arrested for being unable to handle my candy.\"\n\nLet's face it; whether you consume cannabis, [magic mushrooms (psilocybin)](https://hellomd.com/articles/microdosing-101:-cannabis-psilocybin-and-lsd), or any other hallucinogenic drug, there's a possibility of things going sideways. Just some of the (many) ways things may go pear-shaped:\n- Without proper education, you can consume too much and become overwhelmed which may result in a bad trip\n- You may be in the wrong location (setting)  with the wrong people (set) and begin to feel anxious or paranoid\n- Maybe you've had a great experience but feel isolated afterward and need someone to talk to\n\nThe bottom line, many psychedelic/psychotropic experiences go off the rails when you feel alone, disconnected, or fearful. There is good news. [Fireside Project](https://firesideproject.org/), a new psychedelic peer support line, is out to change all of that. \n\n### What is a Psychedelic Peer Support Line?\n\nFireside's mission is to \"help people minimize the risks and fulfill the potential of their psychedelic experiences\". Through a free, emotional peer support line, you are one phone call (or text) away from receiving support before and during a trip (whether it be \"bad\" or \"good\"). You may also want to receive integration support after having a psychedelic/psychotropic experience. \n\nFireside's Founder, (a former lawyer turned psychedelic advocate), Joshua White, says \"We started Fireside Project because we want to make sure that no one ever has to feel alone with a psychedelic experience. We see Fireside Project as a glowing mycelial web of connection and understanding that will start in the United States and eventually embrace the whole world.\"\n\n![Screen Shot 2021-05-12 at 9.48.37 AM.png](https://hellomd-cms.s3.us-west-2.amazonaws.com/Screen_Shot_2021_05_12_at_9_48_37_AM_1e60222403.png)\n\nFireside Project aims to provide compassionate and culturally responsible peer support while helping to educate the public. Through providing free and confidential support to those in need, they create a culture of belonging through compassionate, non-judgement, and transparent communication.\n\n### Is Cannabis a Psychedelic?\n\nWell, technically, cannabis is not a psychedelic. Psychedelic drugs are typically classified as those that produce hallucinations or an apparent expansion of consciousness. Marijuana is a psychotropic, meaning it has psychoactive qualities due to its THC content. \n\nHowever, many psychiatrists and mental health professionals believe cannabis effects can be psychedelic in nature. Increasingly, as the THC content goes up in cannabis and people have more access, there is a higher likelihood that people may need support before, during, or after a cannabis experience. For many people, the psychoactive element of THC,  can also be [extremely disorienting](https://hellomd.com/articles/the-pros-and-cons-of-psychoactive-thc). Patients using THC may find themselves feeling confused or unable to think clearly. \n\nJoshua agrees with this saying, \"Fireside Project welcomes people who are having psychedelic experiences of all kinds. Cannabis experiences can definitely be psychedelic, and we are honored to provide support for those types of experiences as well.\"\n\n### What Happens If You Call Fireside?\n\nWell, it depends on who you are and why you're calling. Fireside was created to helps people tripping in the moment, and people wanting to talk about past trips, aka 'integration' talk. That said, you don't need to be having a bad trip, maybe you just need some emotional support from someone creating a 'safe space'. \n\nWhen you call Fireside it is completely confidential, you don't even need to tell them your name. The person on the other side of the line is for emotional support only, they are not doctors or therapists. Rather, think about that person like you would a trusted friend. Fireside is not to be used in lieu of medical care and is not a medical screening service. So, if you believe you are having a medical emergency or are suicidal, call your local crisis hotline or 911.\n\nWhen appropriate Fireside may refer you to sources of information, but it's up to you whether you rely on that information. Fireside is available only in the United States at the moment but hopes to expand service to other countries. If you like your Fireside conversation, you can call back as many times as you like, but you will most likely speak to different people.\n\n### The Future of the Fireside Project\n\nFireside Project launched in April of 2021 and has quickly entered into a research partnership with UCSF. The hope is to learn from the psychedelic experiences of community members, then share the lessons learned.\n\nThe study with UCSF researchers explores whether the support line is an effective risk reduction tool. People who use the peer support line are sent an anonymous survey 24-hours after the initial call. So far, callers have indicated that Fireside has helped them overcome various challenges.\n\nFireside is available Thursday to Sunday, from 3:00 p.m. to 3:00 a.m. PST and Monday from 3:00 p.m. to 7:00 p.m. PST. The line will eventually be open 24 hours a day, seven days a week. If you are interested in supporting Fireside with a [tax free donation](https://firesideproject.org/donate), they welcome your support.\n\n**Call Fireside Project: 623-473-7433 OR 6-2FIRESIDE**\n\n","image":{"childImageSharp":{"fluid":{"base64":"data:image/png;base64,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","aspectRatio":1.5625,"src":"/static/37836d7f28227caf37ef5bc34559671f/ee604/2fd50a8551e4b84321792eeccf67710d.png","srcSet":"/static/37836d7f28227caf37ef5bc34559671f/69585/2fd50a8551e4b84321792eeccf67710d.png 200w,\n/static/37836d7f28227caf37ef5bc34559671f/497c6/2fd50a8551e4b84321792eeccf67710d.png 400w,\n/static/37836d7f28227caf37ef5bc34559671f/ee604/2fd50a8551e4b84321792eeccf67710d.png 800w,\n/static/37836d7f28227caf37ef5bc34559671f/f3583/2fd50a8551e4b84321792eeccf67710d.png 1200w","srcWebp":"/static/37836d7f28227caf37ef5bc34559671f/58556/2fd50a8551e4b84321792eeccf67710d.webp","srcSetWebp":"/static/37836d7f28227caf37ef5bc34559671f/61e93/2fd50a8551e4b84321792eeccf67710d.webp 200w,\n/static/37836d7f28227caf37ef5bc34559671f/1f5c5/2fd50a8551e4b84321792eeccf67710d.webp 400w,\n/static/37836d7f28227caf37ef5bc34559671f/58556/2fd50a8551e4b84321792eeccf67710d.webp 800w,\n/static/37836d7f28227caf37ef5bc34559671f/99238/2fd50a8551e4b84321792eeccf67710d.webp 1200w","sizes":"(max-width: 800px) 100vw, 800px"}}}}},{"node":{"id":"Article_3641-markdown","title":"A HelloMD Interview: Psychedelics Expert Dr. Evan Wood, MD, PhD of Numinus Wellness on Mental Health & Addiction","slug":"a-hellomd-interview-psychedelics-expert-dr-evan-wood-md-phd-of-numinus-wellness-on-mental-health-and-addiction","content":"Dr. Evan Wood, MD, PhD is Chief Medical Officer at Numinus Wellness, a psychedelics company out of Vancouver, BC. Numinus is on the cutting edge of mental healthcare, specializing in psychedelic-assisted psychotherapy with novel psychedelic compounds.\n\nDr. Wood has a passion for changing policy, often by putting research into practice. Early in his career, his research contributed to the international guidelines for treating HIV infection among persons who use drugs. His later work contributed to the legalization of adult cannabis use in Canada and establishing clinical therapeutic guidelines for a range of substance abuse disorders.\n\nOver the last 20 years, Dr. Wood has delved deeply into the science and research around substance use and addiction. His lab was a participating site in the maps phase three clinical trial of MDMA-assisted psychotherapy for post-traumatic stress disorder.\n\nHe is recognized for his work in improving clinical systems through  research and policy leadership, particularly within the field of addiction and mental health. \n\nDr. Wood is passionate about his work in forwarding psychedelics' clinical use for various intractable health conditions. As Chief Medical Officer of Numinus Wellness he is breaking ground for safe, legal access to psychedelic medicine for conditions including depression, PTSD & substance use disorders.\n\nBelow is HelloMD's interview with Dr. Wood discussing the future of clinical-assisted psychotherapy and treatment with psychedelics.\n\n**Question: Dr. Wood, please tell me how you perceive the current mental healthcare system, where it succeeds, and where it fails?**\n\n**Answer**:  I actually view the entire field of mental health and addiction with a great deal of consternation and skepticism. Currently, I think that the widely made interventions in the mental health and addiction world are often not evidence-based.\n\n I believe we pathologize a lot of things that are actually, in many respects, part of the human condition - such as anxiety and depression. It isn't that we shouldn't take them seriously. \n\nHowever, things like anxiety and depression are things that we need to grapple with from the perspective that it is part of the human condition. I do not believe we should pathologize people and tell them that they have a disease, necessarily. \n\nI believe the prescription medications that are commonly employed with mental health conditions otentimes have dubious benefits. For some patients the benefits are genuine, but for many patients there aren't any noticeable benefits. We have this notion of a mental health system that involves getting a prescription and taking a pill, as if that's going to be the solution.\n\nOften patients don't like taking these medications, as they experience negative side effects, whether it's weight gain or erectile dysfunction, or even more serious side effects, like increasing the risk of suicide. Unfortunately, I don't think we have a functioning mental health and addiction healthcare system in our society. \n\nInstead of offering a medication, perhaps we should look at changing a person's environment. That might be a better start. If we think that by taking a pill every day we're going to solve society's mental health challenges, I think that's wrong. \n\nAnyone who says that, really needs to check in with their own ethics. The reality is, we need a totally different approach to wellness and recovery with early intervention. Going to see your primary care physician who writes you a prescription for anti depressant after 10 minute assessment; is not going to help us become a healthier society. So, we need a total rethink around that\n\n**Question: What success have you had in reforming the mental and addiction healthcare system?**\n\n**Answer:** There are some bright spots and areas of success and accomplishments that I am proud of. I was involved in creating North America's largest addiction medicine training program at the University of British Columbia. During this time, I helped train and mentor junior trainees within the fields. \n\nI've had accomplishments such as being the founding principal investigator of the first supervised injecting facility in North America in terms of addiction. Here, people can get pre-obtained street drugs and use them under healthcare practitioners' supervision to avoid overdose and help connect them with addiction treatment.\n\nAnother area where I've worked with others towards success is in authoring national therapeutic guidelines for the treatment of different substance use disorders.  I've got a wonderful group of colleagues here in British Columbia, and everything that I just shared has been part of a team effort. Furthermore, I'm proud of what my colleagues have done by going the extra mile to try and create a more functioning system of care for people with mental health and addiction. \n\n**Question: Besides getting involved in psychedelic research, you also were active within federal cannabis legalization in Canada?**\n\n**Answer:** Historically, there's been a massive illicit cannabis industry driven by local interest in (consuming) cannabis and the huge illicit export market to the the United States. Pre-legalization, the illegal outdoor and indoor cannabis industry boomed. In reality, this trade supported people and families; many people had basement cannabis grows which paid their bills and paid off their mortgages. However, there was a dark side to all of this.\n\nThis was an illegal economy, and we had all sorts of problems and continue to, because illegal drugs allowed organized crime and gang violence to flourish. There began to be a lot of intelligence sharing between the US and Canada as it went from cannabis to cocaine, and guns coming into the country due to the illicit trade.\n\nDue to the escalating situation, I helped to found a coalition called Stop The Violence BC, where we began to change the narrative in British Columbia. The fact the government made cannabis illegal was making the situation worse, not better. As crime worsened around the illegal cannabis trade, there was a tipping point in public opinion in Canada.\n\nOur group worked with the junior liberal party of British Columbia that ultimately took a motion to the national convention where Justin Trudeau, our current Premier, committed to legalizing and regulating the adult use of cannabis for recreational use in Canada. This was a foundation for the legalization of cannabis in Canada and helped to build the legal framework in which we work today.\n\n**Question: As Chief Medical Officer of Numinus, what do you see today and what do you hope to achieve for the future of psychedelics?**\n\n**Answer:** Our lab is a participating site in Phase three clinical trial of MDMA for post-traumatic stress disorder, which MAPS has now helped yo complete. One particular area of interest for me is how this might have a positive impact the world of addiction. \n\nFor instance, one psychedelics called ibogaine, has shown great success in treating addiction. Traditionally, it's been legal in Canada but illegal in the United States. There's a whole industry of people offering ibogaine treatment to British Columbia, but it has some toxic effects, so I'm not a big advocate for it. \n\nOne reason is that ibogaine can cause a cardiac arrhythmia and can be quite dangerous for some people. But, I've certainly had patients who were in the throes of addiction and came back into my office, and I'd be like, \"Whoa, you look amazing. What happened?\" And then they would say, \"Oh, I went and did ibogaine.\" So, that is something, and I believe we have yet to see the full potential psychedelics have in treating addiction and mental health conditions.\n\nAs a result, I developed an interest in understanding psychedelics as a new approach to medicine- a new paradigm. I'm an avid consumer of the literature. With new and different studies being published by institutions such as Johns Hopkins, you can see the results of research with psilocybin for addiction and mental health and the positive outcomes being experienced.\n\nWhen it comes to addiction, the rational mind often does not allow for someone to stop using a substance. It's like the reptilian brain takes over and goes haywire with addiction, and then there is the reward pathway with dopamine that induces people to take more of a substance.\n\n I think psychedelics offer the opportunity to bring together that thoughtful brain with that reptilian brain to create radical change. It's also a total paradigm shift because you're not talking about a daily medication, take a pill and you're immediately better. We're talking about a strategy to put somebody through a psychotherapeutic intervention with psychedelics and, ultimately, a possible cure.\n\nPsychedelic intervention, in both the mental and addiction space, is extremely promising. There's more research to be done, but it looks extremely promising right now. So, I am super excited to be part of the different groups that are exploring these interventions. It shows such promise, and this may be a building block towards a much more evidence-based approach to mental health care.\n\n**Question: Today, what is Numinus doing within the psychedelics space and how does it differ from other players within the space at this point?**\n\n**Answer:** Numinus has excellence among the leadership team. In some instances, our team has lived through the psychedelic experience and has felt first hand the impact it may have on one's life. \n\nOur CEO, Peyton Nyquist has been very public about his own challenges with PTSD and how he was in and out of hospital until he found psychedelic-assisted psychotherapy. \n\nIf you saw him today, he's the absolute picture of health. Thus, he carries that motivation as someone who was in a life-threatening situation and found something, psychedelics, which helped him. People who live through these experiences want to create real change, and often do. \n\nOur lab was also the first to be federally approved by Health Canada to grow psilocybin mushrooms. We are very active in doing extractions and developing products, and understanding these mushrooms on a deeper level through science. There's psilocybin, but there are also other psychoactive molecules of importance. There's lots to be learned and done in this space. We have a long ten-year history as a lab, so it is a very experienced team with great ability.\n\nThere's also the clinical side of Numinus. We are interested delivering excellence in service in regards to psychedelic clinically-assisted psychotherapy, that is evidence-based. We also take the experience from historical traditions (indigenous cultures), and learnings from the underground psychedelic community over the last many decades. Of course, we also look at the best practices from the institutions doing the serious research and clinical trials, which have brought us to where we are today.\n\n**Question: What about ketamine? It is one psychedelic that is currently legal in much of North America. What are your thoughts?**\n\n**Answer:** We're also very interested in ketamine and ketamine-assisted psychotherapy because it's extremely promising. If you look at being a full-service psychedelic clinic network, ketamine can allow us to treat individuals more or less today. \n\nIt could be anxiety or depression or post-traumatic stress disorder. Within a clinical setting, we can have very highly skilled therapists and health professionals who can make an appropriate diagnosis. \n\nTherapists can tailor a  treatment, which may or may not involve psychedelics, whether that be ketamine today or psilocybin in the near future. This model may involve other mental health and addiction services with a curative intent. We aim to help people, by treating a person holistically, including mindfulness practices. This may also involve psychedelic-assisted psychotherapy. Ultimately, we are changing the way we look at mental health and addiction within society, to help create better outcomes than what we experience today.\n\n[Watch Dr. Evan Wood](https://www.facebook.com/NuminusInc/videos/362513918349866) talking about psychedelics and the therapeutic potential.\n","image":{"childImageSharp":{"fluid":{"base64":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABQAAAANCAYAAACpUE5eAAAACXBIWXMAABYlAAAWJQFJUiTwAAADh0lEQVQ4yx2T60/bBRSG+6f4JywuLhoXNXOTZQM2QVpaSum95dJSbKFteqFlXAq90jstbWnp1jIKowx0WzBotpllISYEdVm8xKGyRZPpB2c0fHj8yUnOx/PmPed5j+jsW6cZs40wG4oiEXfyYXsL5UqZSiFLrZwnHpmmsVrjr1f/8urvf3j+20uefP+MG40mT3/8hb39bwmkcthmokRjIUQXL7zLxLiLUDSOUimn62oL1coSG40bNIV22EwMGVUUC4v8evSc/+v4+JgfDl/w+OA7lmoNJuczRHNFKsU0IrVCTDAwRSKdQ69TIhO3Uq/XubfVxOe0MmZQ4tXJULedwzqgYff+lzz66oBgJMrg8Ai9vT2YTP2YzQOo+qSIVL1dTE9NkMoWMOgVSCVtrDRu4baPELYo2W8ssr+S45v1Ep+VM/jdTu7u7DITTTEZTuKdDhONhBh3OzAP9yNSyDoY97pYKFQEhwr6jUrq67fp7mglOyLnQcbPXjXB12slnmxeZ2HOz8s//qS2cYfVTz7n5uY9GvUqxWycueA1RHLJFSyC3XyhjFYjx6jvpbnzEFl3F/aeNuKOIfK+UVJOE+WAl+iEWwDzO9W1LUFwl9WNTRq1JQqZeQFKAJFGWPnM6VOEY0l02p6T3rj7ELtBxWDHBZwaGTMmNUn7EDNmHbkpD4c/H1FYrrGwdJ3a6hrFhTjLhTSpdARRj7idt998g7nwPHqtDJm0naX6baY1EjLDMppTFvIjfexmAjyuxPliMcizwyM27gjutnfY3Nqmkk+SzyRIpsKIBrRypMJ6c+EYOk03LefOYDBbmZvw4el+nxWPXhDvZNlrZTfl5/7K4klclm/eIhyaY7tWophLEgjMEEtEEZkEsgaD9kRQ2dvBpYvvIFFoMFlHsUpamFK1ktDLqTs/purW8+jTdZ7+9IJ0NsfooIpmMUE2nSAozMeSCUT9aiFjagWzwQh98o+4fPkDzGNuZudTGLrbUZ9/nYRJTu2anfSolpVSjgd7B8RTSRzDejZLCRKxIE63D+/kBCJdnwSFogefz0uf7CpSqRjXtYCQsTgGlZKWU6+hunIemwAnbTdSzafJliqM2oxYjFKyQf9J7MRyJTaHXbih8AmWYYHg5DiWIR0ul4OZUISz77Wg7Hcx7fJg675E1mVhPeAg4PPhn40waJTjddtIZTKMe1y0d0rw+zz8B6JAn51EQoqnAAAAAElFTkSuQmCC","aspectRatio":1.5267175572519085,"src":"/static/a32e0c9bfbdd3de38b403ab8d7527822/ee604/ddbaeb4c42c4f0f5e414924363f25e8c.png","srcSet":"/static/a32e0c9bfbdd3de38b403ab8d7527822/69585/ddbaeb4c42c4f0f5e414924363f25e8c.png 200w,\n/static/a32e0c9bfbdd3de38b403ab8d7527822/497c6/ddbaeb4c42c4f0f5e414924363f25e8c.png 400w,\n/static/a32e0c9bfbdd3de38b403ab8d7527822/ee604/ddbaeb4c42c4f0f5e414924363f25e8c.png 800w,\n/static/a32e0c9bfbdd3de38b403ab8d7527822/f3583/ddbaeb4c42c4f0f5e414924363f25e8c.png 1200w,\n/static/a32e0c9bfbdd3de38b403ab8d7527822/a39f1/ddbaeb4c42c4f0f5e414924363f25e8c.png 1406w","srcWebp":"/static/a32e0c9bfbdd3de38b403ab8d7527822/58556/ddbaeb4c42c4f0f5e414924363f25e8c.webp","srcSetWebp":"/static/a32e0c9bfbdd3de38b403ab8d7527822/61e93/ddbaeb4c42c4f0f5e414924363f25e8c.webp 200w,\n/static/a32e0c9bfbdd3de38b403ab8d7527822/1f5c5/ddbaeb4c42c4f0f5e414924363f25e8c.webp 400w,\n/static/a32e0c9bfbdd3de38b403ab8d7527822/58556/ddbaeb4c42c4f0f5e414924363f25e8c.webp 800w,\n/static/a32e0c9bfbdd3de38b403ab8d7527822/99238/ddbaeb4c42c4f0f5e414924363f25e8c.webp 1200w,\n/static/a32e0c9bfbdd3de38b403ab8d7527822/8adbf/ddbaeb4c42c4f0f5e414924363f25e8c.webp 1406w","sizes":"(max-width: 800px) 100vw, 800px"}}}}}]}},"pageContext":{"limit":12,"skip":0,"numPages":3,"currentPage":1,"id":5666,"name":"Psychedelics","slug":"psychedelics","country":"US"}},"staticQueryHashes":["3949754563","4179947113","4202924991"]}