{"componentChunkName":"component---common-build-tags-template-js","path":"/tag/seizures/","result":{"data":{"allArticle":{"edges":[{"node":{"id":"Article_3080-markdown","title":"Meet HelloMD’s New Chief Medical Officer Dr. Patricia Frye","slug":"meet-hellomds-new-chief-medical-officer-dr-patricia-frye","content":"Dr. Patricia Frye has been a practicing cannabis physician for four years—in fact, she was the first doctor HelloMD hired to consult with patients online. Today, she’s HelloMD’s chief medical officer and a regular on our Ask a Doctor livestream series, where she answers audience questions about cannabis every week. \n\nBesides being a part of the HelloMD family, Dr. Frye runs her own thriving cannabis practice in Maryland. And on top of that, she’s recently released a book, “[The Medical Marijuana Guide](https://www.amazon.com/dp/B07KCMNCFQ/ref=dp-kindle-redirect?_encoding=UTF8&btkr=1),” which draws on her clinical experiences in cannabis medicine. \n\nFOLLOW US ON [FACEBOOK](https://www.facebook.com/pg/hellomdcompany/posts/) & [INSTAGRAM](https://www.instagram.com/hellomd_us/?utm_medium=copy_link/)\n\nWe caught up with Dr. Frye one afternoon to learn more about her background, practice and how she translated her work recommending cannabis into her first book. \n\n### Tell me a little bit about your background. Where did you go to medical school and what kind of medicine did you practice before you got into cannabis? \n\nI went to medical school at University of Maryland, and I graduated from there and then stayed and did a pediatric residency; I'm board certified in pediatrics. And when I finished at Maryland, I moved to Texas, and then I went to Baylor where I studied anesthesiology. \n\nMy goal was to do pediatric intensive care or acute care. But in Houston you really couldn't do just pediatrics, so we ended up moving to southern California. And at that time, I had a young son who was having some difficulties.\n\nSo that type of scheduling really didn't work out, and I ended up back in general pediatrics. And I did that for a number of years, [working with] school and behavior problems as well as taking care of sick kids. And when I was almost retired, I came back to Virginia. \n\nThen in 2015, I got a job with HelloMD, and that was actually my first introduction to cannabis. I never really had any involvement with it—never even thought about it really—the whole time I was in California. So, it was after I got back to the east coast that I was introduced to it.\n\n### And what surprised you most about cannabis once you started to familiarize yourself with the plant? \n\nWhat surprised me the most is that you can use it and not be impaired. I didn't realize that you could use it that way—I learned that from my elderly California patients. And then it surprised me as to how effective it was, and how helpful it was for a lot of patients.\n\n### Did you have any experience in alternative medicine before working with cannabis? \n\nWell, I'm an allopath—I liked doing procedures and using medication and intensive care. I wasn't really on the alternative path, because I worked for Kaiser [Permanente], and so there wasn't really a lot of opportunities to kind of dabble with that.\n\nBut during the time that I was at Kaiser, I saw a lot of school and behavior problems, and I ended up being one of three pediatricians who saw the autistic patients in Orange County. So that was kind of a soft introduction to some alternative things.\n\nAt the time, people were kind of experimenting with gastrin, which is a digestive enzyme, for autism. And I wasn't really on the big alternative bandwagon, but there was one family who had a son who was nonverbal—very limited, a lot of restrictive behaviors—and they wanted to try the gastrin. \n\nSo, I talked with my medical director and first, my department chairman, I got the OK to use it. I gave him about two or three infusions, and low and behold, it really changed a lot for him. He started talking; he started eating things; and so, I saw a big dramatic improvement. \n\nHis response was so dramatic and so impressive that when I was introduced to cannabis, I think because of that experience, I was a little more open-minded to it than I might've been otherwise.\n\n### Given that you come from an allopathic background, what do your previous colleagues say about the work that you do now with cannabis? \n\nI don't see any of my old colleagues from California much, but I do interact with some pediatric colleagues here locally that I trained with in Baltimore. One of them sends me patients and the other one became a patient. I have other classmates who are medical directors of big internal medicine practices, and I've gone and talked [at their practices], and they send me patients.\n\n### So, it seems like the kind of work you do in the cannabis space is pretty well accepted. Can you talk about the work do you with cannabis outside of HelloMD? \n\nI've lectured quite a bit in the area. I've spoken at two of the medical schools and about three or four hospitals in the area. I do continuing medical education for nurse practitioners and for physicians on cannabis.\n\nBy doing this, I've developed quite a referral base from other doctors. I get a lot of referrals from mental health providers, from psychiatrists. There are about six psychiatrists that send patients to me. \n\nI get referrals from Children's National Medical Center, from their pediatric neurologist. Now that Epidiolex is available, I don't get as many, but for a while I got a steady stream of neurology and some oncology patients. I've done hospital visits in the area for children with cancer, where they're not doing well, and we get them on cannabis at least to try to help them feel better.\n\nI get a good number of patients from Johns Hopkins, from the pediatric gastroenterology [division]; I see a lot of Crohn's and ulcerative colitis [patients]. So, I have a fairly good reputation here locally.\n\nI write out treatment plans for these patients, and what I think they should use and what things to avoid or what to try next. It's turned into a very rewarding practice. \n\n### A lot of your book is based on your clinical experience with cannabis. Have you noticed a pattern in the types of conditions that tend to respond best to cannabis? What about conditions or patients that respond the worst?\n\nDefinitely mental health and GI [patients] respond very well. I see a lot of [people with] inflammatory pain, a lot of neuropathic pain. \n\nThe patients I see are generally fairly sick or nothing is working for them or they've experienced a lot of adverse effects from pharmaceuticals. I see a few trickling in that are mainly functional medicine type patients, where nobody can figure out what's wrong. They usually have a lot of pain. I think some of those are autoimmune. I've seen some really good results from autoimmune patients. \n\nThese patients are generally fairly sick or fairly debilitated. And so, for most patients, I do see pretty decent improvement. About 40% are chronic pain. Most of the patients I see are cannabis naive. \n\nI find that some of the patients who do the worst are the older Caucasian women, and they tend to be small. For some reason they say they’re very excruciatingly sensitive to THC—those are the ones who’ve been the hardest to get comfortable, because it seems like they'll just take one drop [of THC] and they're on the floor. \n\nBut the mental health patients seem to respond really well. Chronic pain in general tends to respond really well. I have a good response with autism. Those patients seem to improve, and I would say the seizures are the ones that are kind of hit or miss. Sometimes I'll switch them from CBD to THCA or microdose with THC. \n\nAutism patients tend to do well with CBD. Sometimes we'll add a little bit of THC or THCA and that sometimes can help. Now they're doing studies with CBDV—but it's not really available yet. \n\nI have a fair number of cancer patients who are using cannabis either as an adjunct to their conventional therapy or conventional therapy isn’t helping. I'm not overly impressed with it, but I do have a couple of patients where their tumors have resolved. But considering all of the patients that I've seen, cannabis isn’t as effective as I would hope it would be. Some of that also has to do with product availability in this area. \n\n### Let’s take a few minutes to talk about your book. Who did you have in mind as the audience when you were writing a guide on cannabis? \n\nMy goal was to make it simple enough that most people could understand it, but to have enough interesting science in it so that other providers could read it, understand it, and then maybe open their minds to using cannabis for their patients.\n\n### How's your book different from some of the other cannabis books that are out there?\n\nMost of the other cannabis books are written by nonclinical people, people who aren’t doctors. There are few out there—[Dr.] Bonnie Goldstein's book came out right after I had signed a contract for this book—but most of the other books are mostly written by scientists like [Roger] Pertwee and [Ethan] Russo.\n\nA lot of [these books] are by multiple authors. And a lot of them don't do clinical medicine. I think really of the clinicians that I would say I have a lot of respect for, I think Bonnie Goldstein’s [book] is really the only other one [that’s similar]. \n\n### Is there anything that got left out of your cannabis guidebook that you wish you could’ve included? \n\nSince [the book] has come out, there've been a lot of changes [in the cannabis space]. I almost feel like there should be a second edition. I almost feel like it's going to need to be updated maybe in another year—now with Epidiolex, with the studies that have come out in Israel with autism, new states that are now on board with legalized cannabis, and state regulations have shifted and changed. \n\nIf anything, maybe it would've been fun to put more history. I really think the history of cannabis as a medicine is pretty fascinating. But I’m actually pretty satisfied with what got covered. \n\nIf you’re new to cannabis and want to learn more, take a look at our [Cannabis 101](https://hellomd.com/articles/cannabis-101-what-you-need-to-know-about-marijuana/) index of articles. And if you have questions about cannabis, [ask them](https://www.hellomd.com/) and our community will answer.","image":{"childImageSharp":{"fluid":{"base64":"data:image/jpeg;base64,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","aspectRatio":1.3605442176870748,"src":"/static/8b8a9a79af0254a13db11c3bb8e04e41/14b42/2e668269dc77f1e90bd1c0991dab006d.jpg","srcSet":"/static/8b8a9a79af0254a13db11c3bb8e04e41/f836f/2e668269dc77f1e90bd1c0991dab006d.jpg 200w,\n/static/8b8a9a79af0254a13db11c3bb8e04e41/2244e/2e668269dc77f1e90bd1c0991dab006d.jpg 400w,\n/static/8b8a9a79af0254a13db11c3bb8e04e41/14b42/2e668269dc77f1e90bd1c0991dab006d.jpg 800w,\n/static/8b8a9a79af0254a13db11c3bb8e04e41/47498/2e668269dc77f1e90bd1c0991dab006d.jpg 1200w,\n/static/8b8a9a79af0254a13db11c3bb8e04e41/acffd/2e668269dc77f1e90bd1c0991dab006d.jpg 1435w","srcWebp":"/static/8b8a9a79af0254a13db11c3bb8e04e41/58556/2e668269dc77f1e90bd1c0991dab006d.webp","srcSetWebp":"/static/8b8a9a79af0254a13db11c3bb8e04e41/61e93/2e668269dc77f1e90bd1c0991dab006d.webp 200w,\n/static/8b8a9a79af0254a13db11c3bb8e04e41/1f5c5/2e668269dc77f1e90bd1c0991dab006d.webp 400w,\n/static/8b8a9a79af0254a13db11c3bb8e04e41/58556/2e668269dc77f1e90bd1c0991dab006d.webp 800w,\n/static/8b8a9a79af0254a13db11c3bb8e04e41/99238/2e668269dc77f1e90bd1c0991dab006d.webp 1200w,\n/static/8b8a9a79af0254a13db11c3bb8e04e41/0a0ac/2e668269dc77f1e90bd1c0991dab006d.webp 1435w","sizes":"(max-width: 800px) 100vw, 800px"}}}}},{"node":{"id":"Article_2825-markdown","title":"NCAA Bans the Use of Seizure-Preventing CBD Oil","slug":"ncaa-bans-the-use-of-seizure-preventing-cbd-oil","content":"Imagine working your entire life towards your dream, only to have it snatched away because of an outdated policy. This is exactly what’s happening to C.J. Harris, a talented high school football player who was recruited to play college football at Auburn. \n\nHarris thought his football dreams had come true, but then he got the terrible news: He could only play football if he stopped taking his medication—the cannabidiol (CBD) oil that controls his seizures. \n\nFOLLOW US ON [FACEBOOK](https://www.facebook.com/pg/hellomdcompany/posts/) & [INSTAGRAM](https://www.instagram.com/hellomd_com/?hl=en)\n\n### C.J.’s Story of Seizures & How CBD Helps \n\nC.J. has been battling seizures since the eighth grade. By sophomore year of high school, the problem had escalated to two to three seizures per month. \n\nLooking for a workable treatment, C.J. tried out a variety of pharmaceutical options. Unfortunately, like [30–40% of those with seizures, the traditional anti-seizure medications were ineffective for him](https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Hope-Through-Research/Epilepsies-and-Seizures-Hope-Through#3109_29). That’s when doctors decided to put him on an alternative treatment that had shown promising results for others: CBD.\n\nCBD is a cannabinoid, or chemical, derived from the cannabis plant known for its ability to calm and even prevent seizures. \n\nRELATED: [EPILEPSY RELIEF POSSIBLE THROUGH MEDICAL CANNABIS](https://www.hellomd.com/health-wellness/55c28a2c65663200065c0000/epilepsy-relief-possible-through-medical-cannabis)\n\nThe results were incredible. Since starting the CBD oil in January 2017, Harris hasn’t had a single seizure. With his condition completely under control, Harris went on to lead his high school football team to the state championship game. \n\nC.J.’s performance caught the eye of recruiters from Auburn, who offered him a spot on its team; it’s one of the top college football programs in the country. \n\nIt was a dream come true for C.J., but soon he received some crushing news. The National Collegiate Athletic Association (NCAA) reviewed his medical files, and they wouldn’t let C.J. play while he had CBD in his system. As a cannabis-derived product, CBD is banned in college football with no exceptions. \n\nC.J. was left with an impossible choice: Give up his football dreams or go back to having regular seizures. Of course, stopping his medication wasn’t really option, because he had no other treatment alternatives—and having dangerous seizures wouldn’t be safe.\n\nSadly, he remains ineligible to play, despite all of his skill, talent and hard work. \n\n### C.J. Isn’t the Only One Taking CBD for Seizures \n\nAfter his story was widely reported, C.J. received a stream of supportive messages from many, including state representatives, epilepsy foundations and other athletes. They all urged the NCAA and Auburn to reconsider their decision.\n\nJerry Kill, who was Big Ten Coach of the Year while coaching the University of Minnesota football team, has battled seizures himself and harshly criticized the choice to ban C.J. \n\n\"That young man should not be punished for a disorder that is being controlled by cannabis oil,\" said Jerry. \"I encourage both parties to take a good look at what they're doing to a young man's dream. … A kid should not be punished for his seizures being brought under control. It's not fair to the kid.\"\n\nC.J. isn’t the only one taking CBD for seizures. CBD has been shown to be a safe and effective option. Studies show that [taking CBD can lead to a vast improvement in seizure disorders](https://nyulangone.org/press-releases/medical-marijuana-extract-curbs-seizure-frequency-in-early-trial-of-epilepsy-patients)—reducing the frequency of seizures or even stopping them completely. \n\nCBD is legal for medical use in many states, with hemp-derived CBD available nationwide. It’s [non-psychoactive, non-addictive and without any known negative side effects](http://www.who.int/medicines/access/controlled-substances/5.2_CBD.pdf) according to the World Health Organization.\n\nEven the pharmaceutical industry seems to be giving CBD its stamp of approval. Pharma giant GW Pharmaceuticals recently developed a CBD-based medicine for epilepsy called Epidiolex. [Epidiolex even made it through FDA approval](http://ir.gwpharm.com/news-releases/news-release-details/gw-pharmaceuticals-plc-and-its-us-subsidiary-greenwich). \n\nYet, despite these developments, CBD continues to be banned for athletes. \n\n### A Call to Ease the Ban on Cannabis for Athletes \n\nC.J.’s story has made more people think about why most sports leagues continue to ban cannabis. From managing pre-existing health conditions to treating the side effects of sports-related injuries such as concussions and chronic pain, cannabis has shown promising results. But in the U.S., almost all sports organizations ban cannabis, even isolated forms of non-psychoactive CBD. \n\nNow athletes from many different sports are [advocating for access to this life-altering—and sometimes life-saving—medicine](https://www.mensjournal.com/health-fitness/18-of-the-biggest-marijuana-advocates-in-pro-sports-w429975/). From former pro-football stars like Ricky Williams and Jake Plumber to former NBA players like Cliff Robinson to pro mixed-martial artists like Nick Diaz, many are calling for sports leagues to reconsider their cannabis bans.\n\nOf course, there are a few notable exceptions to the blanket ban on cannabis in American sports. [The NHL doesn’t mention cannabis on its list of banned substances](https://www.cashinbis.com/mlb-nba-and-nfls-policy-on-cannabis/) at all. And some former NHL players like Riley Cote have been vocal about their own cannabis use for hockey-related injuries and pain. \n\nThe World Anti-Doping Association (WADA), the organization that regulates which substances are allowed in the Olympics, recently changed its rules on CBD. While all other cannabis is still banned, [WADA made an exception for CBD—adding it to the list of acceptable treatments](https://www.usada.org/wp-content/uploads/wada-2018-prohibited-list-en.pdf).\n\nWADA usually sets the international standards for what’s allowed in sports, with many organizations taking on these standards themselves. But with the exception of a new minor league basketball organization, the North American Premier Basketball League (NAPB), few in the U.S. have followed suit.\n\nHopefully, as public support for cannabis and CBD continues to grow, we’ll start to see more changes in these policies. Our athletes go through so much physical hardship for our entertainment. The least we can do is allow those who rely on CBD, like C.J. Harris, to continue to use the medicine that keeps them healthy.\n\nPhoto credit: [Pixabay](https://www.pexels.com/@pixabay)\n\nIf you’re new to cannabis and want to learn more, take a look at our [Cannabis 101](https://www.hellomd.com/health-wellness/5b8882d88dd0720008373fcf/cannabis-101-what-you-need-to-know-to-about-marijuana) index of articles. [HelloMD](https://www.hellomd.com/) can help you get your medical marijuana recommendation; it's 100% online, private and efficient. \n","image":{"childImageSharp":{"fluid":{"base64":"data:image/jpeg;base64,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","aspectRatio":1.3793103448275863,"src":"/static/3ea9c2c3a4a8d6f7cf48357c4ce2d87d/14b42/2b6ec9699ef0149c7e0d8f4c129d573e.jpg","srcSet":"/static/3ea9c2c3a4a8d6f7cf48357c4ce2d87d/f836f/2b6ec9699ef0149c7e0d8f4c129d573e.jpg 200w,\n/static/3ea9c2c3a4a8d6f7cf48357c4ce2d87d/2244e/2b6ec9699ef0149c7e0d8f4c129d573e.jpg 400w,\n/static/3ea9c2c3a4a8d6f7cf48357c4ce2d87d/14b42/2b6ec9699ef0149c7e0d8f4c129d573e.jpg 800w,\n/static/3ea9c2c3a4a8d6f7cf48357c4ce2d87d/47498/2b6ec9699ef0149c7e0d8f4c129d573e.jpg 1200w,\n/static/3ea9c2c3a4a8d6f7cf48357c4ce2d87d/0e329/2b6ec9699ef0149c7e0d8f4c129d573e.jpg 1600w,\n/static/3ea9c2c3a4a8d6f7cf48357c4ce2d87d/d5645/2b6ec9699ef0149c7e0d8f4c129d573e.jpg 2834w","srcWebp":"/static/3ea9c2c3a4a8d6f7cf48357c4ce2d87d/58556/2b6ec9699ef0149c7e0d8f4c129d573e.webp","srcSetWebp":"/static/3ea9c2c3a4a8d6f7cf48357c4ce2d87d/61e93/2b6ec9699ef0149c7e0d8f4c129d573e.webp 200w,\n/static/3ea9c2c3a4a8d6f7cf48357c4ce2d87d/1f5c5/2b6ec9699ef0149c7e0d8f4c129d573e.webp 400w,\n/static/3ea9c2c3a4a8d6f7cf48357c4ce2d87d/58556/2b6ec9699ef0149c7e0d8f4c129d573e.webp 800w,\n/static/3ea9c2c3a4a8d6f7cf48357c4ce2d87d/99238/2b6ec9699ef0149c7e0d8f4c129d573e.webp 1200w,\n/static/3ea9c2c3a4a8d6f7cf48357c4ce2d87d/7c22d/2b6ec9699ef0149c7e0d8f4c129d573e.webp 1600w,\n/static/3ea9c2c3a4a8d6f7cf48357c4ce2d87d/baba5/2b6ec9699ef0149c7e0d8f4c129d573e.webp 2834w","sizes":"(max-width: 800px) 100vw, 800px"}}}}},{"node":{"id":"Article_2805-markdown","title":"Beyond the CB1 & CB2 Cannabis Receptors: TRPV1 & GPR55 ","slug":"beyond-the-cb1-and-cb2-cannabis-receptors-trpv1-and-gpr55","content":"If you’re familiar with cannabis science, you know about CB1 and CB2, the receptors located throughout the body that are triggered by cannabinoids like tetrahydrocannabinol (THC) and cannabidiol (CBD). It’s via these receptors that THC and CBD are able to bring about some of the therapeutic effects that cannabis is known for. \n\nWhile CB1 and CB2 get the most attention—likely because we know the most about them—there are other receptors in the body that also respond to cannabinoids, like TRPV1 and GPR55. These receptors are influenced by THC and CBD, as well as [anandamide](https://www.hellomd.com/health-wellness/5a949d06f24d1300077ccb66/eating-anandamide-the-bliss-molecule) and 2-arachidonoylglycerol (2-AG), endocannabinoids made by our bodies. \n\nWe’re beginning to gain a better understanding of TRPV1 and GPR55. Both hold much therapeutic promise, and CBD may be one of the ways to unlock this potential.\n\nFOLLOW US ON [FACEBOOK](https://www.facebook.com/pg/hellomdcompany/posts/) & [INSTAGRAM](https://www.instagram.com/hellomd_com/?hl=en)\n\n### The TRPV1 Receptor Controls Our Pain Response \n\nTRPV1, also called vanilloid receptor 1 or the capsaicin receptor, helps control our body temperature and plays a role in how we feel pain. This receptor can be activated via physical and chemical cues, including:\n\n* Temperatures above 109 degrees F\n* Capsaicin, the molecule responsible for the spicy sensation of chili peppers\n* Acidic conditions in the body\n* Anandamide\n* CBD\n\nIndeed, TRPV1 is one of the few receptors we know of that CBD directly influences; CBD doesn’t really bind to CB1 or CB2. CBD’s affinity for the TRPV1 receptor may be one of the ways it brings about therapeutic effects in the body, and some studies are beginning to shed light on this. \n\nA 2004 study on rats found that [CBD acts in a similar way to capsaicin]( https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1575333/#bib2). When we eat a chili pepper, capsaicin acts on the TRPV1 receptors in our brain cells, making us feel that burning sensation we associate with spicy foods. \n\nThese brain cells then become desensitized—they no longer signal that burning sensation to our brain when capsaicin acts on TRPV1. This is perhaps why some people have a higher tolerance for spicy foods: Their TRPV1 receptors have become desensitized. \n\nBut capsaicin does more than make our mouth burn when we eat spicy foods. It also has anti-inflammatory and anti-seizure properties. \n\nThe researchers in this study think that CBD behaves in a similar way to capsaicin—except without imparting that spicy sensation. Somehow CBD desensitizes TRPV1 receptors, thus reducing our pain response. And we already know that CBD has pain-relieving effects and can help those with epilepsy—as much anecdotal evidence suggests. \n\n### Researchers Focusing on TRPV1 in Epilepsy & Endometrial Cancer Studies\n\nIndeed, TRPV1 likely has something to do with CBD’s anti-seizure abilities. Rodents with epilepsy and some human epilepsy patients tend to have more TRPV1 receptors than their healthy counterparts. It’s possible that the body makes more of these receptors in response to the condition.\n\nKnowing this, researchers decided to test the effect of CBD on mice with and without TRPV1 receptors. They subjected the mice to electric currents high enough to produce seizures and found that [mice without the TRPV1 receptors were more susceptible to seizures](http://n.neurology.org/content/90/15_Supplement/S53.004). The results suggest that CBD was acting on TRPV1 to reduce seizures, since those without TRPV1 receptors were more likely to get them after being subjected to electrical currents.\n\nMost recently, research has suggested that substances that attach to [TRPV1 may be useful in treating endometrial cancer](https://www.ncbi.nlm.nih.gov/pubmed/29441458), though this evidence is preliminary. In a petri dish, researchers exposed susceptible cells to high levels of estrogen to make them cancerous. They then monitored what happened in the presence of THC and CBD.\n\nThe researchers found that CBD, but not THC, caused these cancerous cells to die. They believe that CBD was doing this by acting on the TRPV1 receptor. While these results are promising, much more research is needed. \n\nRELATED: [CAN CANNABIS HELP DEFEND AGAINST ENDOMETRIAL CANCER?](https://www.hellomd.com/health-wellness/5adfa21c049b4f000a64e8d5/can-cannabis-help-defend-against-endometrial-cancer)\n\n### GPR55 Plays a Role in the Development of Cancer \n\nGPR55 is what’s known as a G-protein coupled receptor—the same type of receptor as CB1 and CB2. GPR55 is a likely contributor to many of cannabis’s health benefits, though we still don’t have the whole picture. \n\nThis receptor can be activated by both anandamide and 2-AG, as well as THC. Because GPR55 seems to interact with many cannabinoids, some researchers think that it could be the much-speculated-about third cannabinoid receptor, or CB3, but this hasn’t been confirmed yet. \n\nInterestingly, CBD doesn’t activate this receptor. Rather, it prevents other substances from attaching to it. Researchers think that this special quality may be one of the reasons behind CBD’s therapeutic effects, and they think it could have applications in many conditions including cancer, gastrointestinal inflammation and certain seizures. \n\nResearch links [GPR55 activation with tumor activity]( https://www.ncbi.nlm.nih.gov/pubmed/28029647). Thus, something that prevents substances from binding to this receptor, like CBD, could have an anti-tumor effect, though the molecule’s capacity to do this hasn’t been tested yet. \n\nSo far, researchers have tested the ability of substances that block GPR55 in the following cancers: \n\n* Brain\n* Breast\n* Colorectal\n* Pancreatic \n\nThe results have been positive, though it’s important to remember that these studies were preliminary.\n\n### How GPR55 Impacts Inflammatory Bowel Disease & Dravet Syndrome \n\nWe know that CBD has anti-inflammatory properties. Yet we don’t know why it tends to provide relief for folks who suffer from inflammation of the colon and intestines, commonly known as inflammatory bowel disease. Here, GPR55 may again be part of the answer.\n\nPeople with Crohn’s disease and ulcerative colitis tend to have more GPR55 receptors in their bodies than their healthy counterparts do. And studies on mice where molecules block GPR55 lead to [a reduction in intestinal inflammation]( https://onlinelibrary.wiley.com/doi/full/10.1111/nmo.12639). We’ll have to wait and see whether or not CBD has similar effects in future studies. \n\nThough it’s likely that TRPV1 has something to do with CBD’s anti-seizure properties, GPR55 may be doing something as well. In order to better understand why patients with Dravet syndrome, a severe form of epilepsy, tend to respond favorably to CBD, researchers tested the effect of CBD in a mouse model of this condition.\n\nThey found that [CBD reduced seizure activity by binding to GPR55 receptors]( http://www.pnas.org/content/114/42/11229) in the hippocampus, a part of the brain that seems to play an important role in seizure activity. \n\nThe anti-seizure activities that can be credited to both GPR55 and TRPV1 highlight how many different factors must come together to produce cannabis’s therapeutic effects. CB1, CB2, TRPV1 and GPR55 are just some of the receptors in the body that THC and CBD interact with—there are many more that researchers are just beginning to understand. \n\nCannabinoid science is a field of study that’s still in its infancy. As research progresses, it’ll paint a clearer picture of the endocannabinoid system and how cannabis can be used to its full medical potential. \n\nIf you’re new to cannabis and want to learn more, take a look at our [Cannabis 101]( https://www.hellomd.com/health-wellness/56201c206430320006bb0000/cannabis-101-your-quick-guide-to-medical-marijuana) post. [HelloMD](https://www.hellomd.com/) can help you get your medical marijuana recommendation; it's easy, private and 100% online.  \n","image":{"childImageSharp":{"fluid":{"base64":"data:image/jpeg;base64,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","aspectRatio":1.3888888888888888,"src":"/static/8fb12afbb21296eeb48bdf453942b83a/14b42/f9596d6d523e2f3497565079ae40bc21.jpg","srcSet":"/static/8fb12afbb21296eeb48bdf453942b83a/f836f/f9596d6d523e2f3497565079ae40bc21.jpg 200w,\n/static/8fb12afbb21296eeb48bdf453942b83a/2244e/f9596d6d523e2f3497565079ae40bc21.jpg 400w,\n/static/8fb12afbb21296eeb48bdf453942b83a/14b42/f9596d6d523e2f3497565079ae40bc21.jpg 800w,\n/static/8fb12afbb21296eeb48bdf453942b83a/47498/f9596d6d523e2f3497565079ae40bc21.jpg 1200w,\n/static/8fb12afbb21296eeb48bdf453942b83a/19e6b/f9596d6d523e2f3497565079ae40bc21.jpg 1469w","srcWebp":"/static/8fb12afbb21296eeb48bdf453942b83a/58556/f9596d6d523e2f3497565079ae40bc21.webp","srcSetWebp":"/static/8fb12afbb21296eeb48bdf453942b83a/61e93/f9596d6d523e2f3497565079ae40bc21.webp 200w,\n/static/8fb12afbb21296eeb48bdf453942b83a/1f5c5/f9596d6d523e2f3497565079ae40bc21.webp 400w,\n/static/8fb12afbb21296eeb48bdf453942b83a/58556/f9596d6d523e2f3497565079ae40bc21.webp 800w,\n/static/8fb12afbb21296eeb48bdf453942b83a/99238/f9596d6d523e2f3497565079ae40bc21.webp 1200w,\n/static/8fb12afbb21296eeb48bdf453942b83a/a7d4f/f9596d6d523e2f3497565079ae40bc21.webp 1469w","sizes":"(max-width: 800px) 100vw, 800px"}}}}},{"node":{"id":"Article_2779-markdown","title":"How Hemp CBD Oil Can Help Kids With Seizures","slug":"how-hemp-cbd-oil-can-help-kids-with-seizures","content":"Stories of treating epileptic children with cannabidiol (CBD) oil have been prolific in the media in the last few years. Arguably, these stories ignited and sustained the rapidly changing opinion Americans have towards medical marijuana—29 states plus Washington D.C. have legalized some form of medicinal cannabis. It seems that stories of miraculous medical recoveries have resonated enough with voters to create real cannabis policy change. \n\nFOLLOW US ON [FACEBOOK](https://www.facebook.com/pg/hellomdcompany/posts/) & [INSTAGRAM](https://www.instagram.com/hellomd_com/?hl=en)\n\n### Charlotte’s Story Showcases the Power of CBD for Seizures \n\nMany of these stories involve kids younger than 10 years of age who are severely debilitated from near-constant seizures. These children are out of options due to ineffective pharmaceutical treatments.\n\nOne such child was Charlotte Figi. Charlotte was just five years old when her doctors informed her parents there was nothing else they could do to treat her [Dravet syndrome](https://www.dravetfoundation.org/what-is-dravet-syndrome/). When her parents turned to CBD as a last hope, Charlotte was suffering from 300 grand mal seizures per week. The seizures were so constant that she lost the ability to walk.\n\nAfter winning the right to register Charlotte as the youngest medical marijuana patient in the state of Colorado, her parents began working with cannabis growers who were cultivating high-CBD, low-tetrahydrocannabinol (THC) cannabis strains. These growers bred a special strain with these characteristics just for her and named it Charlotte’s Web. \n\nWithin one year of taking the CBD oil, Charlotte was a thriving six year old experiencing just two to three seizures per month.\n\nAll across America, parents are finding life-saving medicine for their children in some form of the cannabis sativa plant. In states with no medicinal cannabis laws, the only form of CBD that’s legal comes from hemp. If you’re a parent looking into hemp CBD for your child, here are some answers to the most pressing questions you may have about CBD treatments for kids.  \n\n### Why Consider Hemp CBD Oil?\n\nCBD, unlike THC, doesn’t make you feel high. For many parents, a natural plant extract that comes with powerful medicinal benefits, but won’t get their kid stoned is a dream come true. And for hemp-derived CBD oil to be legal, it has to test at less than 0.3% THC. Hemp CBD’s non-psychoactivity helps parents feel more open to giving it to their suffering child. \n\nHemp CBD oil is also very accessible. CBD that you’d find in a cannabis dispensary comes from a different variety of _Cannabis sativa_ plant. This different variety has much higher levels of cannabinoids and terpenes, and is only legal for adult use or medical marijuana patients with very specific ailments, depending on the state. But hemp-based CBD is regulated by different rules. \n\nRELATED: [CBD OIL VS. HEMP OIL](https://www.hellomd.com/health-wellness/5b16ba68bf4c4d000a0e742d/cbd-oil-vs-hemp-oil-whats-the-difference)\n\nHemp CBD isn’t made from cannabis flower, like controlled CBD products are, but rather, is made from the stalk and seeds. This means hemp CBD has a much lower level of all cannabinoids, including THC and CBD.\n\nBecause hemp CBD is made from the stalks and seeds, it can get around the Controlled Substances Act and the Food and Drug Administration (FDA) doesn’t regulate it like it does whole-plant cannabis CBD. This means for the most part it’s regulated similarly to diet supplements and vitamins and can be sold all throughout the country. \n\n### How Does Hemp CBD Oil Treat Medical Conditions in Children?\n\nWhen it comes to treating children with CBD, epilepsy and seizures in general have been the most notable health conditions the oil seems to help with. There’ve been many clinical trials and lab research to indicate CBD is an effective treatment for seizures. \n\nSeizures are caused when brain cells misfire, which cause the body to convulse and can lead to loss of consciousness, injury and brain damage. So why is CBD so effective in treating seizure conditions? \n\nSome researchers believe that CBD interacts with:\n\n* endocannabinoid receptors \n* calcium and sodium ion channels \n* glutamate receptor antagonists\n\nIn this theory, the anticonvulsive properties of CBD attach to neurons in the brain and inhibit how the ions flow between neurotransmitters. Unfortunately, this is only a theory, and much more research must be conducted to fully understand the science behind the anticonvulsive properties of CBD. \n\n### Does Hemp CBD Work Better Than Traditional Treatments Do?\n\nEvidence from lab research, clinical trials and anecdotal stories have all shown positive signs that cannabis can help with epilepsy. Especially in extreme cases in which doctors, equipped with only pharmaceutical treatment options, have essentially conceded the battle. \n\nAnd even if anticonvulsive pharmaceutical drugs like valproic acid, primidone, clonazepam and phenobarbital are effective against seizures, they come with some pretty serious side effects that can do real damage to young, developing children. These drugs are known to result in: \n\n* Nausea \n* Hair loss \n* Liver failure \n* Depression \n* Weight gain \n* Irritability\n* Sedation\n* Mood disorders\n* Impotence\n\nLuckily, right now there’s more scientific attention on CBD as a natural treatment for epilepsy than there has ever been. And in a monumental move, the FDA just approved Epidiolex, a CBD-based syrup to treat seizures associated with Lennox-Gastaut syndrome and Dravet syndrome. \n\nAmong the rigorous testing to receive FDA approval was [a double-blind, placebo-controlled study that was published in _The New England Journal of Medicine_](https://www.nejm.org/doi/full/10.1056/NEJMoa1611618) and funded by GW Pharmaceuticals, the maker of Epidiolex. In this study, 120 children and teenagers with Dravet syndrome were divided into two groups: one treated with the CBD oral solution and the other treated with a placebo. The groups were treated for 14 weeks with either 20 mg of CBD per kilogram of body weight per day or the placebo. \n\nAfter 14 weeks, the group taking CBD saw a reduction in seizures per month from 12.4 to 5.9 (median). This is compared to a decrease from 14.9 to 14.1 (median) when treated with the placebo. Sixty-two percent of caregivers in the CBD group reported that the child’s overall condition improved, compared to just 34% in the placebo group.\n\nThe results of this study led the lead researcher Orrin Devinsky, to conclude, “This study clearly establishes cannabidiol as an effective anti-seizure drug for this disorder and this age group.” \n\nThese subjects had very difficult cases, in which their seizures were extremely drug-resistant, rendering traditional treatments pretty much ineffective. And compared to the side effects of traditional drugs, in this study the most reported side effect was sleepiness. For this group of patients to see success using a natural extract is revolutionary. For them, CBD was certainly more effective than traditional treatments were. \n\n### Can I Legally Give Hemp CBD to My Kid?\n\nHemp CBD oil is legally much more accessible than CBD oil is. The difference between hemp-derived CBD and cannabis-derived CBD can be confusing, but according to a Drug and Enforcement Agency (DEA) spokesperson, “If the products are derived from the non-psychoactive part of the marijuana plant, then you’re talking a non-controlled substance.”  If these requirements are met, then hemp CBD oil can be legally sold all throughout the United States. \n\n### How Does a Parent Get Hemp CBD Oil for Their Kid?\n\nFinding hemp CBD oil is relatively simple. You can find it in most cities and towns across America, often at organic food stores and holistic shops or through a state program. Hemp CBD oil can also be legally shipped anywhere in the U.S.\n\nBut parents should do research on a specific brand before buying, especially since these oils have relatively lax regulations on their ingredients and production methods. You always want to make sure there aren’t any harmful additives or questionable production methods employed when processing the hemp oil.\n\nThe real struggle for many parents occurs after purchasing the CBD. How do you use it? How much is enough? How much is too much? First of all, discuss hemp CBD oil with your child’s doctor before you do anything. They may have suggestions for dose and treatment or hopefully some kind of general guidance to give to you.\n\nUnfortunately, not many doctors are fully versed in the latest science and research on CBD. In these cases, many parents may be left trying to make sense of the research, dosing and treatment plans on their own.\n\nWith this in mind, parents and caregivers can join networks so that they don’t have to go on this journey alone. [Realm of Caring](https://www.theroc.us/), started by the Stanley Brothers who cultivated Charlotte’s Web, exists as a resource for those treating illness with CBD. Parents can find dosage calculators, treatment plan suggestions and a community of other parents on the same journey. \n\nHelloMD also offers a wonderful community of nurses and doctors who are well versed in cannabinoids and medical conditions, medicinal marijuana patients and their caregivers, plus cannabis industry experts who can all share their knowledge and lend support. \n\nPhoto credit: [MI PHAM](https://unsplash.com/@phammi)\n","image":{"childImageSharp":{"fluid":{"base64":"data:image/jpeg;base64,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","aspectRatio":1.3793103448275863,"src":"/static/3b1f851ce51e1cb7c2b19ac0e4b4d0e4/14b42/bdb0330768895be26b074df025a0e912.jpg","srcSet":"/static/3b1f851ce51e1cb7c2b19ac0e4b4d0e4/f836f/bdb0330768895be26b074df025a0e912.jpg 200w,\n/static/3b1f851ce51e1cb7c2b19ac0e4b4d0e4/2244e/bdb0330768895be26b074df025a0e912.jpg 400w,\n/static/3b1f851ce51e1cb7c2b19ac0e4b4d0e4/14b42/bdb0330768895be26b074df025a0e912.jpg 800w,\n/static/3b1f851ce51e1cb7c2b19ac0e4b4d0e4/47498/bdb0330768895be26b074df025a0e912.jpg 1200w,\n/static/3b1f851ce51e1cb7c2b19ac0e4b4d0e4/0e329/bdb0330768895be26b074df025a0e912.jpg 1600w,\n/static/3b1f851ce51e1cb7c2b19ac0e4b4d0e4/db203/bdb0330768895be26b074df025a0e912.jpg 3642w","srcWebp":"/static/3b1f851ce51e1cb7c2b19ac0e4b4d0e4/58556/bdb0330768895be26b074df025a0e912.webp","srcSetWebp":"/static/3b1f851ce51e1cb7c2b19ac0e4b4d0e4/61e93/bdb0330768895be26b074df025a0e912.webp 200w,\n/static/3b1f851ce51e1cb7c2b19ac0e4b4d0e4/1f5c5/bdb0330768895be26b074df025a0e912.webp 400w,\n/static/3b1f851ce51e1cb7c2b19ac0e4b4d0e4/58556/bdb0330768895be26b074df025a0e912.webp 800w,\n/static/3b1f851ce51e1cb7c2b19ac0e4b4d0e4/99238/bdb0330768895be26b074df025a0e912.webp 1200w,\n/static/3b1f851ce51e1cb7c2b19ac0e4b4d0e4/7c22d/bdb0330768895be26b074df025a0e912.webp 1600w,\n/static/3b1f851ce51e1cb7c2b19ac0e4b4d0e4/62b7a/bdb0330768895be26b074df025a0e912.webp 3642w","sizes":"(max-width: 800px) 100vw, 800px"}}}}},{"node":{"id":"Article_2729-markdown","title":"Controlling Epilepsy With Cannabis & the Keto Diet","slug":"controlling-epilepsy-with-cannabis-and-the-keto-diet","content":"In early 2018, Illinois sixth-grader Ashley Surin won a major legal victory: [the right to have access to medical marijuana at school](http://www.chicagotribune.com/suburbs/ct-met-suburban-student-medical-marijuana-hearing-20180112-story.html). The middle schooler had been suffering daily seizures since undergoing treatment for leukemia. And standard antiseizure medications hadn’t worked well for her. \n\nBut Ashley’s parents say that since starting a regimen of cannabis drops combined with the ultra-restrictive ketogenic diet, her seizures have dwindled to about one a month. Research reveals that for people like Ashley, marijuana and the keto diet may be better at controlling severe seizures than mainstream pharmaceuticals are. \n\nFOLLOW US ON [FACEBOOK](https://www.facebook.com/pg/hellomdcompany/posts/) & [INSTAGRAM](https://www.instagram.com/hellomd_com/?hl=en)\n\n### What Causes Seizures?\n\nSeizures can have a variety of causes, and people of any age can experience just one or many seizures. Common conditions that can contribute to seizures include: \n\n* Abnormal levels of sodium (salt) or glucose (sugar) in the blood\n* Congenital brain defects that predispose a person to lifelong seizures\n* Head injuries\n* High fevers\n* Stroke\n* Very high blood pressure\n* Toxin accumulation in the bloodstream\n* Withdrawal from alcohol or drug use—including some prescription drugs\n\nEpilepsy is the term used for a variety of disorders that are characterized by recurring seizures. Epileptic seizures can range from very minor episodes that cause symptoms like sudden blinking, all the way to the very debilitating grand mal seizures that have a severe impact on all aspects of a person’s life.\n\nIn all of these cases, [seizures have a common cause: abnormal electrical signaling in the brain](https://medlineplus.gov/ency/article/003200.htm), particularly the hippocampus. A number of medications have been developed to control seizures and stop the disruption of electrical impulses within the brain. But these medications can have serious side effects, and in some cases, they simply don’t work. \n\nRELATED: [EPILEPSY RELIEF POSSIBLE THROUGH MEDICAL CANNABIS](https://www.hellomd.com/health-wellness/55c28a2c65663200065c0000/epilepsy-relief-possible-through-medical-cannabis)\n\n### The Ketogenic Diet Protects the Brain\n\nIn the early 1930s, doctors noted that fasting—extended periods without food— could reduce seizure activity. Until the widespread development of today’s antiseizure medications, diet was widely used to treat epilepsy.\n\nNow, research supports these early protocols. There’s evidence that the ketogenic diet—a highly restrictive diet that gets most of its calories from fat—[can reduce the incidence of seizures in children by at least half](https://www.epilepsy.com/learn/treating-seizures-and-epilepsy/dietary-therapies/ketogenic-diet). The keto diet also has benefits for adults with epilepsy.\n\n[The keto diet gets its name from the result it produces](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898565/). Normally, the body gets most of its energy from protein and carbohydrates. The body needs some fats, but the typical “healthy” diet usually restricts them, especially the saturated fats that come from animal products.\n\nBut the ketogenic diet turns these recommendations upside down. For those following the diet, 90% of their calories come from saturated and other kinds of “unhealthy” fats. Carbohydrates are virtually nonexistent on the keto diet.\n\nWhen the body burns fat for energy, it produces molecules called ketone bodies. It’s these bodies that hold the key to the antiseizure properties of the ketogenic diet. Research on the antiseizure effects of ketones suggests that [ketone bodies can increase the number of mitochondria in the brain’s hippocampus](https://www.sciencedaily.com/releases/2005/11/051114220938.htm). Mitochondria are responsible for energy production on a cellular level. And increasing energy output in the hippocampus appears to help stabilize neurons and strengthen neural pathways. In this way, the brain can better withstand episodes of abnormal electrical activity that are associated with seizures.\n\n### Cannabis Supports the Brain’s Own Seizure Control\n\nThe cannabis compound responsible for supporting seizure control in the brain appears to be cannabidiol (CBD). Some studies indicate that the psychoactive compound tetrahydrocannabinol (THC) can actually stimulate seizure activity, especially in people who already have a seizure disorder. But CBD has a long list of properties that support cellular and neural health throughout the body. \n\nResearch has revealed that CBD:\n\n* Can be a powerful neuroprotectant that can help preserve brain cells even in cases of head trauma and stroke\n* [Supports endogenous, or natural, brain chemicals that inhibit seizure activity](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767492/)\n* Increases the production of gamma-aminobutyric acid, or GABA, a powerful inhibitory neurotransmitter that suppresses seizure activity \n* [Supports the production of adenosine](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577085/), a natural anticonvulsant brain chemical that’s activated by the abnormal electrical activity that marks a seizure\n\nThis research hasn’t been lost on the Federal Drug Administration (FDA), which has cautiously granted approval to a distillate of pure CBD oil called Epidiolex. This is meant as a last resort when all other treatments fail. \n\nLooking at all of this data, it’s no wonder that epilepsy patients turn to both cannabis and the keto diet to help treat their seizures. With the keto diet, the ketones produced kick-start a process that raises energy in the hippocampus, stabilizing the brain and neural pathways. Meanwhile, cannabis supports other chemicals that inhibit seizures and supports good cell health.\n\nFor epilepsy patients who consume cannabis and a keto diet, it means they’re taking a two-pronged treatment approach: altering body chemistry to protect the brain and supporting the brain’s own defenses against seizures. \n\n### Standard Epilepsy Medications Can Reduce Seizures\n\nThat said, standard medical treatments for epilepsy such as [antiseizure drugs also appear to work well](https://www.epilepsysociety.org.uk/how-anti-epileptic-drugs-work#.WyVvHhJKi_U). These medications usually:\n\n* Target the various pathways that regulate energy\n* Affect transmission between neurons\n* Boost the activity of natural anticonvulsants like GABA\n\nSimilar to cannabis and the ketogenic diet, these drugs affect the same mechanisms that trigger—or inhibit—seizures. But these medications can have severe side effects, and for many epilepsy patients, they aren’t effective. For these individuals and others like Ashley, nonpharmaceutical alternatives like cannabis and the ketogenic diet offer a different route to the same result: fewer seizures and better health.\n\nPhoto credit: [Markus Spiske](https://unsplash.com/@markusspiske)\n\nIf you’re new to cannabis and want to learn more, take a look at our [Cannabis 101](https://www.hellomd.com/health-wellness/56201c206430320006bb0000/cannabis-101-your-quick-guide-to-medical-marijuana) post. [HelloMD](https://www.hellomd.com/) can help you get your medical marijuana recommendation; it's easy, private and 100% online.  \n","image":{"childImageSharp":{"fluid":{"base64":"data:image/jpeg;base64,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","aspectRatio":1.3793103448275863,"src":"/static/89bf8ecb95a86cda3fee22d727203ffe/14b42/2abd77b26a0c768f9252709eb9c67b18.jpg","srcSet":"/static/89bf8ecb95a86cda3fee22d727203ffe/f836f/2abd77b26a0c768f9252709eb9c67b18.jpg 200w,\n/static/89bf8ecb95a86cda3fee22d727203ffe/2244e/2abd77b26a0c768f9252709eb9c67b18.jpg 400w,\n/static/89bf8ecb95a86cda3fee22d727203ffe/14b42/2abd77b26a0c768f9252709eb9c67b18.jpg 800w,\n/static/89bf8ecb95a86cda3fee22d727203ffe/47498/2abd77b26a0c768f9252709eb9c67b18.jpg 1200w,\n/static/89bf8ecb95a86cda3fee22d727203ffe/0e329/2abd77b26a0c768f9252709eb9c67b18.jpg 1600w,\n/static/89bf8ecb95a86cda3fee22d727203ffe/43576/2abd77b26a0c768f9252709eb9c67b18.jpg 3653w","srcWebp":"/static/89bf8ecb95a86cda3fee22d727203ffe/58556/2abd77b26a0c768f9252709eb9c67b18.webp","srcSetWebp":"/static/89bf8ecb95a86cda3fee22d727203ffe/61e93/2abd77b26a0c768f9252709eb9c67b18.webp 200w,\n/static/89bf8ecb95a86cda3fee22d727203ffe/1f5c5/2abd77b26a0c768f9252709eb9c67b18.webp 400w,\n/static/89bf8ecb95a86cda3fee22d727203ffe/58556/2abd77b26a0c768f9252709eb9c67b18.webp 800w,\n/static/89bf8ecb95a86cda3fee22d727203ffe/99238/2abd77b26a0c768f9252709eb9c67b18.webp 1200w,\n/static/89bf8ecb95a86cda3fee22d727203ffe/7c22d/2abd77b26a0c768f9252709eb9c67b18.webp 1600w,\n/static/89bf8ecb95a86cda3fee22d727203ffe/35449/2abd77b26a0c768f9252709eb9c67b18.webp 3653w","sizes":"(max-width: 800px) 100vw, 800px"}}}}},{"node":{"id":"Article_2309-markdown","title":"Can Cannabis Cause or Prevent Seizures?","slug":"can-cannabis-cause-or-prevent-seizures","content":"Recent studies published within six months of each other make two diametrically opposed claims: One points to cannabis as the likely cause of seizures while the other states that cannabis may prevent them. But the connection between marijuana and seizures is a complex one. And while these studies are grabbing headlines for their contradictory statements, it’s important to remember that they arise from highly limited studies that don’t involve the kinds of “natural” cannabis products typically used for medicinal purposes.\n\nFOLLOW US ON [FACEBOOK](https://www.facebook.com/pg/hellomdcompany/posts/) & [INSTAGRAM](https://www.instagram.com/hellomd_com/?hl=en)\n\n### Marijuana & Seizures: A Complicated Relationship\n\nThe question of whether—and how—cannabis can affect seizure activity in the brain has been raised numerous times. Anecdotal evidence from a number of medical cannabis consumers says that it can in both ways. \n\nPeople with seizure disorders, and parents of children who have them, claim that cannabis, particularly cannabidiol (CBD), reduces the frequency and severity of seizures. Now, a study carried out in the spring of 2017 by researchers at the New York University Langone Medical Center appears to [confirm CBD’s beneficial effects](https://www.scientificamerican.com/article/marijuana-treatment-reduces-severe-epileptic-seizures/), to an extent.\n\nOn the other hand, some people say that their seizures resulted from smoking or eating cannabis, and some mainstream medical publications list seizures as a risk of cannabis use. In September 2017, another study conducted at Japan’s University of Tsukuba appeared to confirm that as well, with research that showed high doses of [tetrahydrocannabinol (THC) and “spice,” a synthetic form of marijuana, could actually trigger seizures](https://www.medicalnewstoday.com/articles/319528.php). \n\nWho’s right? The answer is skewed by the limitations of these studies, both of which are based on artificial conditions and highly specific forms of cannabis that most medical consumers don’t typically encounter.  \n\n### CBD Oil May Help Treatment-Resistant Seizures\n\nThe New York University study, and a few other studies, were prompted by comments from parents of children with severe forms of epilepsy such as Dravet Syndrome, which causes almost constant seizure activity and is often resistant to standard medications. These parents said that [cannabis was able to reduce a child’s seizure activity](https://www.epilepsy.com/learn/treating-seizures-and-epilepsy/other-treatment-approaches/medical-marijuana-and-epilepsy) when no other medications could.  \n\nRELATED: [NEW STUDY PROVES EFFICACY OF CBD FOR CHILDREN’S EPILEPSY](https://www.hellomd.com/health-wellness/594a9ddf3a69ee00319c5136/new-study-proves-efficacy-of-cbd-for-childrens-epilepsy)\n\nTo test these claims, researchers compared an FDA-approved cannabis-based medication called Epidiolex—a 99% pure CBD oil concentrate—to both a placebo and a standard epilepsy medication called Onfi. Compared to the placebo, 54% of patients taking Epidiolex had fewer seizures—and in 2%, seizures stopped altogether. Compared to Onfi though, the study found minimal differences in effectiveness. Based on these results, epilepsy specialists have cautiously allowed that Epidiolex could be used for “compassionate care” when other medications fail to work.\n\nBut that study looked only at a single, FDA-approved medication based on CBD—and the study was funded by its manufacturer, GW Pharmaceuticals. Still, this study does suggest that CBD plays a role in suppressing seizures and adds more evidence to the growing list of health benefits provided by this non-psychoactive cannabis compound. \n\n### Could THC & “Spice” Trigger Seizures?\n\nIn stark contrast, researchers in the Tsukuba study claim that cannabis can cause seizures—but only certain strains, in high doses and in mice. The study worked only with very high concentrations of natural THC, the psychoactive ingredient responsible for marijuana’s “high,” and found that in these controlled circumstances THC could in fact trigger seizures. \n\nThe same study examined the [seizure-causing effects of one form of synthetic marijuana, known as “spice”](https://www.livescience.com/57747-synthetic-marijuana-risks.html). Spice was developed in the early 2000s as a way to get the marijuana high without the traces of THC that could show on a drug test. Since then, more than 150 different variants of spice have been lab-created, all of them far more potent than natural cannabis. \n\nLike the natural cannabis compounds CBD and THC, spice in all its forms binds to the body’s natural endocannabinoid receptors. But although spice stimulates those receptors in ways similar to THC, it doesn’t behave in the body the same way that natural cannabis does, and that can cause very different effects.   \n\nWhat’s more, spice usually contains other substances that also break down and create byproducts that most likely cause actions of their own on the endocannabinoid receptors. The Japanese study focused on just one variant of spice, called JWH-018, administering it in very high doses, and found that this drug can also trigger seizures.\n\nSpice can’t replicate the health benefits of natural cannabis and is sought after mostly by recreational users for its potency and ability to cheat a drug test. And although they sound a warning about the danger of seizures caused by cannabis, the Tsukuba research team acknowledge that those results come from administering concentrated forms of THC and JWH-018 at doses far higher than the typical consumer of recreational or medicinal cannabis would ever seek out. CBD was not included in this study at all.\n\n### The Cannabis-Seizure Connection Needs More Study\n\nIt’s clear there’s a connection between cannabis and seizures, but it isn’t entirely clear what that connection is. \n\nFor now, though, research indicates—and personal experiences validate—that CBD can calm seizure activity. And mainstream healthcare professionals point out that the [risk of having a seizure from using cannabis](http://www.mayoclinic.org/drugs-supplements/marijuana/safety/hrb-20059701) is largely confined to a few specific groups: people who already have a seizure disorder, or who take anti-seizure medications or antipsychotic drugs that have their own risk of causing seizures. \n\nMore comprehensive research could unravel the complicated relationship between cannabis and seizures, but federal regulations on marijuana keep it on the DEA’s Schedule 1 of highly addictive and dangerous drugs. That makes it difficult to conduct the rigorous research that clears the air and helps cannabis consumers find the answers they’re looking for.\n\nPhoto credit: [Brian Shamblen](https://www.flickr.com/photos/23972840@N04/)\n\nIf you’re new to cannabis and want to learn more, take a look at our [Cannabis 101](https://www.hellomd.com/health-wellness/cannabis-101-your-quick-guide-to-medical-marijuana) post. [HelloMD](https://www.hellomd.com/) can help you get your medical marijuana recommendation; it's easy, private and 100% online.  \n","image":{"childImageSharp":{"fluid":{"base64":"data:image/jpeg;base64,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","aspectRatio":1.5037593984962405,"src":"/static/8a1458b1d19d701b7ef2c46df25b6626/14b42/d615f5a3a08b5c65d071caa359296ec0.jpg","srcSet":"/static/8a1458b1d19d701b7ef2c46df25b6626/f836f/d615f5a3a08b5c65d071caa359296ec0.jpg 200w,\n/static/8a1458b1d19d701b7ef2c46df25b6626/2244e/d615f5a3a08b5c65d071caa359296ec0.jpg 400w,\n/static/8a1458b1d19d701b7ef2c46df25b6626/14b42/d615f5a3a08b5c65d071caa359296ec0.jpg 800w,\n/static/8a1458b1d19d701b7ef2c46df25b6626/47498/d615f5a3a08b5c65d071caa359296ec0.jpg 1200w,\n/static/8a1458b1d19d701b7ef2c46df25b6626/a6974/d615f5a3a08b5c65d071caa359296ec0.jpg 1536w","srcWebp":"/static/8a1458b1d19d701b7ef2c46df25b6626/58556/d615f5a3a08b5c65d071caa359296ec0.webp","srcSetWebp":"/static/8a1458b1d19d701b7ef2c46df25b6626/61e93/d615f5a3a08b5c65d071caa359296ec0.webp 200w,\n/static/8a1458b1d19d701b7ef2c46df25b6626/1f5c5/d615f5a3a08b5c65d071caa359296ec0.webp 400w,\n/static/8a1458b1d19d701b7ef2c46df25b6626/58556/d615f5a3a08b5c65d071caa359296ec0.webp 800w,\n/static/8a1458b1d19d701b7ef2c46df25b6626/99238/d615f5a3a08b5c65d071caa359296ec0.webp 1200w,\n/static/8a1458b1d19d701b7ef2c46df25b6626/d5052/d615f5a3a08b5c65d071caa359296ec0.webp 1536w","sizes":"(max-width: 800px) 100vw, 800px"}}}}},{"node":{"id":"Article_2315-markdown","title":"Top 11 Health Benefits of Marijuana","slug":"top-11-health-benefits-of-marijuana","content":"Cannabis has moved out of the grey area and into its rightful position as a part of a healthy approach to overall wellness. In fact, a recent study released from Duke University and the University of Arizona found that [long-term marijuana use didn’t lead to a decline in health](http://jamanetwork.com/journals/jamapsychiatry/article-abstract/2526003). In this study, 1,000 participants from New Zealand were tracked over a 40-year period, each with a minimum of 20 years of consistent cannabis consumption—smoking, specifically. \n\nThe study found no decline in lung function as well as no increase in high blood pressure or diabetes. Nor did it detect any other deterioration in physical health. The one caveat to the study was that the researchers found high levels of gum disease among the study participants. That said, this is a factor that could very well decrease as people move away from smoking marijuana towards vaporizing cannabis as well as consuming edibles or using cannabis-infused topical products. \n\nIn addition, no similarities were found between those who engaged in long-term tobacco smoking versus long-term marijuana smoking. Avshalom Capsi, a professor of psychology and neuroscience at Duke University and the co-author of the study, said that “overall damage to physical health is not apparent in this study.” \n\nFOLLOW US ON [FACEBOOK](https://www.facebook.com/pg/hellomdcompany/posts/) & [INSTAGRAM](https://www.instagram.com/hellomd_com/?hl=en)\n\n### Top 11 Reasons Why Marijuana Is Good for You\n\nThis study adds new scientific evidence to the thousands of years of anecdotal evidence, which show that cannabis isn’t bad for your health, nor can it kill you. Meanwhile, 595,690 deaths a year in the U.S. alone are attributed to tobacco. What we’re now finding is that cannabis provides a variety of health benefits for both healthy individuals and those struggling with various illnesses. \n\nHere are 11 key—and sometimes surprising—benefits of cannabis.\n\n### Benefit #1: Cannabis Regulates Metabolism & Weight Loss\n\nA survey conducted at Nunavik Inuit Health in 2004 found that the 57.4% of people in the survey, who said they used cannabis, had a lower average percentage of fat mass, body mass index and fasting insulin levels. There were statistically significant differences between the groups of people who self-reported as smoking cannabis compared to those who didn’t. \n\nSmoking cannabis in the last year was associated with a 56% lower likelihood of obesity. This is just one of the many studies that ties lower rates of obesity to cannabis consumers. Researchers found that cannabis consumers’ waists are 1.5 inches smaller on average than that of non-cannabis users. Cannabis is believed to help regulate your metabolism, also making it a factor in lowering the risk of diabetes. \n\nIn addition, for a number of folks, cannabis can get people off the couch and moving—whether it’s on the road or in the gym. In fact, some claim that marijuana increases athletic performance, for long-distance runners and swimmers in particular. Some athletes claim that it improves focus and the ability to push past previous limitations.\n\n![One benefit of marijuana: regulating metabolism & improving sports performance](https://hellomd-production.s3.amazonaws.com/articles/588fcc137bf61c000cbbd136/embedded_images/588fcc167bf61c000cbbd138/Screen_Shot_2017-01-30_at_3.20.53_PM.png)\n_One of the many benefits of marijuana is improved sports performance, especially in long-distance running._\n \n### Benefit #2: Marijuana Helps Alleviate Depression\n\nDepression is one of the most common medical conditions in the world. In a 2015 study from the University of Buffalo, RIA senior research scientist Samir Haj-Dahmane, Ph.D., said, “In the animal models we studied, we saw that chronic stress reduced the production of endocannabinoids, leading to depression-like behavior.”\n\nThis means that cannabis can be used to supplement endocannabinoids lacking within our system, helping the body return to homeostasis and in turn reducing levels of depression. Cannabis also aids in relieving stress, which is one of the biggest risk factors for depression. \n\n### Benefit #3: Cannabis Slows the Development of Alzheimer’s Disease\n\nAlzheimer’s disease is currently the sixth-leading cause of death in the United States. It also causes mental disability for those afflicted many years prior to death. A study published in the _Journal of Alzheimer’s Disease_ in September 2014 found that, “THC (tetrahydrocannabinol) could be a potential therapeutic treatment option for Alzheimer’s disease through multiple functions and pathways.” This is believed to be due to the neuroprotective and antioxidant qualities of cannabis. \n\n### Benefit #4: Cannabis Relieves Arthritis\n\nArthritis is one of the leading causes of physical disability in the world. And it’s one of the most common kinds of chronic pain that people experience. The first recorded use of cannabis to help heal arthritis was in China nearly 4,000 years ago.\n\nTetrahydrocannabinol (THC), the main active compound in most strains of marijuana, has pain-relieving and anti-inflammatory properties. In addition, cannabidiol (CBD), which is a non-psychoactive cannabinoid, helps regulate autoimmune conditions like arthritis.\n\n### Benefit #5: Marijuana Eases Chronic Pain\n\nOne of the most common reasons people miss work and have a decreased quality of life is due to various types of chronic pain. From PMS cramps to headaches to back pain, many people are debilitated by daily, overwhelming pain. Due to its anti-inflammatory and pain-relieving properties, cannabis can help reduce pain whether it’s applied in the form of a topical or consumed orally. Cannabis consumption can also help greatly decrease the need for harsh, addictive opioids. \n\n![Marijuana eases chronic pain](https://hellomd-production.s3.amazonaws.com/articles/588fcc137bf61c000cbbd136/embedded_images/588fccc42cf8a800084e13fc/Screen_Shot_2017-01-30_at_3.30.09_PM.png)\n_One of the benefits of cannabis is that it can relieve pain. Learn what the top strains for chronic pain are._\n \n### Benefit #6: Marijuana Lowers Blood Pressure\n\nOne-third of adults in the United States have high blood pressure or hypertension. This can lead to cardiovascular disease as well as strokes or heart attacks. Tobacco is one of the most common causes for high blood pressure, along with poor diet and lack of exercise.\n\nThere are a wide range of scientific and anecdotal studies to support how cannabis decreases blood pressure. Some researchers also believe that cannabinoids may have a protective role within the body, also leading to a decrease in blood pressure. \n\n### Benefit #7:  Marijuana Supports Recovery From Eating Disorders\n\nEating disorders are becoming an increasingly large problem across the world as many young people are exposed to constant media and peer pressure to be unattainably beautiful and thin. Cannabis can help regulate eating patterns, aiding with recovery from conditions like bulimia and other binge disorders.\n\nIt can also help stimulate appetite and regain a desire to eat in individuals with eating disorders like anorexia. Cannabis can also help reduce anxiety—both social and food related, which can lead many people down the path of eating disorders.\n\n### Benefit #8: Cannabis Provides Relief to PTSD Sufferers\n\nVeterans have become one of the most vocal supporters of cannabis legalization due to the incredible relief that cannabis can provide to people with post-traumatic stress disorder (PTSD). Consuming cannabis can help reduce the stress and anxiety that PTSD sufferers struggle with every day. It also reduces the need for harder opioids and medications that can often worsen the symptoms of PTSD.\n\n### Benefit #9: Cannabis Reduces Nausea\n\nMany people experience nausea on a regular basis, whether it’s due to digestive problems, migraines or chemotherapy. Marijuana reacts with brain receptors to help regulate the feelings that are often associated with nausea.\n\nIt can also help decrease stomach pain and regulate your body’s digestive processes—as digestive issues often go hand in hand with feelings of nausea. Cannabis can also help stimulate appetite if people find themselves unable to hold food down, because they’re experiencing queasiness and an unsettled stomach. \n\n### Benefit #10: CBD Can Reduce Seizure Activity\n\nCBD, the non-psychoactive cannabinoid found in marijuana, can greatly reduce the frequency and severity of seizures. Medical marijuana legalization has been pushed through in many states due to the incredible effects that cannabis has on seizures.\n\nA study from the American Academy of Neurology published in 2015 found that there was, on average, a 51% decrease in the amount of seizures people experienced while using medical cannabis, as well as a 63% decrease in seizures for patients who had Dravet’s syndrome.\n\nA specific marijuana strain, Charlotte’s Web, was created particularly for a young girl who experienced extreme seizures. The strain is still widely used due to its effectiveness and lack of psychoactive side effects. \n\n![Another benefit of marijuana: It makes us feel good](https://hellomd-production.s3.amazonaws.com/articles/588fcc137bf61c000cbbd136/embedded_images/588fcc157bf61c000cbbd137/Screen_Shot_2017-01-30_at_3.13.41_PM.png) \n_Another benefit of marijuana, specifically THC, is that it produces feelings of happiness._ \n\n### Benefit #11: Cannabis Makes You Happy\n\nLastly, for the vast majority of people, [marijuana induces a sense of euphoria and calm](https://www.hellomd.com/health-wellness/582b86cce686fc000c657034/why-does-cannabis-make-you-feel-good). Happiness, or a general sense of well-being is something that everyone wants. Scientific studies show a connection between happiness, optimism and overall life satisfaction.\n\nCannabis activates a neurotransmitter in our brain called anandamide—also called the bliss molecule. This molecule, among other things, is responsible for making us feel happy. THC is responsible for stimulating anandamide, which is found both within our body as well as within cannabis itself.\n\nIf you’re new to cannabis and want to learn more, take a look at our [Cannabis 101](https://hellomd.com/articles/cannabis-101-your-quick-guide-to-medical-marijuana) post. [HelloMD](https://www.hellomd.com/) can help you get your medical marijuana recommendation; it's easy, private and 100% online.","image":{"childImageSharp":{"fluid":{"base64":"data:image/jpeg;base64,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","aspectRatio":1.3333333333333333,"src":"/static/b0878d76d079f1945e473d7543502f16/14b42/12490c05851613cd37353723f5bce115.jpg","srcSet":"/static/b0878d76d079f1945e473d7543502f16/f836f/12490c05851613cd37353723f5bce115.jpg 200w,\n/static/b0878d76d079f1945e473d7543502f16/2244e/12490c05851613cd37353723f5bce115.jpg 400w,\n/static/b0878d76d079f1945e473d7543502f16/14b42/12490c05851613cd37353723f5bce115.jpg 800w,\n/static/b0878d76d079f1945e473d7543502f16/47498/12490c05851613cd37353723f5bce115.jpg 1200w,\n/static/b0878d76d079f1945e473d7543502f16/54ac5/12490c05851613cd37353723f5bce115.jpg 1365w","srcWebp":"/static/b0878d76d079f1945e473d7543502f16/58556/12490c05851613cd37353723f5bce115.webp","srcSetWebp":"/static/b0878d76d079f1945e473d7543502f16/61e93/12490c05851613cd37353723f5bce115.webp 200w,\n/static/b0878d76d079f1945e473d7543502f16/1f5c5/12490c05851613cd37353723f5bce115.webp 400w,\n/static/b0878d76d079f1945e473d7543502f16/58556/12490c05851613cd37353723f5bce115.webp 800w,\n/static/b0878d76d079f1945e473d7543502f16/99238/12490c05851613cd37353723f5bce115.webp 1200w,\n/static/b0878d76d079f1945e473d7543502f16/5e0b8/12490c05851613cd37353723f5bce115.webp 1365w","sizes":"(max-width: 800px) 100vw, 800px"}}}}},{"node":{"id":"Article_1909-markdown","title":"Hemp and Cannabis for Medicinal Purposes: Is There a Difference?","slug":"hemp-and-cannabis-for-medicinal-purposes-is-there-a-difference","content":"With [23 states and the District of\r\nColumbia](http://www.governing.com/gov-data/state-marijuana-laws-map-medical-recreational.html)\r\nhaving legalized medical marijuana to some degree, health-related\r\ncannabis products are growing. Some of these products are hemp-based and\r\nsome are marijuana-based, but what is the difference?\r\n\r\nHemp Versus Marijuana\r\n---------------------\r\n\r\nHemp and marijuana are two varieties of the same plant, cannabis sativa.\r\nHemp refers to a variety that has agricultural and manufacturing uses,\r\nwhile marijuana is the name traditionally given to plants grown for\r\ntheir psychotropic effects. Differences include:\r\n\r\n-   **How they are cultivated.** Hemp is grown outdoors whereas\r\n    marijuana is grown both outdoors and indoors.\r\n-   **Their size and structure.** Hemp grows between 10 and 16 feet in\r\n    height and looks like bamboo. Marijuana is less than 5 feet tall, is\r\n    bushy and has more flowers.\r\n-   **Their utility.** Hemp is used to make textiles, rope, paper,\r\n    plastic, food, body care products, nutritional supplements,\r\n    essential oils and medicine. Marijuana is primarily used for\r\n    recreational and medicinal purposes.\r\n-   **The cannabinoid composition.** According to the [U.S. Department\r\n    of\r\n    Agriculture](http://www.ers.usda.gov/media/328202/ages001eb_1_.pdf),\r\n    hemp contains less than 1 percent tetrahydrocannabinol (THC), which\r\n    is the chemical associated with marijuana's high. In contrast,\r\n    marijuana contains between 3 percent and 15 percent THC.\r\n\r\nLegal Usage\r\n-----------\r\n\r\nAnother distinction between hemp-based and marijuana-based products is\r\ntheir\r\n[legality](https://www.leafly.com/news/health/are-hemp-derived-cbd-products-a-legal-alternative-for-patients-wi).\r\nProducts derived from marijuana can only be sold in states that have\r\npassed medical marijuana legislation. Hemp-derived products, on the\r\nother hand, are legal in all 50 states.\r\n\r\nUntil recently, hemp was illegal to grow in the United States, so all\r\nhemp-based products were imported. In the past few years, some states\r\nbegan allowing for academic and agricultural hemp research, as well as\r\nexploration for potential commercial opportunities. In 2014, [federal\r\nlegislation](http://www.votehemp.com/PR/2014-02-07-vh_farm_bill_signed.html)\r\nwas signed approving hemp research in states that had previously passed\r\nhemp laws.\r\n\r\nHemp Oil\r\n--------\r\n\r\nOne medical product on the market is hemp oil. Hemp oil is made from\r\nseeds or from processed hemp stalks. While touted to be full of\r\n[CBD](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579248/), which is\r\nused to treat nausea, vomiting, seizures, inflammation, mood disorders\r\nand pain, hemp oil is not regulated. Thus, the amount of CBD may not be\r\noptimal for medical purposes.\r\n\r\nIn addition, hemp oil is high in polyunsaturated fats. Excess\r\npolyunsaturated fats have been linked to cardiac problems, increased\r\nrisk of inflammation and tumor growth. Some who have taken hemp oil\r\nreport [side\r\neffects](https://healthyhempoil.com/hemp-oil-side-effects/#.Vdz9d_lViko)\r\nincluding diarrhea, cramping, anxiety, hallucinations and problems with\r\nexcess bleeding.\r\n\r\nFinally, hemp oil may contain soil contaminants, such as heavy metals,\r\nthat may not be filtered out of the final product. So when seeking\r\nmedical cannabis solutions, be sure to purchase your cannabis product\r\nfrom a reputable dispensary that has had its product tested for purity\r\nand safety.\r\n\r\nComparison\r\n----------\r\nBoth Hemp and Cannabis have noticeable levels of CBD, which is beneficial in many medical applications. \r\nMany experts, however, believe that CBD derived from Cannabis can be more effective. \r\nIt is seen as more effective because of the 'entourage effect', how the cannabinoids all work together in the body.\r\n\r\n[Photo Credit.](https://www.flickr.com/photos/fallout/2542501063/in/photolist-4SEYZe-7fx5Nr-5WrQ1o-7fwTAe-6Pq5ZL-33PPZx-bEJnhY-5WrYEE-6jx3oS-7ZL9gX-avDpEi-5WnvPn-5WrZX5-afrEhm-7fMnkT-k3Bv6-6w36Z8-afp3Tg-9EPupv-9F8Cpy-e1ubLE-afogj8-afoHe4-afrcD3-afrGuY-e1oGRH-xaSkpq-hSVaYN-oG1Ky7-oG2dB2-oG1ur2-egrd2T-t7QCd-oG1JPw-oG2a1p-oYeNxx-79NqqA-EsG2w-oG1ZMW-oWtkKd-oWtkFf-c6yUVs-9F5Gsa-9F8AK1-dALh9Z-8jpH4h-oYtvqj-oWtnHw-eZbsSj-kPWX7)","image":{"childImageSharp":{"fluid":{"base64":"data:image/jpeg;base64,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","aspectRatio":1.5037593984962405,"src":"/static/3ea72a49e3fb65d9ed788a56380196fa/14b42/8df0da7aa8d11fec29dbad6a19e0a132.jpg","srcSet":"/static/3ea72a49e3fb65d9ed788a56380196fa/f836f/8df0da7aa8d11fec29dbad6a19e0a132.jpg 200w,\n/static/3ea72a49e3fb65d9ed788a56380196fa/2244e/8df0da7aa8d11fec29dbad6a19e0a132.jpg 400w,\n/static/3ea72a49e3fb65d9ed788a56380196fa/14b42/8df0da7aa8d11fec29dbad6a19e0a132.jpg 800w,\n/static/3ea72a49e3fb65d9ed788a56380196fa/47498/8df0da7aa8d11fec29dbad6a19e0a132.jpg 1200w,\n/static/3ea72a49e3fb65d9ed788a56380196fa/a6974/8df0da7aa8d11fec29dbad6a19e0a132.jpg 1536w","srcWebp":"/static/3ea72a49e3fb65d9ed788a56380196fa/58556/8df0da7aa8d11fec29dbad6a19e0a132.webp","srcSetWebp":"/static/3ea72a49e3fb65d9ed788a56380196fa/61e93/8df0da7aa8d11fec29dbad6a19e0a132.webp 200w,\n/static/3ea72a49e3fb65d9ed788a56380196fa/1f5c5/8df0da7aa8d11fec29dbad6a19e0a132.webp 400w,\n/static/3ea72a49e3fb65d9ed788a56380196fa/58556/8df0da7aa8d11fec29dbad6a19e0a132.webp 800w,\n/static/3ea72a49e3fb65d9ed788a56380196fa/99238/8df0da7aa8d11fec29dbad6a19e0a132.webp 1200w,\n/static/3ea72a49e3fb65d9ed788a56380196fa/d5052/8df0da7aa8d11fec29dbad6a19e0a132.webp 1536w","sizes":"(max-width: 800px) 100vw, 800px"}}}}}]}},"pageContext":{"limit":12,"skip":0,"numPages":1,"currentPage":1,"id":5727,"name":"Seizures","slug":"seizures","country":"US"}},"staticQueryHashes":["3949754563","4179947113","4202924991"]}